Results 91 to 100 of about 43,981 (239)

Severo Ochoa and the Biomedical Sciences in Spain under Franco, 1959-1975 [PDF]

open access: yes, 2000
The influence of Severo Ochoa in the establishment of biochemistry and molecular biology in Spain is the central topic of this essay. From the time he was awarded the Nobel Prize in Physiology or Medicine in 1959, Ochoa's links with Spanish scientists ...
Modigell, Michael   +3 more
core   +1 more source

Field effect transistor biosensors for healthcare monitoring

open access: yesInterdisciplinary Medicine, Volume 2, Issue 4, October 2024.
Amidst the growing need for healthcare monitoring, field effect transistor (FET) biosensors stand out for their high sensitivity and rapid detection capabilities. The review delves into sensor design and operational principles highlighting their application in biomarker detection for diseases.
Zhicheng Zhang   +5 more
wiley   +1 more source

The RNA processing enzyme polynucleotide phosphorylase negatively controls biofilm formation by repressing poly-N-acetylglucosamine (PNAG) production in Escherichia coli C

open access: yesBMC Microbiology, 2012
Background Transition from planktonic cells to biofilm is mediated by production of adhesion factors, such as extracellular polysaccharides (EPS), and modulated by complex regulatory networks that, in addition to controlling production of adhesion ...
Carzaniga Thomas   +4 more
doaj   +1 more source

Rat liver mitochondrial polynucleotide phosphorylase

open access: yesFEBS Letters, 1971
We have recently isolated, partially purified and demonstrated the specificity of a polynucleotide phosphorylase from crude guinea-pig liver nuclei [ 1,2] The enzyme was associated with membrane lipids and catalysed the phosphorolysis of polyribonucleotides to ribonucleoside diphosphates.
Yew Phew See, P. S. Fitt
openaire   +3 more sources

A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells

open access: yesSmall Science, Volume 4, Issue 10, October 2024.
Growing demand for meat and environmental concerns are driving the search for sustainable alternatives for meat production. Cultured meat from animal stem cells, particularly insect stem cells, is emerging as an efficient, economical, and environmentally friendly option.
Fabiana Giglio   +9 more
wiley   +1 more source

Regulatory Mechanisms of Exoribonuclease PNPase and Regulatory Small RNA on T3SS of Dickeya dadantii

open access: yesMolecular Plant-Microbe Interactions, 2010
The type III secretion system (T3SS) is an essential virulence factor for many bacterial pathogens. Polynucleotide phosphorylase (PNPase) is one of the major exoribonucleases in bacteria and plays important roles in mRNA degradation, tRNA processing, and
Quan Zeng   +3 more
doaj   +1 more source

Strategies for Detecting Aminoacylation and Aminoacyl‐tRNA Editing in vitro and in Cells

open access: yesIsrael Journal of Chemistry, Volume 64, Issue 8-9, September 2024.
Abstract Aminoacyl‐tRNA synthetases (aaRSs) maintain translational fidelity by ensuring the formation of correct aminoacyl‐tRNA pairs. Numerous point mutations in human aaRSs have been linked to disease phenotypes. Structural studies of aaRSs from human pathogens encoding unique domains support these enzymes as potential candidates for therapeutics ...
Rylan R. Watkins   +2 more
wiley   +1 more source

Arabidopsis chloroplast quantitative editotype [PDF]

open access: yes, 2013
Chloroplast C-to-U RNA editing is an essential post-transcriptional process. Here we analyzed RNA editing in Arabidopsis thaliana using strand-specific deep sequencing datasets from the wild-type and a mutant defective in RNA 3′ end maturation.
Castandet, Benoit   +3 more
core   +1 more source

The number of domains in the ribosomal protein S1 as a hallmark of the phylogenetic grouping of bacteria.

open access: yesPLoS ONE, 2019
The family of ribosomal proteins S1 contains about 20% of all bacterial proteins including the S1 domain. An important feature of this family is multiple copies of structural domains in bacteria, the number of which changes in a strictly limited range ...
Andrey V Machulin   +3 more
doaj   +1 more source

Bottom‐Up Synthesized Glucan Materials: Opportunities from Applied Biocatalysis

open access: yesAdvanced Materials, Volume 36, Issue 27, July 4, 2024.
Linear d‐glucans, simple yet versatile polysaccharides, shape nanostructures crucial for biomaterial development. Shifting from top‐down to bottom‐up synthesis using natural and engineered enzymes provides meticulous control over polymer structures, fostering diversification for macromolecular materials.
Chao Zhong, Bernd Nidetzky
wiley   +1 more source

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