Results 91 to 100 of about 40,696 (222)

Field effect transistor biosensors for healthcare monitoring

Interdisciplinary Medicine, Volume 2, Issue 4, October 2024.
Amidst the growing need for healthcare monitoring, field effect transistor (FET) biosensors stand out for their high sensitivity and rapid detection capabilities. The review delves into sensor design and operational principles highlighting their application in biomarker detection for diseases.
Zhicheng Zhang, Jing‐Jing Hu, Shijun Lin, Jiajun Wu, Fan Xia, Xiaoding Lou   +5 more
wiley   +1 more source

A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells

Small Science, Volume 4, Issue 10, October 2024.
Growing demand for meat and environmental concerns are driving the search for sustainable alternatives for meat production. Cultured meat from animal stem cells, particularly insect stem cells, is emerging as an efficient, economical, and environmentally friendly option.
Fabiana Giglio, Carmen Scieuzo, Sofia Ouazri, Valentina Pucciarelli, Dolores Ianniciello, Sophia Letcher, Rosanna Salvia, Ambrogio Laginestra, David L. Kaplan, Patrizia Falabella   +9 more
wiley   +1 more source

Strategies for Detecting Aminoacylation and Aminoacyl‐tRNA Editing in vitro and in Cells

Israel Journal of Chemistry, Volume 64, Issue 8-9, September 2024.
Abstract Aminoacyl‐tRNA synthetases (aaRSs) maintain translational fidelity by ensuring the formation of correct aminoacyl‐tRNA pairs. Numerous point mutations in human aaRSs have been linked to disease phenotypes. Structural studies of aaRSs from human pathogens encoding unique domains support these enzymes as potential candidates for therapeutics ...
Rylan R. Watkins, Arundhati Kavoor, Karin Musier‐Forsyth   +2 more
wiley   +1 more source

Bottom‐Up Synthesized Glucan Materials: Opportunities from Applied Biocatalysis

Advanced Materials, Volume 36, Issue 27, July 4, 2024.
Linear d‐glucans, simple yet versatile polysaccharides, shape nanostructures crucial for biomaterial development. Shifting from top‐down to bottom‐up synthesis using natural and engineered enzymes provides meticulous control over polymer structures, fostering diversification for macromolecular materials.
Chao Zhong, Bernd Nidetzky
wiley   +1 more source

Single‐Molecule Electrical Profiling of Peptides and Proteins

Advanced Science, Volume 11, Issue 28, July 24, 2024.
This work presents a timely overview of the prominent research progress in peptide and protein‐related studies through single‐molecule electrical techniques, including single‐molecule junction, single‐molecule field‐effect transistor (FET), and nanopore.
Hongyu Ju, Li Cheng, Mengmeng Li, Kunrong Mei, Suhang He, Chuancheng Jia, Xuefeng Guo   +6 more
wiley   +1 more source

Complexation of DNA with Cationic Surfactant [PDF]

, 1999
Transfection of an anionic polynucleotide through a negatively charged membrane is an important problem in genetic engineering. The direct association of cationic surfactant to DNA decreases the effective negative charge of the nucleic acid, allowing the DNA-surfactant complex to approach a negatively charged membrane.
arxiv   +1 more source

Stacking and Hydrogen Bonding. DNA Cooperativity at Melting [PDF]

Biopolymers 75, 434 (2004), 2004
By taking into account base-base stacking interactions we improve the Generalized Model of Polypeptide Chain (GMPC). Based on a one-dimensional Potts-like model with many-particle interactions, the GMPC describes the helix-coil transition in both polypeptides and polynucleotides.
arxiv   +1 more source

The number of domains in the ribosomal protein S1 as a hallmark of the phylogenetic grouping of bacteria.

PLoS ONE, 2019
The family of ribosomal proteins S1 contains about 20% of all bacterial proteins including the S1 domain. An important feature of this family is multiple copies of structural domains in bacteria, the number of which changes in a strictly limited range ...
Andrey V Machulin, Evgenia I Deryusheva, Olga M Selivanova, Oxana V Galzitskaya   +3 more
doaj   +1 more source

The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-N-acetylglucosamine (PNAG) production in Escherichia coli C

BMC Microbiology, 2012
Background Transition from planktonic cells to biofilm is mediated by production of adhesion factors, such as extracellular polysaccharides (EPS), and modulated by complex regulatory networks that, in addition to controlling production of adhesion ...
Carzaniga Thomas, Antoniani Davide, Dehò Gianni, Briani Federica, Landini Paolo   +4 more
doaj   +1 more source

Binding of Carminomycin to synthetic polyribonucleotides poly(A) and poly(U): absorption and polarized fluorescence study [PDF]

Biophysical Bulletin 488(1)(2000)56-59.(in Ukrainian), 2020
Binding of anthracycline antibiotic carminomycin (CM) to synthetic polyribonucleotides poly(A) and poly(U) was studied in solution of low ionic strength in a wide phosphate-to-dye (P/D) range using absorption and polarized fluorescence spectroscopy. Two different modes of CM binding to the ss-polynucleotides have been identified.
arxiv