Results 21 to 30 of about 651,153 (297)

POLYMORPHISM AND POLYMORPH CHARACTERISATION IN PHARMACEUTICALS

open access: yesJournal of Biomedical and Pharmaceutical Research, 2019
Polymorphism is the ability of a specific chemical compound to crystallize in more than one crystalline form. Polymorphs had a different arrangement of the molecule in the given crystal lattice and  may properties such as packing properties, thermodynamic properties, spectroscopic properties, kinetic properties, surface properties and mechanical ...
Amit Gosar   +2 more
openaire   +4 more sources

Polygenes and polymorphism

open access: yesMolecular and General Genetics MGG, 1967
Uploaded by Plazi for TaxoDros. We do not have abstracts.
S. M. W. Hosgood   +2 more
openaire   +3 more sources

Circulating MicroRNA Expression Levels Associated With Internet Gaming Disorder

open access: yesFrontiers in Psychiatry, 2018
BackgroundAddictive use of the Internet and online games is a potential psychiatric disorder termed Internet gaming disorder (IGD). Altered microRNA (miRNA) expression profiles have been reported in blood and brain tissue of patients with certain ...
Minho Lee   +19 more
doaj   +1 more source

Comparative analysis of N-acetyltransferase 2 genotyping results among patients with newly diagnosed pulmonary tuberculosis residing in the Sakha Republic (Yakutia)

open access: yesБюллетень сибирской медицины, 2021
Aim. To assess the variability of the NAT2 gene and to comparatively analyze the prevalence of NAT2 polymorphisms and acetylation types among Yakut and Russian patients newly diagnosed with pulmonary tuberculosis (TB), permanently residing in the Sakha ...
N. M. Krasnova   +13 more
doaj   +1 more source

Overexpression of TFF3 is involved in prostate carcinogenesis via blocking mitochondria-mediated apoptosis

open access: yesExperimental and Molecular Medicine, 2018
Prostate cancer: Promising protein biomarker A protein found in high levels in prostate cancer tissues could provide a biomarker and therapeutic target for the disease.
Jieying Liu   +7 more
doaj   +1 more source

Quantitative assessment of TLR4 gene polymorphisms and T2DM risk: A meta‐analysis

open access: yesMolecular Genetics & Genomic Medicine, 2020
Background Numerous studies have evaluated the association between TLR4 gene polymorphisms and T2DM risk. However, the findings were inconsistent and controversial. Methods In order to drive a more precise estimation, we carried out a meta‐analysis based
Jinzhuo Fan, Renxian Liang
doaj   +1 more source

Polymorphism and apartness. [PDF]

open access: yesNotre Dame Journal of Formal Logic, 1991
The author gives a new intuitionistic model \({\mathcal C}\) for the second- order polymorphic lambda calculus. \({\mathcal C}\) is a proper subcategory of the category \({\mathcal M}\) of realizability-valued modest sets on which earlier intuitionistic models have been constructed.
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Different inflammatory, fibrotic, and immunologic signatures between pre-fibrotic and overt primary myelofibrosis

open access: yesHaematologica
Primary myelofibrosis (PMF) is a myeloid proliferative neoplasm (MPN) characterized by bone marrow (BM) fibrosis. Pre-fibrotic PMF (pre-PMF) progresses to overt PMF.
Seung-Hyun Jung   +6 more
doaj   +1 more source

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