Results 11 to 20 of about 837,662 (281)
Comparison of the Genetic Alterations between Primary Colorectal Cancers and Their Corresponding Patient-Derived Xenograft Tissues [PDF]
Genomics & Informatics, 2018 Patient-derived xenograft (PDX) models are useful tools for tumor biology research and testing the efficacy of candidate anticancer drugs targeting the druggable mutations identified in tumor tissue.
Sang Mi Yu +2 more
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Frontiers in Genetics, 2022 Background: To decipher mutational signatures and their associations with biological implications in cutaneous melanomas (CMs), including those with a low ultraviolet (UV) signature.Materials and Methods: We applied non-negative matrix factorization (NMF)
Yoon-Seob Kim +7 more
doaj +1 more source
A Variant in Is Associated with the Risk of Ankylosing Spondylitis in Koreans [PDF]
Genomics & Informatics, 2017 Ankylosing spondylitis (AS) is a chronic autoinflammatory disease that affects the spine and sacroiliac joints. Regarding its etiology, although HLA-B27 is known to be the strongest genetic factor of AS, much evidence suggests the potential contribution ...
Sung-Min Cho +2 more
doaj +1 more source
Surgical Pathology Clinics, 2021 Polymorphous adenocarcinoma (PAC) is typically originated from the minor salivary glands and is characterized by cytology uniformity and architectural diversity. PAC commonly harbors PRKD1 E710D mutation. PAC has an excellent prognosis. However, greater than or equal to 10% papillary or greater than or equal to 30% cribriform pattern is an independent ...
Nora, Katabi, Bin, Xu
openaire +3 more sources
Validation of Customized Cancer Panel for Detecting Somatic Mutations and Copy Number Alterations [PDF]
Genomics & Informatics, 2017 Accurate detection of genomic alterations, especially druggable hotspot mutations in tumors, has become an essential part of precision medicine.
Su-Hye Choi +2 more
doaj +1 more source
A critique of avian CHD-based molecular sexing protocols illustrated by a Z-chromosome polymorphism detected in auklets [PDF]
, 2001 The sexes of non-ratite birds can be determined routinely by PCR amplification of the CHD-Z and CHD-W genes. CHD -based molecular sexing of four species of auklets revealed the presence of a polymorphism in the Z chromosome.
Burke, T. +5 more
core +1 more source
Restriction Fragment Length Polymorphism Linkage Map for Arabidopsis thaliana [PDF]
, 1988 We have constructed a restriction fragment length polymorphism linkage map for the nuclear genome of the flowering plant Arabidopsis thaliana. The map, containing 90 randomly distributed molecular markers, is physically very dense; >50% of the genome is ...
Bowman, John L. +4 more
core +1 more source
BMC Medical Genetics, 2020 Background Dedifferentiated liposarcoma (DDLPS), which accounts for an estimated 15–20% of liposarcomas, is a high-grade and aggressive malignant neoplasm, exhibiting a poor response to available therapeutic agents.
Yoon-Seob Kim +3 more
doaj +1 more source
Territory, Politics, Governance, 2017 Polymorphic borders. Territory, Politics, Governance. Conceptualizing the respatialization, rescaling and mobilization of border work is a central problem in current borders research. Traditional and ubiquitous border concepts imply a coherent state power belied by much contemporary research.
Burridge, Andrew +3 more
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Angewandte Chemie, 2005 (Figure Presented) At long last, the crystal structure of the metastable form of benzamide, whose existence has been known of for over 170 years, has finally been solved by using a combination of in situ crystallization, high-speed synchrotron X-ray powder diffraction, and global-optimization methods of structure determination (see picture).
W. I. F. David +5 more
openaire +3 more sources