Results 1 to 10 of about 37,874 (304)
BMC Medical Genomics, 2022 Background Dysferlinopathy encompasses a group of rare muscular dystrophies caused by recessive mutations in the DYSF gene. The phenotype ranges from asymptomatic elevated serum creatine kinase (hyperCKemia) to selective and progressive involvement of ...
Cecilia Contreras-Cubas +7 more
doaj +2 more sources
SAGE Open Medicine, 2018 Objective: To examine the clinical utility of tumor markers in dermatomyositis/polymyositis patients in Taiwan. Method: Data were collected retrospectively from the database of Taichung Veterans General Hospital in Taiwan from 1998 to 2014.
Chong Hong Lim +6 more
doaj +2 more sources
Identification of Palmitoleic Acid Controlled by mTOR Signaling as a Biomarker of Polymyositis
Journal of Immunology Research, 2017 Polymyositis (PM) is a chronic disease characterized by muscle pain, weakness, and increase in muscle-related enzymes, accompanied with inflammations in lymphocytes.
Geng Yin +5 more
doaj +2 more sources
Polymyositis and dermatomyositis – challenges in diagnosis and management
Journal of Translational Autoimmunity, 2019 Polymyositis (PM) and dermatomyositis (DM) are different disease subtypes of idiopathic inflammatory myopathies (IIMs). The main clinical features of PM and DM include progressive symmetric, predominantly proximal muscle weakness.
Shu-Han Yang +2 more
doaj +2 more sources
Carbamoyl phosphate synthetase 1 deficiency manifested in an adult treated with prednisone for polymyositis, and cured by live-donor liver transplantation [PDF]
Molecular Genetics and Metabolism ReportsCarbamoyl phosphate synthetase 1 (CPS1) deficiency (OMIM#237300) is a rare inherited disorder due to complete or partial lack of the CPS1 enzyme. Polymyositis is a relatively rare systemic inflammatory autoimmune disease.
Kazuhiro Yokota +8 more
doaj +2 more sources
Severe Post-Viral Polymyositis after COVID-19 in Childhood: A Case Report and Literature Review [PDF]
ChildrenPolymyositis is a rarely reported complication of COVID-19 illness, especially in children. Molecular mimicry may be a cause of hyperactivated autoimmunity, leading to various clinical manifestations, including myopathies.
Jurgita Marciulynaite +2 more
doaj +2 more sources
ACR Open Rheumatology, 2022 To assess the efficacy and tolerability of tocilizumab in a multicenter, randomized, double‐blind, placebo‐controlled trial in refractory adult patients with dermatomyositis (DM) and polymyositis (PM).
C. Oddis +13 more
semanticscholar +1 more source
Scientific Reports, 2023 Dermatomyositis and polymyositis are rare, idiopathic inflammatory myopathies. Interstitial lung disease is one of the most common and potentially severe extra-muscular manifestations of dermatomyositis and polymyositis and is strongly linked to poor ...
Qingqing Hu +5 more
doaj +1 more source
BMC Cardiovascular Disorders, 2021 Background Anti-Ku is a rare antibody which can be positive in some rheumatic diseases and it might be related to cardiac involvement. Polymyositis is an inflammatory myopathy, and its cardiac involvement seldom presents as myopericarditis and anti-Ku ...
Weiping Tan +4 more
doaj +1 more source
Association between a C8orf13-BLK polymorphism and polymyositis/dermatomyositis in the Japanese population: an additive effect with STAT4 on disease susceptibility. [PDF]
PLoS ONE, 2014 BACKGROUND:Accumulating evidence has shown that several non-HLA genes are involved in the susceptibility to polymyositis/dermatomyositis. This study aimed to investigate the involvement of C8orf13-BLK, one of the strongest candidate genes for autoimmune ...
Tomoko Sugiura +7 more
doaj +1 more source