Results 1 to 10 of about 690,386 (352)

Construction and analysis of single nucleotide polymorphism-single nucleotide polymorphism interaction networks. [PDF]

IET Syst Biol, 2013
The study of gene regulatory network and protein-protein interaction network is believed to be fundamental to the understanding of molecular processes and functions in systems biology.
Liu Y, Li X, Liu Z, Chen L, Ng MK.
europepmc   +6 more sources

TMPRSS2 gene, single nucleotide polymorphism rs8134378, single nucleotide polymorphism rs12329760.

Syrian Journal for Science and Innovation, 2023
Since the spread of the COVID-19 pandemic, there has been a variation in the prevalence rates of the coronavirus that causes the disease, the distribution of moderate and severe symptoms, and death rates, among different populations.
Majd Aljamali , Lama Youssef
doaj   +1 more source

A noncoding single-nucleotide polymorphism at 8q24 drives IDH1-mutant glioma formation

Science, 2022
Establishing causal links between inherited polymorphisms and cancer risk is challenging. Here, we focus on the single-nucleotide polymorphism rs55705857, which confers a sixfold greater risk of isocitrate dehydrogenase (IDH)–mutant low-grade glioma (LGG)
C. Yanchus, K. Drucker, T. Kollmeyer, R. Tsai, M. Liang, L. Jiang, J. Pawling, A. Ali, P. Decker, M. Kosel, A. Panda, A. Malik, K. Al-Zahrani, J. Hernandez, M. Ahmed, S. Loganathan, D. Trcka, A. Michaelraj, J. Fortin, P. Mazrooei, L. Zhou, A. Elia, M. Lupien, H. He, L. Wang, A. Abyzov, J. Dennis, M. Wilson, J. Wrana, D. Lachance, M. Wrensch, J. Wienck, L. Pennacchio, D. Dickel, A. Visel, M. Taylor, G. Zadeh, P. Dirks, J. E. Eckel Passow, T. Mak, E. Kvon, R. Jenkins, D. Schramek   +42 more
semanticscholar   +1 more source

Predicting late-stage age-related macular degeneration by integrating marginally weak SNPs in GWA studies

Frontiers in Genetics, 2023
Introduction: Age-related macular degeneration (AMD) is a progressive neurodegenerative disease and the leading cause of blindness in developed countries.
Xueping Zhou, Jipeng Zhang, Ying Ding, Heng Huang, Yanming Li, Wei Chen   +5 more
doaj   +1 more source

Recent Progress in Single-Nucleotide Polymorphism Biosensors

Biosensors, 2023
Single-nucleotide polymorphisms (SNPs), the most common form of genetic variation in the human genome, are the main cause of individual differences. Furthermore, such attractive genetic markers are emerging as important hallmarks in clinical diagnosis ...
Kaimin Wu, Feizhi Kong, Jingjing Zhang, Ying Tang, Yao Chen, Long Chao, Libo Nie, Zhao Huang   +7 more
doaj   +1 more source

Genomic diversity affects the accuracy of bacterial single-nucleotide polymorphism–calling pipelines

GigaScience, 2020
Background Accurately identifying single-nucleotide polymorphisms (SNPs) from bacterial sequencing data is an essential requirement for using genomics to track transmission and predict important phenotypes such as antimicrobial resistance.
Stephen J. Bush, D. Foster, D. Eyre, Emily L. Clark, Nicola De Maio, Liam P. Shaw, N. Stoesser, T. Peto, D. W. Crook, A. Walker   +9 more
semanticscholar   +1 more source

Association between SORL1 polymorphisms and the risk of Alzheimer's disease [PDF]

Journal of Integrative Neuroscience, 2018
A meta-analysis was performed to identify empirical data assessing the effects of a single nucleotide polymorphisms of sortilin-related receptor on Alzheimer's disease based on 14 studies involving 37941 cases and 49727 control studies. Analysis showed, (
Lele Cong, Xiangyi Kong, Jing Wang, Jianshi Du, Zhongxin Xu, Yanan Xu, Qing Zhao
doaj   +1 more source

Analysis of GLT6D1 and CDKN2BAS gene polymorphisms in Brazilian patients with advanced periodontitis

Brazilian Oral Research, 2022
Gene polymorphisms can predispose to periodontal disease, as demonstrated by the well-documented association between aggressive periodontitis and single nucleotide polymorphisms (SNPs) such as rs153745 in the GLT6D1 gene and rs3217992 in the CDKN2BAS ...
Richelle Soares RODRIGUES, Rodrigo RÊGO, Raquel Mantuaneli Scarel CAMINAGA, Jéssica Marina GOVEIA, Virginia Régia Souza SILVEIRA   +4 more
doaj   +1 more source

Impact of the Polymorphism of the PACRG and CD80 Genes on the Development of the Different Stages of Tuberculosis Infection [PDF]

Iranian Journal of Medical Sciences, 2019
Background: Tuberculosis (TB) is one of the most significant health-care problems worldwide. The host’s genetics play an important role in the development of TB in humans.
Elena Yu. Bragina, Nadezhda P. Babushkina, Anna F. Garaeva, Alexey A. Rudko, Dmitry Yu. Tsitrikov, Densema E. Gomboeva, Maxim B. Freidin   +6 more
doaj   +1 more source

Detection of Single Nucleotide Polymorphism Rs2013162 of IRF6 Gene in Patient with Cleft Lip and Palate [PDF]

, 2019
Background: Cleft lip and palate are congenital disorders which induce affected individuals medically, socially and psychologically. The objective of this study was to investigate the association of Single Nucleotide Polymorphism(SNP); rs2013162 of ...
Shehzad, H. (Husnain), Shehzad, O. (Osheen)   +1 more
core   +4 more sources