Results 231 to 240 of about 305,165 (262)

Progress of metabolomics‐centric multi‐omics research in medicine

iMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang, Shiwen Deng, Xiaoxu Wang, Xiao Chang, Na Guo, Peng Chen, Hongjun Yang   +6 more
wiley   +1 more source

An ARMS-integrated high-resolution melting assay for reliable discrimination of the A1/A2 polymorphism in the bovine <i>CSN2</i> gene. [PDF]

Food Chem (Oxf)
Lee Y, Baek H, Lee J, Lim D, Choi I.
europepmc   +1 more source

Integrated high‐throughput phenomics and transcriptomics uncover the transcriptional mechanisms underlying rice responses to elevated CO2 concentration and cadmium stress

iMetaOmics, EarlyView.
Developing crop varieties with reduced cadmium (Cd) accumulation under elevated carbon dioxide (eCO2) requires hub gene identification and elucidation of its transcriptional mechanisms. Here, we acquired high‐throughput phenotyping of the rice cultivar Nipponbare across six key developmental stages under Cd stress and three eCO2 concentrations.
Weijun Guo, Hanlin Liu, Dongwei Li, Shang Xie, Yichao Mao, Liwen Yang, Cong Li, Weixuan Wang, Jian Tian, Xiaofeng Gu, Li Pu   +10 more
wiley   +1 more source

Identification of Novel Risk Loci for Common B-Cell Lymphoma Subtypes Through Cross-Trait Analysis with Idiopathic Inflammatory Myopathies. [PDF]

Cancers (Basel)
Che WI, Jarvis JN, International Lymphoma Epidemiology Consortium InterLymph, Imacs Genetics Group Myogen, Lundberg IE, Smedby KE, Lamb JA, Holmqvist M.   +7 more
europepmc   +1 more source

Genomic epidemiology and lineage‐specific risk stratification of tet(X4)‐mediated tigecycline resistance along the pork production chain: A One Health perspective

iMetaOmics, EarlyView.
Genome surveillance across a swine‐associated One Health continuum in China shows that slaughterhouses act as major enrichment nodes for tet(X4)‐mediated tigecycline resistance, driven by putative clonal transmission and stable plasmid backbones. Integrating global datasets enables lineage‐specific risk stratification, highlighting key control points ...
Qin Wang, Qiwu Yuan, Xuan Chen, Yujing Zhong, Ke Wu, Renqiao Wen, Luya Liu, Xiaoqin Wang, Cui Li, Hongning Wang, Changwei Lei   +10 more
wiley   +1 more source

Regulatory T Cell-Related Gene Polymorphisms are Associated with Risk of Lung Cancer in Patients with COPD. [PDF]

Int J Chron Obstruct Pulmon Dis
Zhang X, Chen F.
europepmc   +1 more source

Association Between Polymorphisms in Genes Encoding PD-1/PD-L1 Molecules and Clinicopathological Features in Clear Cell Renal Cell Carcinoma. [PDF]

Int J Mol Sci
Onyszczuk M, Szweda-Gandor N, Rynkiewicz M, Drozdzowska B.   +3 more
europepmc   +1 more source

Identification of resistance sources and genomic regions regulating spot blotch resistance in Asian bread wheat (Triticum aestivum L.) via genome-wide association study. [PDF]

Plant Genome
Aggarwal N, He X, Rathore M, Jan F, Gupta V, Mir RR, Singh PK.   +6 more
europepmc   +1 more source

Women with Abdominal Aortic Aneurysms Have a Different Pattern of Genetic Variability, Compared to Men. [PDF]

Biomedicines
Wallinder J, Wanhainen A, Åkerud H, Wågsäter D, Björck M.   +4 more
europepmc   +1 more source

Genetic control of wheat flour end-use quality and rheology by genome-wide association studies. [PDF]

Plant Genome
Menor de Gaspar J, Cuthbert RD, Yuefeng R, Knox R, Fu B, Wang K, Sangah JS, Berraies S, Meyer B, Bokore FE, Isidro Y Sánchez J.   +10 more
europepmc   +1 more source