Results 91 to 100 of about 144,897 (315)

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

Development of a molecular method for the rapid screening and identification of the three functionally relevant polymorphisms in the human TAS2R38 receptor gene in studies of sensitivity to the bitter taste of PROP [PDF]

open access: yes, 2015
The objective of this work was to develop a rapid screening method to identify the three single nucleotide polymorphisms (SNPs) in the TAS2R38 gene, with the aim of providing a significant contribution to studies designed to assess sensitivity to the ...
Atzori, E, Orrù, R, Padiglia, A
core   +2 more sources

The Emerging Parkinson's Disease Oxylipin‐Ome

open access: yesAdvanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Análisis de polimorfismos en los genes tripanotión reductasa y cruzipaína en cepas colombianas de Trypanosoma cruzi

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2007
Introducción. Los estudios genéticos en Trypanosoma cruzi han buscado establecer asociaciones de variantes genéticas del parásito con manifestaciones clínicas de la enfermedad, origen biológico y geográfico de los aislamientos; sin embargo, los ...
Winston Rojas   +5 more
doaj   +1 more source

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

A comparison between CHROMagar, PCR-RFLP and PCR-FSP for identification of Candida species

open access: yesCurrent Medical Mycology, 2017
Background and Purpose: The epidemiological alteration in the distribution of Candida species, as well as the significantly increasing trend of either intrinsic or acquired resistance of some of these fungi highlights the need for a reliable method for ...
Zahra Jafari   +5 more
doaj  

Possibilities of using nested PCR-RFLP for taxonomic identification of L3 larvae of the family Trichostrongylidae, Leiper, 1912

open access: yesРоссийский паразитологический журнал
The purpose of the research is to apply molecular genetic research methods to identify the taxonomic affiliation of gastrointestinal parasitic sheep nematodes of the family Trichostrongylidae using nested PCR followed by the restriction fragment length ...
I. A. Pimenov   +3 more
doaj   +1 more source

Aplicação da biologia molecular em programas de conservação de recursos pesqueiros. [PDF]

open access: yes, 2013
Estudos genéticos em peixes; Marcadores moleculares; Eletroforese de proteínas; Seqüências de DNA como marcadores; Polimorfismo de comprimento de fragmentos de restrição (Restriction Fragment Length Polymorphism - RFLP); Polimorfismo de DNA amplificado ...
MARQUES, D. K. S.
core   +1 more source

RESTRICTION FRAGMENT LENGTH POLYMORPHISM IN CARROT

open access: yesHortScience, 1993
Studies of genetic variation at the DNA level in the genus Daucus have been very limited. Recently, molecular markers based on restriction fragment length polymorphism (RFLP) have been shown to be highly useful and efficient gene markers in other plant and animal species.We have used a total of 40 carrot strains (inbreds, varieties, species) for this ...
Vivek Sampath, Philipp Simon
openaire   +1 more source

Deciphering the Evolution Pattern of Structural Variations Overlapped With Repetitive Sequence During Cattle Evolution

open access: yesAdvanced Science, EarlyView.
The authors complement bovine pan‐SV with massive novel structural variations (SVs) identified through long‐read sequencing of 83 globally distributed cattle breeds. Repetitive sequence‐mediated SVs (rep‐SV) exhibit distinct dynamic patterns throughout cattle sub‐speciation and/or domestication processes, including uneven distribution between chr‐X and
Zhifan Guo   +16 more
wiley   +1 more source

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