Results 91 to 100 of about 17,823 (227)

Prediction of Proliferation Rate of Pre‐Osteoblasts Using Raman Spectroscopy and Machine Learning Models

Journal of Raman Spectroscopy, EarlyView.
The main processes involved in predicting the pre–osteoblast proliferation rate using Raman spectroscopy and machine learning. ABSTRACT This novel study focuses on using Raman spectroscopy and machine learning (ML) models to forecast the murine pre‐osteoblast (OB) proliferation rate.
Sai S. Sudha, Angshuman Baradwaz, Ahmad Y. Javaid, Ambalangodage C. Jayasuriya   +3 more
wiley   +1 more source

The transcription factor c-Myc suppresses MiR-23b and MiR-27b transcription during fetal distress and increases the sensitivity of neurons to hypoxia-induced apoptosis. [PDF]

PLoS ONE, 2015
Previous studies reported that the expression of miR-23b-27b cluster was downregulated in embryonic brain cortices during hypoxia-induced neuronal apoptosis. However, the mechanism underlying this downregulation is not completely understood.
Qun Chen, Fan Zhang, Yanbo Wang, Zhengya Liu, Anyang Sun, Ke Zen, Chen-yu Zhang, Qipeng Zhang   +7 more
doaj   +1 more source

ENZYMATIC SYNTHESIS OF POLYNUCLEOTIDES

Journal of Biological Chemistry, 1957
SUMMARY The relative activity toward different nucleoside diphosphates remains essentially unchanged after 500-fold purification of polynucleotide phosphorylase of Azotobacter v&elan&i suggesting that a single enzyme is involved. The purified enzyme, virtually free of nuclease, contains small amounts of an oligoribonucleotide (with adenine, guanine ...
Matthys Staehelin, Severo Ochoa, Dewey O. Brummond   +2 more
openaire   +3 more sources

Surface Localized Coacervation Controlled by Bioactive Nanoarchitectonic Polyelectrolyte Multilayers

Small, EarlyView.
Using enzymatically active nanoarchitectured polyelectrolyte multilayers (PEMs), localized liquid–liquid phase separation can be directed from a so‐modified surface. In the presence of urea, PEM‐containing urease layers generate a pH gradient near the surface resulting in the self‐coacervation of a model peptide‐based coacervator.
Jean‐Yves Runser, Shahaji H. More, Robin Weiss, Christophe Contal, Alexis Bigo‐Simon, Maximilien Masquelier, Vincent Ball, Bernard Senger, Caroline Bertagnolli, Pierre Schaaf, Loïc Jierry   +10 more
wiley   +1 more source

Study on Interaction of Cationic Porphyrazine with Synthetic Polynucleotides

Analytical Cellular Pathology, 2013
Interactions of cationic tetrakis (N, N′, N″, N‴- tetramethyltetra-3, 4-pyridinoporphyrazinatozinc (II) (Zn (tmtppa)) with synthetic polynucleotides, poly (G-C) and poly (A-T), and calf thymus DNA have been characterized in 7.5 mM phosphate buffer of pH ...
Hamid Dezhampanah, Soghra Fyzolahjani
doaj   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

Small, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai, Dhwani Rana, Mitali Patel, Neha Bajwa, Rajendra Prasad, Lalitkumar K. Vora   +5 more
wiley   +1 more source

Viral Evolution and Adaptation as a Multivariate Branching Process [PDF]

, 2011
In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius, Schuster and Sigmund ("Polynucleotide evolution and branching processes", Bull. Math. Biol. 46 (1985) 239-262), in
arxiv   +1 more source

Interaction of Nucleosides and Related Compounds with Nucleic Acids as Indicated by the Change of Helix-Coil Transition Temperature [PDF]

, 1962
A series of compounds has been tested for effectiveness in lowering the melting temperature of poly A and of thymus DNA. The order of increasing activity was found to be: adonitol, methyl riboside (both negligible) < cyclohexanol < phenol, pyrimidine ...
Helmkamp, G. K., Sander, C., T'so, Paul O. P.   +2 more
core   +1 more source

Toward Automated DNA Nanoprinting: Advancing the Synthesis of Covalently Branched DNA

Small Methods, EarlyView.
A streamlined synthesis method for covalently branched DNA is developed, laying the foundation for future automated DNA printing devices. Different DNA strands can be covalently transferred to various small molecules, including aromatics and functional porphyrins.
Fangzhou Zhao, Daniel Saliba, Jathavan Asohan, Hanadi F. Sleiman   +3 more
wiley   +1 more source

U.S. Patent Literature Survey of Agrobacterium-Mediated Transformation of Sweet Potato (Ipomoea Batatas) [PDF]

, 2007
A team of researchers and patent information scientists at Franklin Pierce Law Center were asked to evaluate the patent and literature landscape related to the Agrobacterium-mediated transformation in sweet potato with respect to the U.S.
Cavicchi, Jon R., Kowalski, Stanley P., Murthy, J. Jaya, Vartak, Rahul R.   +3 more
core   +1 more source