Clinical Relevance of BACH1 Expression in Non–Small Cell Lung Cancer
International Journal of Cancer, EarlyView.ABSTRACT BTB and CNC homolog 1 (BACH1) is a redox‐sensitive transcription factor implicated in tumor progression, metabolic reprogramming, and therapy resistance in several cancers. However, its prognostic significance and role in therapy resistance in non–small cell lung cancer (NSCLC) remain unclear.
Jing Liu +7 more
wiley +1 more source
Causal association between plasma vascular endothelial growth factor family proteins and placenta previa: A 2-sample Mendelian randomization study. [PDF]
Medicine (Baltimore)Hong Z, Xu Z, Huang Z, Li W, Liu Q.
europepmc +1 more source
Familial Cancers Associated With Cancers of the Breast, Prostate, Colorectum, and Lung in Sweden
International Journal of Cancer, EarlyView.ABSTRACT Available epidemiological evidence shows that many cancers share familial risks, and this is increasingly confirmed by data on shared pathogenic germline gene variants between cancers. We decided to harness the world's largest resource on familial cancer to assess discordant familial risks for female breast (BC), prostate (PC), colorectal (CRC)
Frantisek Zitricky +5 more
wiley +1 more source
Genetically predicted ZDHHC8 expression and osteoporosis risk: A two-sample Mendelian randomization and metabolite mediation study. [PDF]
Medicine (Baltimore)Yang W, Yang K, Xu S, Yang S.
europepmc +1 more source
International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng +4 more
wiley +1 more source
The bidirectional causal relationships of insomnia with eleven cancers: A Mendelian randomization study. [PDF]
Medicine (Baltimore)Li J, Cheng L, Li F, Xu Y.
europepmc +1 more source
iMetaMed, EarlyView.Shared genetics pathways connect oral diseases and gut disorders. ABSTRACT Oral diseases are highly prevalent and increasingly recognized as contributors to gastrointestinal disorders. Despite clinical observations of oral–gut comorbidity, the underlying genetic architecture and causal mechanisms remain poorly understood.
Rui Zhang +6 more
wiley +1 more source
Chloroplast Genome Characterization and Phylogenetic Implications of <i>Reyesia</i> and <i>Salpiglossis</i> (Salpiglossideae, Solanaceae). [PDF]
Ecol EvolHuang J, Nong S, Zhang Y, Xu W.
europepmc +1 more source
iMetaOmics, EarlyView.Natural populations of Marchantia polymorpha sampled across contrasting climatic regions show clear geographic differentiation between Europe and Japan based on polymorphic short tandem repeat (STR) variation. Genome‐wide association (GWAS) analyses identified pSTR loci whose repeat‐length variation tracks temperature‐related WorldClim variables.
Shuangyang Wu +4 more
wiley +1 more source
Causal relationship between asthma and hernia risk: A Mendelian randomization study. [PDF]
Medicine (Baltimore)Lu Y +7 more
europepmc +1 more source