Results 111 to 120 of about 4,583 (217)

Clinical predictors of response to methotrexate in patients with rheumatoid arthritis: A systematic review

open access: yesRheumatology &Autoimmunity, EarlyView.
This review integrates clinical, immunological, genetic, and multi‐omic evidence, highlighting dynamic inflammatory and adenosine‐pathway biomarkers and reinforcing treat‐to‐target principles as the most actionable framework for personalized methotrexate therapy.
Joana Ramos Rodrigues   +6 more
wiley   +1 more source

Colloidal Behavior of Carbonate Particles Microbially Precipitated in Microfluidic Droplets

open access: yesSmall, EarlyView.
In Microbially Induced Calcium Carbonate Precipitation (MICP), ureolytic bacteria trigger calcium carbonate precipitation via pH‐increasing urea hydrolysis. This enzymatically driven reaction induces the colloidal assembly of bacteria and carbonate particles into fractal networks.
Nadia Enrriquez Casimiro   +5 more
wiley   +1 more source

One‐Pot Fabrication of Pentapeptide Bio‐Aerogel via Direct Alcogelation

open access: yesSmall, EarlyView.
A minimal tachykinin‐inspired pentapeptide (TC‐1) self‐assembles in water and ethanol to form robust gels that can be dried in one pot to ultra‐porous aerogels using supercritical carbon dioxide. Solvent choice programs nanoscale packing and bulk mechanics producing lightweight monoliths with high porosity for biomaterials applications, verified by ...
Brody McDonald   +6 more
wiley   +1 more source

Engineering metal‐organic framework‐based smart porous nanoplatforms for targeted therapy and theranostic applications

open access: yesSmart Molecules, EarlyView.
MOFs offer high porosity and tunability for biomedical applications, especially in cancer therapy via ROS generation and targeted delivery. Though toxicity, stability, and scalability remain key clinical challenges. Drug loading in MOFs exceeds 60%–70% with controlled release behavior.
Jagabandhu Bag   +6 more
wiley   +1 more source

Effect of Glutathione S‐Transferase and Metallothionein Polymorphisms on Mercury Levels and End‐Stage Renal Disease (ESRD) in Colombian Patients

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Epidemiological studies have demonstrated a link between chronic kidney disease (CKD) and environmental mercury (Hg) exposure. Colombia has a well‐documented history of artisanal and small‐scale gold mining, where Hg exposure affects miners and nearby riverside and urban populations. This study aimed to evaluate the effects of polymorphisms in
Diana M. Narváez   +16 more
wiley   +1 more source

Taxogenomic Characterization and Comparative Genomic Analysis of Hermanozyma buritii sp. nov., f.a., a Yeast Species Isolated From Plants and Soil

open access: yesYeast, EarlyView.
Isolation of the novel yeast species Hernanozyma buritii sp. nov. from soil and plant in Brazil, followed by phylogenetic characterization and genome analysis, highlighting its relationship with closely related taxa and genomic features associated with mating, pulcherriminic acid biosynthesis, and iron‐dependent pigmentation.
Vitória Petra de O. Barros   +11 more
wiley   +1 more source

Testicular Echobiometry and Sperm Characterization in Oncilla (Leopardus tigrinus) From the Caatinga Biome

open access: yesZoo Biology, EarlyView.
We describe testicular echobiometry and sperm characterization in oncilla (Leopardus tigrinus) from the Caatinga biome, Ceará, Brazil. ABSTRACT Among neotropical small felids, the Leopardus tigrinus is classified as vulnerable by the International Union for Conservation of Nature, but studies on reproductive morphology and physiology are scarce for ...
Yuri Gonçalves Matos   +8 more
wiley   +1 more source

Cryptic variation within and among islands in the ultraviolet reflectance of lizard throat coloration

open access: yesJournal of Animal Ecology, EarlyView.
Identifying the existence of ‘cryptic’ morphs is critical in animal ecology for providing a basis for accurately testing links between phenotype and environment. This study identifies the existence of previously undocumented variation in UV reflectance in Aegean wall lizards that likely has novel behavioural and evolutionary implications within this ...
Hayley L. Crowell   +2 more
wiley   +1 more source

Museomics Deciphers the Phylogeographic Differentiation and Conservation Status of a Montane Pheasant

open access: yesIntegrative Zoology, EarlyView.
Museum specimens provide a rich source of historical DNA, enabling insights into phylogenetic relationships and demographic history of the endangered Koklass Pheasant. Our findings uncovered a previously unrecognized population in Guizhou province and highlighted elevated extinction risk in populations from Anhui province and Southern China, informing ...
Zhiyong Jiang   +9 more
wiley   +1 more source

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