Results 131 to 140 of about 4,583 (217)
Integrative Zoology, EarlyView.Here, we adopt an integrative framework (molecular phylogenetics and geometric morphometrics) to reassess patterns of diversity and differentiation across this region. We analyzed cytochrome b sequences and quantified cranial shape variation. Our analyses indicate the presence of three species groups (mendocinus, talarum, and tucumanus) and two ...
Facundo Contreras +4 more
wiley +1 more source
Captive Breeding of the Chinese Alligator Reduces Inbreeding but Increases Genetic Load
Integrative Zoology, EarlyView.Captive breeding of the Chinese alligator successfully reduced genomic inbreeding but increased the burden of deleterious mutations. Genomic analyses indicate that managing both genetic diversity and genetic load is essential for the long‐term conservation of this critically endangered species.
Yihang Fan +3 more
wiley +1 more source
Genomic Diversity of the Endangered Guinan Toad‐Headed Lizard and Its Conservation Implications
Integrative Zoology, EarlyView.We produced HiFi long reads and assembled a high‐quality genome for the Guinan toad‐headed lizard—Phrynocephalus guinanensis—and present a comprehensive conservation genomics assessment. Our findings clearly show population structure, a reduced genetic diversity pattern, and a strong bottleneck in demographic history, reaffirming the endangered status ...
Ying Chen +5 more
wiley +1 more source
Methods in Ecology and Evolution, EarlyView.Abstract Environmental DNA (eDNA) analyses have become a powerful tool for non‐invasive biodiversity monitoring, yet the applicability of population‐genetic approaches to environmental samples remains largely unexplored. Even when genetic traces originate from a single individual, low target DNA concentrations and amplification or sequencing artefacts ...
Lauren Kelly Rodriguez +8 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche +11 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani +8 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Genetic variability within the follicle‐stimulating hormone (FSH)‐related genes might contribute to phenotypic heterogeneity in patients with Klinefelter syndrome (KS), yet its clinical impact on sperm retrieval remains unclear. Objectives To investigate the association between FSHB c.211 G > T and FSHR polymorphisms (c.2039 A > G ...
Andrea Graziani +6 more
wiley +1 more source
CD93—An emerging vascular target in cancer therapy
British Journal of Pharmacology, EarlyView.Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira +3 more
wiley +1 more source
Cladistics, EarlyView.Abstract Cingulata, a major lineage of Xenarthra, comprises extinct and extant armoured placental mammals that diversified throughout the Cenozoic. Despite extensive study, phylogenetic hypotheses based on morphological and molecular data remain incongruent, and no total evidence analysis has been conducted. Here, we integrate the largest morphological
Daniel M. Casali +7 more
wiley +1 more source
Cladistics, EarlyView.Abstract Subterranean ecosystems harbour exceptional biodiversity shaped by adaptation to extreme environments, yet remain poorly explored. Cave organisms, restricted to small, isolated populations, are extinction‐prone, making integrative species delimitation essential for biodiversity assessment and conservation.
Dora Hlebec +3 more
wiley +1 more source