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Battle of polymyxin induced nephrotoxicity: Polymyxin B versus colistin
International Journal of Antimicrobial AgentsObjectives: Nephrotoxicity is the most serious and common adverse effect that limits the use of polymyxins. This study compared polymyxin E (colistin) and polymyxin B regarding drug-related nephrotoxicity.
Melek Kurtaran +2 more
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American Journal of Health-System Pharmacy, 1948
In May 1947, Benedict and Langlykke 1 reported that sterile culture filtrates of Bacillus polymyxa in dilutions of 1:1,000 inhibited the growth of Brucella bronchiseptica in culture. Shortly after this report, Stansly, Shepherd and White 2 independently described the isolation of an antibiotic substance from B.
Emanuel B. Schoenbach +3 more
+6 more sources
In May 1947, Benedict and Langlykke 1 reported that sterile culture filtrates of Bacillus polymyxa in dilutions of 1:1,000 inhibited the growth of Brucella bronchiseptica in culture. Shortly after this report, Stansly, Shepherd and White 2 independently described the isolation of an antibiotic substance from B.
Emanuel B. Schoenbach +3 more
+6 more sources
A Review of the Clinical Pharmacokinetics of Polymyxin B
Antibiotics, 2019 Polymyxin B remains an antibiotic of last resort because of its toxicities. Although newer therapies are becoming available, it is anticipated that resistance to these agents will continue to emerge, and understanding the safest and most efficacious ...
Sean N Avedissian +2 more
exaly +2 more sources
Current Medicinal Chemistry, 2013
Polymyxins are polypeptide antibiotics, with a primary effect of membrane damaging due to their selective binding to the lipopolysaccharide of Gram-negative bacteria. Their nephro- and neurotoxic side effects limited their use, however, in the last decade the emergence of multidrug-resistant Gram-negative bacteria led to the reintroduction of ...
B, Kadar, B, Kocsis, K, Nagy, D, Szabo
openaire +2 more sources
Polymyxins are polypeptide antibiotics, with a primary effect of membrane damaging due to their selective binding to the lipopolysaccharide of Gram-negative bacteria. Their nephro- and neurotoxic side effects limited their use, however, in the last decade the emergence of multidrug-resistant Gram-negative bacteria led to the reintroduction of ...
B, Kadar, B, Kocsis, K, Nagy, D, Szabo
openaire +2 more sources
Archives of Pediatrics & Adolescent Medicine, 1984
Sir .—It was with a mixture of interest and personal chagrin that I read the article by Larter et al 1 on polymyxin B sulfate and pertussis vaccine—interest because I have been a sometime advocate of this particular application of the endotoxin-inactivating activity of polymyxin B, but chagrin that, in this narrow field, reference to my own publication
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Sir .—It was with a mixture of interest and personal chagrin that I read the article by Larter et al 1 on polymyxin B sulfate and pertussis vaccine—interest because I have been a sometime advocate of this particular application of the endotoxin-inactivating activity of polymyxin B, but chagrin that, in this narrow field, reference to my own publication
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Archives of Dermatology, 1963
To the Editor : In the June, 1961, issue of theArchives of Dermatology, G. Asboe-Hansen, M.D., Copenhagen, Denmark, reported the therapeutical essay of polymyxin B (Pfizer) in a case of generalized mastocytosis. We tried this treatment, utilizing disyncran as a cover against histamine liberation, in a case of urticaria pigmentosa which had resisted ...
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To the Editor : In the June, 1961, issue of theArchives of Dermatology, G. Asboe-Hansen, M.D., Copenhagen, Denmark, reported the therapeutical essay of polymyxin B (Pfizer) in a case of generalized mastocytosis. We tried this treatment, utilizing disyncran as a cover against histamine liberation, in a case of urticaria pigmentosa which had resisted ...
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Nomenclature of Polymyxin Antibiotics
Nature, 1949POLYMYXIN is a term introduced by Stansly, Shepherd and White1 for an antibiotic substance elaborated by Bacillus polymyxa.
P G, STANSLY, G, BROWNLEE
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2000
Abstract Polymyxin B and polymyxin E (colistin) are microorganism derived antibiotics effective against Gram-negative bacteria. Although parenteral administration is accompanied by nephrotoxicity and neurotoxicity, intravenous colistin is effective in treating acute respiratory exacerbations associated with Pseudomonas aeruginosa in ...
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Abstract Polymyxin B and polymyxin E (colistin) are microorganism derived antibiotics effective against Gram-negative bacteria. Although parenteral administration is accompanied by nephrotoxicity and neurotoxicity, intravenous colistin is effective in treating acute respiratory exacerbations associated with Pseudomonas aeruginosa in ...
openaire +1 more source