International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
<i>CXCL12</i> rs1801157 Polymorphism Is Associated with Antiatherogenic Lipoprotein Subfraction Profile Independent of Coronary Artery Disease Risk in a Turkish Population: A Case-Control Study. [PDF]
J Clin MedDeniz İ +4 more
europepmc +1 more source
Understanding pre‐eclampsia and fetal growth restriction at high altitude: A narrative review
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Pre‐eclampsia (PE) and fetal growth restriction (FGR) are among the leading causes of maternal and perinatal morbidity and mortality worldwide. Both conditions are more frequent and severe at high altitudes due to physiological changes in oxygen availability and vascular adaptation.
Víctor S. Rangel +6 more
wiley +1 more source
Development and characterization of near-isogenic lines for quantitative trait locus qDT.3B.1 underlying drought tolerance in wheat. [PDF]
Plant GenomeCaguiat JD +4 more
europepmc +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective Potential associations between reproductive traits and cognitive function have been discovered; however, the results are inconsistent, and the causalities are unclear. This study utilized Mendelian randomization (MR) analysis to assess the causal impact of reproductive traits on cognitive function.
Xia Wang, Yunyun Guo
wiley +1 more source
The importance of gene polymorphism in familial inheritance of endometriosis
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik +4 more
wiley +1 more source
Alzheimer's disease risk single nucleotide polymorphism rs11218343 is linked to functional expression of SORL1 in microglia. [PDF]
Alzheimers DementGorniak-Walas M +4 more
europepmc +1 more source
The Role of Pharmacogenetics in the Effectiveness of Rheumatoid Arthritis Treatment with Leflunomide. [PDF]
Genes (Basel)Plewa P +5 more
europepmc +1 more source
bacNeo: A Computational Toolkit for Identifying Bacteria‐Derived Neoantigens in Human Cancers
iMetaMed, EarlyView.We present bacterial neoantigen (bacNeo), a multi‐omics‐based computational software to classify bacterial components (BACC), type bacteria‐bound HLA alleles (BACH), and prioritize bacterial peptides as neoantigens (BACP). Bacterial neoantigen potential is quantified by score for peptide antigenicity recognition & kinetics (SPARK), enabling ...
Yunzhe Wang +5 more
wiley +1 more source
The impact of different intensities of physical activity on the risk of venous thromboembolism: A Mendelian randomization study. [PDF]
Medicine (Baltimore)Xie Y, Zhou J, Zhu Y, Xie Y.
europepmc +1 more source