rDNAmine: A New Tool for the Analysis of Long Repetitive Sequences
This work introduces a novel approach for analysing long repetitive genomic sequences, combining a method to isolate large DNA molecules from individual chromosomes. We also describe the bioinformatics tool rDNAmine, which enables the isolation of long‐repeat sequences from reads obtained using the Oxford Nanopore method, as well as their preliminary ...
Agnieszka Czarnocka‐Cieciura +1 more
wiley +1 more source
Discrimination of Hard Ticks by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). [PDF]
Perumalsamy N +4 more
europepmc +1 more source
Unusual backfolded binding poses of BAZ2A bromodomain binders
We identified BAZ2A‐binding compounds assuming a peculiar, almost enclosed, conformation. These molecules pose a basis for the development of potent BAZ2A macrocyclic inhibitors, as performed for other bromodomains.BAZ2A is a large multidomain protein overexpressed in aggressive prostate cancer, where it potentiates migration and invasion of other ...
Andrea Dalle Vedove +5 more
wiley +1 more source
Long non-coding RNA maternally expressed gene 3 (<i>MEG3</i>) rs4081134 gene polymorphism and preeclampsia risk. [PDF]
Saljoughi S +6 more
europepmc +1 more source
Recovery of male DNA acquired from carrion‐feeding insects in a simulated sexual assault scenario
Abstract When bodies of sexual assault victims are discovered in advanced stages of decomposition, the recovery of direct DNA evidence is often compromised, posing a challenge in criminal investigations. This study aimed to determine insect colonization and succession patterns on pig carcasses inoculated with semen and to assess the feasibility of ...
Tinotenda Angel Mupfumi +2 more
wiley +1 more source
The T Allele of the HNMT C314T Polymorphism Is Associated with a Reduced Risk of Idiopathic Parkinson's Disease in Mexican Patients. [PDF]
Bueno-Nava A +10 more
europepmc +1 more source
Genetic differentiation and adaptive evolution of buff‐tailed bumblebees in Asia
This study investigates the genetic differentiation and local adaptation of the buff‐tailed bumblebee (Bombus terrestris) across its European and Asian populations. Using whole‐genome resequencing, we identified distinct genetic differences between populations, with Asian B. terrestris representing a unique genetic resource.
Long Su +14 more
wiley +1 more source
The Specific Low-Interference dsDNA Copper Nanoclusters for Visual Fluorescent Detection and Quantification of the <i>EGFR</i> L858R Point Mutation in Whole Single-Tube Magnetic Purification System. [PDF]
Lai KP +4 more
europepmc +1 more source
Museum specimens provide a rich source of historical DNA, enabling insights into phylogenetic relationships and demographic history of the endangered Koklass Pheasant. Our findings uncovered a previously unrecognized population in Guizhou province and highlighted elevated extinction risk in populations from Anhui province and Southern China, informing ...
Zhiyong Jiang +9 more
wiley +1 more source

