Results 81 to 90 of about 37,874 (304)

Magnetic Resonance Imaging Characteristics of Hereditary Polymyositis in the Dutch Kooiker Dog

Pets
Background: Hereditary immune-mediated polymyositis has been reported in the Kooiker dog breed, associated with a 39 kb deletion and low penetrance.
Yvet Opmeer, Stefanie Veraa, Simon Platt, Paul Mandigers   +3 more
doaj   +1 more source

Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages. [PDF]

, 2006
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Dobberstein, Bernhard, High, Stephen, Miller, Frederick W, Römisch, Karin   +3 more
core   +2 more sources

The efficacy of tacrolimus in patients with interstitial lung diseases complicated with polymyositis or dermatomyositis.

Rheumatology, 2015
OBJECTIVE Interstitial lung diseases (ILDs) complicated with PM or DM are frequently aggressive and refractory to treatment. Recently some reports have suggested the potential benefit of tacrolimus for severe ILD complicated with PM/DM.
T. Kurita, S. Yasuda, K. Oba, T. Odani, M. Kono, K. Otomo, Y. Fujieda, K. Oku, T. Bohgaki, O. Amengual, T. Horita, T. Atsumi   +11 more
semanticscholar   +1 more source

Pharmacokinetics, Safety, and Tolerability of Single‐Dose Dazukibart in Healthy Adults in China and Japan: Results From 2 Randomized, Double‐Blind, Phase 1 Studies

Clinical Pharmacology in Drug Development, Volume 14, Issue 8, Page 572-582, August 2025.
Abstract Dazukibart is a humanized monoclonal antibody selectively targeting interferon‐β. The pharmacokinetics (PK), safety, tolerability, and immunogenicity of dazukibart were evaluated in 2 double‐blind, randomized, placebo‐controlled, single‐dose, Phase 1 studies in healthy adults in China (Study 1: N = 18; dazukibart 900 mg = 15; placebo = 3) and ...
Naihan Chen, Yamato Sano, Xiaohong Wang, Shuiyi Hu, Junichi Tabira, Xin Luo, Hiroki Yoshimatsu, John Prybylski, Myron Chu, Haiyan Li, Kenji Takazawa   +10 more
wiley   +1 more source

Chronic-graft-versus-host-disease-related polymyositis: a 17-months-old child with a rare and late complication of haematopoietic stem cell transplantation.

Mediterranean Journal of Hematology and Infectious Diseases, 2020
Background: Chronic graft versus host disease (cGVHD) occurs in 20-30% of paediatric patients receiving haemopoietic stem cell transplantation (HSCT). Neuromuscular disorders such as polymyositis are considered a rare and distinctive but non-diagnostic ...
Matteo Chinello, Rita Balter, Massimiliano De Bortoli, Virginia Vitale, Ada Zaccaron, Elisa Bonetti, Paola Tonin, Gaetano Vattemi, Valeria Guglielmi, Simone Cesaro   +9 more
doaj   +1 more source

Nuclear matrix protein 2 antibody-positive adult dermatomyositis: a case report and review of the literature [PDF]

, 2020
Dermatomyositis is a clinically heterogenous inflammatory myopathy with unique cutaneous features. Myositis-specific antibodies can aid in diagnosis and anticipation of patient prognosis.
Cartron, Alexander M, Chung, Catherine, Osler, Montana, Trinidad, John C   +3 more
core  

Diclofenac Detection via Inner‐Filter Effect Using Pyridine‐Modified Triphenylene

ChemPlusChem, Volume 90, Issue 8, August 2025.
The synthesis of hexa‐pyridine triphenylene derivatives via Suzuki‐coupling reaction and their application toward the sensing of diclofenac have been studied for the first time. The 3PY and 4PY are selective for diclofenac over the other commonly prescribed pharmaceuticals and hormones tested. Triphenylene derivatives 3PY (2,3,6,7,10,11‐hexa(pyridine‐3‐
Navdeep Kajal, Amar Raj, Rajendhraprasad Tatikonda, Jan Lundell, Matti Haukka   +4 more
wiley   +1 more source

Polymyositis–dermatomyositis and infections

Autoimmunity, 2006
In genetically predisposed individuals, viruses, bacteria, or parasitic infectious agents are suspected to induce autoimmunity and/or to exacerbate the disease once the self-tolerance is broken. Although direct evidence for this association is still lacking, numerous data from animal models as well as from humans support the hypothesis of a direct ...
ZAMPIERI, SANDRA, GHIRARDELLO, ANNA, IACCARINO, LUCA, BRIANI, CHIARA, SARZI PUTTINI P, ATZENI F, ARIENTI S, TODESCO, SILVANO, DORIA, ANDREA   +8 more
openaire   +3 more sources

Revolutionizing Autoimmune Research: The Role of Caveolin‐1

Immunity, Inflammation and Disease, Volume 13, Issue 8, August 2025.
ABSTRACT Introduction Caveolins (Cav) include Cav‐1, Cav‐2, and Cav‐3, with Cav‐1 being the most studied due to its prominent role as a major component of plasma membrane caveolae. Cav‐1 is involved in a wide range of cellular functions and plays a key role in regulating signaling pathways related to immune responses and inflammation.
Yanan Gao, Liangyu Mi, Yingren Deng, Zhaojun Jia, Miaomiao Zhao, Yuting Hu, Yuli Ji, Xiaoyao He, Ke Xu   +8 more
wiley   +1 more source

The Role of Repeat Skeletal Muscle Biopsy: Indications, Yield and Outcomes

Muscle &Nerve, Volume 72, Issue 2, Page 217-223, August 2025.
ABSTRACT Introduction/Aims Muscle biopsy performed to investigate weakness and/or pain may be nondiagnostic and prompt repeat biopsy. We determined the indications and yield of rebiopsy. Methods Patients who underwent > 1 muscle biopsy (South Australia, 2000–2023) were identified.
Thomas Khoo, Sarah Saxon, Barbara Koszyca, Bernice Gutschmidt, Vidya Limaye   +4 more
wiley   +1 more source