Results 71 to 80 of about 659,954 (193)

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]

, 2007
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Alfredsson, L, Burkhardt, H, Holmdahl, Rikard,, Kallberg, H, Klareskog, L, Lindqvist, Anna-Karin,, Lund University., Olsson, Lina,, Padyukov, L   +8 more
core   +2 more sources

Genes as Cues of Relatedness and Social Evolution in Heterogeneous Environments. [PDF]

PLoS Computational Biology, 2016
There are many situations where relatives interact while at the same time there is genetic polymorphism in traits influencing survival and reproduction. Examples include cheater-cooperator polymorphism and polymorphic microbial pathogens.
Olof Leimar, Sasha R X Dall, Peter Hammerstein, John M McNamara   +3 more
doaj   +1 more source

Genetic variants and the metabolic syndrome: a systematic review [PDF]

, 2011
Several candidate gene studies on the metabolic syndrome (MetS) have been conducted. However, for most single nucleotide polymorphisms (SNPs) no systematic review on their association with MetS exists.
Boer, J.M., Feskens, E.J.M., Povel, C.M.
core   +3 more sources

Polimorfismos do gene da interleucina-13 nas posições -1055 C/T e +2044 G/A em pacientes com carcinoma espinocelular de cabeça e pescoço Interleukin-13 gene polymorphisms at -1055 C/T and +2044 G/A positions in patients with squamous cell carcinoma of head and neck

Brazilian Journal of Otorhinolaryngology, 2012
O carcinoma espinocelular (CEC) é a neoplasia mais comum do trato aerodigestivo superior. A interleucina-13 (IL-13) é uma citocina imunorreguladora com polimorfismos relatados para seu gene associados com a mesma doença, especialmente asma e alergia.
Bijan Khademi, Seyed Basir Hashemi, Abbass Ghaderi, Ali Shahrestani, Mohammad Mohammadianpanah   +4 more
doaj   +1 more source

A multi-factorial genetic model for prognostic assessment of high risk melanoma patients receiving adjuvant interferon [PDF]

, 2012
Purpose: IFNa was the first cytokine to demonstrate anti-tumor activity in advanced melanoma. Despite the ability of high-dose IFNa reducing relapse and mortality by up to 33%, large majority of patients experience side effects and toxicity which ...
Alessandro Monaco, Ena Wang, Francesco M. Marincola, Helen Gogas, John M. Kirkwood, Lorenzo Uccellini, Maria Spyropoulou-Vlachou, Monica C. Panelli, Sophia N. Karagiannis, Yingdong Zhao   +9 more
core   +4 more sources

O polimorfismo AGT*M235T na disfunção cardíaca de etiologia isquêmica aguda: projeto gisca AGT*M235T polymorphism in acute ischemic cardiac dysfunction: the gisca project

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: O polimorfismo AGT*M235T tem sido associado a elevados níveis séricos de angiotensinogênio (AGT), hipertensão arterial sistêmica e disfunção cardíaca (DC). OBJETIVO: Testar a hipótese de haver associação entre polimorfismo AGT*M235T e o risco
Claudia Guerra Murad Saud, Amália Faria dos Reis, Arlisa Monteiro de Castro Dias, Rosemery Nunes Cardoso, Ana Cristina Klem Vargas Carneiro, Leandro Pereira de Souza, Ana Beatriz Monteiro Fonseca, Georgina Severo Ribeiro, Carlos Augusto Cardozo de Faria   +8 more
doaj  

A population-based study of glutathione-S-transferase M1, T1 and P1 genotypes [PDF]

, 2008
A retrospective study on healthy, unrelated subjects was conducted in order to estimate population glutathione-S-transferases (GST) genotype frequencies in Slovak population of men and compare our results with already published data (GSEC project)^1^.
Duš, Iveta Waczulí, Já, Jozef Hatok, Monika Sivoň, Peter Rač, Tatiana Matá   +6 more
core   +1 more source

The potential role of genetic markers in talent identification and athlete assessment in elite sport [PDF]

, 2018
In elite sporting codes, the identification and promotion of future athletes into specialized talent pathways is heavily reliant upon objective physical, technical, and tactical characteristics, in addition to subjective coach assessments.
Anderton, Ryan S, Hart, Nicolas H, Jacob, Ysabel, Spiteri, Tania   +3 more
core   +2 more sources

Polimorfismos beta1-adrenérgico associados com Fibrilação Atrial na Insuficiência Cardíaca Sistólica Beta1-adrenergic receptor polymorphisms associated with atrial fibrillation in systolic heart failure

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: O sistema nervoso simpático apresenta grande importância na patogênese da fibrilação atrial na insuficiência cardíaca sistólica. A identificação de polimorfismos no gene ADBR1 do receptor beta1-adrenérgico representa um importante passo no ...
Bruno Costa do Nascimento, Sabrina Bernardez Pereira, Georgina Severo Ribeiro, Evandro Tinoco Mesquita   +3 more
doaj  

Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy. [PDF]

, 2019
Cancer-related cognitive impairment (CRCI) adversely affects cancer patients. We had previously demonstrated that the BDNF Val66Met genetic polymorphism is associated with lower odds of subjective CRCI in the multitasking and verbal ability domains among
Beh, Sok Yuen, Chan, Alexandre, Chan, Jack Junjie, Chay, Wen Yee, Chu, Pat, Dent, Rebecca A, Foo, Koon Mian, Ho, Han Kiat, Jain, Amit, Khor, Chiea Chuen, Koo, Si-Lin, Lee, Guek Eng, Lim, Elaine H, Lim, Sheree Wan Ting, Loh, Kiley Wei-Jen, Ng, Raymond Chee Hui, Ng, Terence, Shwe, Maung, Tan, Chia Jie, Tan, Tira Jing Ying, Toh, Yi Long, Wong, Mabel, Yap, Yoon Sim, Yeo, Angie   +23 more
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