Results 251 to 260 of about 709,557 (336)

Causal effects of breastfeeding on childhood health outcomes: A Mendelian randomization analysis of mental and physical health. [PDF]

Medicine (Baltimore)
Lu Y, Yu X, Feng Z, Xiang Z, Xu F, Zheng J, Rui S, Yue X, Zhao Y.   +8 more
europepmc   +1 more source

A Comprehensive Review of Probiotics in Alleviating Hyperuricemia: Mechanisms, Strain Engineering, and Food Applications

Food Bioengineering, EarlyView.
Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang, Qi Wu, Mengjia Zhang, Zifu Ni, Pengshuai Zhang, Siyuan Bai, Yibin Wang, Zhongke Sun   +7 more
wiley   +1 more source

Advanced glycation end-product receptor gene (RAGE) polymorphisms in patients with acute coronary syndrome - a case-control study in the Polish population. [PDF]

BMC Med Genomics
Gutowska K, Ambroziak M, Podraza J, Puzianowska-Kuźnicka M, Czajkowski K, Budaj A, Kuryłowicz A.   +6 more
europepmc   +1 more source

Initial investigations into single nucleotide polymorphisms and their association with QTc and left ventricular function in peripartum cardiomyopathy

European Journal of Heart Failure, EarlyView.
Gasnat Shaboodien, Charle Viljoen, Polycarp Ndibangwi, Julian Hoevelmann, Lameez Pearce, Susanna Haidari, Margherita Torchio, Federica Dagradi, Carla Spazzolini, Sarah Kraus, Ntobeko A.B. Ntusi, Peter J. Schwartz, Karen Sliwa   +12 more
wiley   +1 more source

Marine n‐3 Polyunsaturated Fatty Acids Mitigate Obesity Traits Through PRDM16‐Driven Gene–Nutrient Interaction and Spatiotemporal Scale Browning Process

Food Frontiers, EarlyView.
This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu, Haoyu Li, Youyou Zheng, Xiaoqian Chen, Xuzhi Wan, Pan Zhuang, Wei Jia, Jianxin Yao, Haoyin Liu, Hongbo Shi, Xunan Lin, Yu Zhang, Jingjing Jiao   +12 more
wiley   +1 more source

Deciphering the immunometabolic axis: a mendelian randomization study of a causal cascade network from immune cell phenotypes to metabolites in esophageal cancer. [PDF]

J Gastrointest Oncol
Gui D, Wu J, Feng Y, Lu S, Guo S, Wu K, Yan Z, Wang H, Sun H, Wang S, Liang W, Wu X.   +11 more
europepmc   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Exploring the causal relationship between gut microbiota, circulating metabolites, immune cells, and inflammation-related proteins and coronary artery calcification: A multi-omics Mendelian randomization study. [PDF]

Medicine (Baltimore)
Ma L, Xiao M, Cai S, Ding Y.
europepmc   +1 more source

Identification of Cathepsin H and Metabolic Traits as Potential Biomarkers for Lung Cancer by Mendelian Randomization and Single‐Cell Transcriptomics

Advanced Genetics, EarlyView.
This study explores the link between CTSH and lung cancer, covering global trends in lung cancer and hyperglycemia, MR analysis of CTSH and 233 metabolic traits, and scRNA analysis, along with multi‐level validation of CTSH expression in LUAD. These findings offer valuable insights into lung cancer biology and provide new perspectives for biomarker ...
Chenghu Song, Weici Liu, Zhao He, Jiwei Liu, Ruixin Wang, Lei Wu, Yize Wang, Mingfeng Zheng, Dong Tian, Wenjun Mao   +9 more
wiley   +1 more source