Results 61 to 70 of about 6,098 (217)
Protein design and RNA design: Perspectives
Quantitative Biology, Volume 14, Issue 2, June 2026.Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley +1 more source
Protein Science, Volume 35, Issue 4, April 2026.Abstract Oligomeric assemblies of amyloidogenic proteins, such as Aβ, tau, α‐synuclein, amylin, transthyretin, and TDP‐43, are increasingly recognized as key drivers of cellular dysfunction across a range of neurodegenerative and systemic disorders.
Magdalena I. Ivanova +2 more
wiley +1 more source
Revista Colombiana de Biotecnología, 2009 Las cefotaximasas (CTX-M) son las beta-lactamasas de espectro extendido más ampliamente diseminadas entre especies de la familia Enterobacteriaceae, y son la causa principal de resistencia en aislamientos causantes de infección intrahospitalaria.
José Ramón Mantilla Anaya +3 more
doaj +2 more sources
Variation in the Fatty Acid Synthase Gene (FASN) and Its Association with Milk Traits in Gannan Yaks
Animals, 2019 Fatty acid synthase (FASN) is an enzyme involved in the synthesis of fatty acids (FA) and plays a central role in de novo lipogenesis in mammals. This study was conducted to ascertain the relative level of expression of the FASN gene (FASN) in tissues ...
Bingang Shi +7 more
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Protein Science, Volume 35, Issue 4, April 2026.Abstract Alpha‐synuclein (αSyn) is a presynaptic protein associated with several neurodegenerative diseases. While the non‐amyloid component (NAC) region of the αSyn sequence (residues 65–90) forms the core of all αSyn fibrils, recent findings suggest that the flanking regions play a key role in initiating or preventing amyloid formation. Two motifs in
Van T. T. Nguyen +4 more
wiley +1 more source
Determination of apolipoprotein E genotypes by single-strand conformational polymorphism
Clinical Chemistry, 1993 Abstract We used single-strand conformational polymorphism (SSCP) to determine apolipoprotein E (Apo E) genotypes in 47 individuals. A 295-base-pair (bp) DNA fragment coding for amino acid residues 80-178 of the Apo E protein gave distinct patterns for the three alleles.
M Y, Tsai +6 more
openaire +2 more sources
Integration of epigenetics into ecotoxicology: insights and fundamental research needs
Biological Reviews, Volume 101, Issue 2, Page 826-847, April 2026.ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto +3 more
wiley +1 more source
Genetic Identification of Trichomonas vaginalis by Using the Actin Gene and Molecular Based Methods
Iranian Journal of Parasitology, 2014 Background: Trichomonas vaginalis is the agent of urogenital tract infection that causes human trichomoniasis with some serious health complications.
Mohammad Matini +6 more
doaj
FSHR (exon 10) gene polymorphisms and its association with fertility trait in Egyptian Ossimi sheep [PDF]
Biotechnology in Animal Husbandry, 2019 For the association between of Follicle stimulating hormone receptor (FSHR) gene (partial part of exon 10) polymorphisms and litter size trait in Egyptian Ossimi sheep, polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) and ...
Abdel-Rahman Salah +4 more
doaj
Nasopalpebral lipoma coloboma syndrome
Indian Journal of Ophthalmology, 2011 Nasopalpebral lipoma-coloboma syndrome is characterized by nasopalpebral lipoma and eyelid coloboma. We report a case of a 16-year-old Indian girl who reported to us with this rare syndrome.
N Suresh Babu, D Raviprakash, Ravi Kumar
doaj +1 more source