Results 211 to 220 of about 149,237 (266)

Winter‐active spiders (Clubiona) have a hyperactive antifreeze protein with a unique beta‐solenoid fold

open access: yesThe FEBS Journal, EarlyView.
Antifreeze proteins from winter‐active spiders were purified using their affinity for ice. After LC–MSMS characterization, corresponding transcripts were identified. The antifreeze protein folds as a β‐solenoid with a large flat ice‐binding site on one surface and can bind to ice crystals and prevent their growth at −4 °C.
Laurie A. Graham   +3 more
wiley   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

open access: yesThe FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio   +12 more
wiley   +1 more source

The association of the SIRT6 rs117385980 variant with frailty and longevity: an exploratory study. [PDF]

open access: yesSci Rep
Sheikholmolouki E   +6 more
europepmc   +1 more source

Toward a global repository of insect traits (GRIT)

open access: yesInsect Conservation and Diversity, EarlyView.
Biodiversity loss is accelerating, yet insect conservation is hindered by the absence of a centralised, comprehensive trait database. We propose the GRIT, a FAIR, open‐access platform uniting datasets and collaborators worldwide. GRIT will harness advanced computational tools for trait acquisition and imputation, enabling large‐scale ecological ...
Pedro Cardoso   +37 more
wiley   +1 more source

Molecular Testing in Sickle Cell Disease: From Newborn Screening to Transfusion Care

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Sickle cell disease (SCD) is one of the most frequent monogenic diseases worldwide and a highly heterogeneous and complex disease. SCD care carries several challenges. This includes early and accurate diagnosis as well as optimal red blood cell transfusion matching in this population carrying a high risk of alloimmunization.
Thomas Pincez, Yves D. Pastore
wiley   +1 more source

Genetic and Epigenetic Mechanisms Underpinning Biotic Stress Resilience of <i>Brassica</i> Vegetables. [PDF]

open access: yesPlants (Basel)
Akter MA   +6 more
europepmc   +1 more source

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

open access: yesInsect Molecular Biology, EarlyView.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro   +4 more
wiley   +1 more source

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