Results 81 to 90 of about 11,904 (209)

On the interaction of doxorubicin with polynucleotides

, 2014
The interaction of doxorubicin (DX) with model polynucleotides poly(dG-dC)·poly(dG-dC) (polyGC), poly(dA-dT)·poly(dA-dT) (poly-AT), and calf thymus DNA has been studied by several spectroscopic techniques in phosphate buffer aqueous solutions.
GENNARO, Giuseppe, Marta Airoldi, GIULIANI RICCI, Anna Maria, Giampaolo Barone, Anna Maria Giuliani, AIROLDI, Marta, GIUSTINI, Mauro, Giuseppe Gennaro, GIUSTINI, M., Mauro Giustini, BARONE, Giampaolo   +10 more
core   +1 more source

Spontaneous Entrapment of Polynucleotides upon Electrostatic Interaction with Ethanol-Destabilized Cationic Liposomes [PDF]

, 2001
This study describes the effect of ethanol and the presence of poly(ethylene) glycol (PEG) lipids on the interaction of nucleotide-based polyelectrolytes with cationic liposomes.
Deirdre Mcintosh, McIntosh, D., Scherrer, P., Holger Stark, Peter Scherrer, Wong, Kim F., Scherrer, Peter, Semple, S. C., McIntosh, Deirdre, Wong, K. F., Louie, L., Semple, Sean C., Cullis, Pieter R., Sean C. Semple, Pieter R. Cullis, Semple, S., Stark, H., Maurer, Norbert, Wong, K., Norbert Maurer, Stark, Holger, Louie, Lenore, Lenore Louie, Wong, T., Maurer, N., Cullis, P. R., Wong, Tabitha, Tabitha Wong, Cullis, P., Kim F. Wong   +29 more
core   +1 more source

The PRIME trial: An investigator‐initiated, multicentre, phase II study of the poly(ADP‐ribose) polymerase inhibitor olaparib in isocitrate dehydrogenase (IDH)‐mutated relapsed/refractory acute myeloid leukaemia and myelodysplastic syndromes

British Journal of Haematology, EarlyView.
Rory M. Shallis, Jennifer VanOudenhove, Namrata Chandhok, Justin Watts, Deepa Jeyakumar, Daniel R. Reed, Jan Phillip Bewersdorf, Diane Durecki, Scott Boerner, Richard F. Little, Steven D. Gore, Jing Li, Xun Bao, Li Chen, Sayak Ghatak, Thomas Prebet, Ranjit S. Bindra, Amer M. Zeidan, Stephanie Halene   +18 more
wiley   +1 more source

Synthesis and Properties of Potentially Antiviral Polynucleotides.

, 1978
Synthetic polynucleotides have been shown to exhibit antiviral properties in a variety of biological systems. This thesis describes the synthesis and properties of some novel and potentially active compounds.
Bell, L. D.
core  

The promising potential of polynucleotide injections for knee osteoarthritis: A systematic review of literature and meta‐analysis of randomized control trials

Journal of Experimental Orthopaedics
Purpose The present study aims to synthesize and evaluate the evidence on the effectiveness of intra‐articular polynucleotides (PNs) for knee osteoarthritis (OA). Methods In March 2024, we searched MEDLINE, Emcare, Web of Science and Cochrane Library for
Joseph Elphingstone, Michael Bowler, Pietro Conte, Giuseppe Anzillotti, Elizaveta Kon   +4 more
doaj   +1 more source

New polynucleotides, having diagnostic and therapeutic applications - include one or more phosphoro-di:thioate inter-nucleotide linkages

, 1998
Polynucleotides, in which all the internucleotide linkages between individual nucleotide groups in the polynucleotide are phosphorodithioate internucleotide linkages, are new.
Nielsen, John, Yau, E, CARUTHERS, M H,, Brill, W, MA, M   +4 more
core  

Ribozyme Activity of RNA Nonenzymatically Polymerized from 3′,5′-Cyclic GMP

Entropy, 2013
3′,5′-Cyclic GMP spontaneously nonenzymatically polymerizes in a base-catalyzed reaction affording G oligonucleotides. When reacted with fully or partially sequence-complementary RNA (oligo C), the abiotically generated oligo G RNA displays a typical ...
Samanta Pino, Giovanna Costanzo, Alessandra Giorgi, Jiří Šponer, Judit E. Šponer, Ernesto Di Mauro   +5 more
doaj   +1 more source

Ablation of keratan sulfate accelerates early phase pathogenesis of ALS.

PLoS ONE, 2013
Biopolymers consist of three major classes, i.e., polynucleotides (DNA, RNA), polypeptides (proteins) and polysaccharides (sugar chains). It is widely accepted that polynucleotides and polypeptides play fundamental roles in the pathogenesis of ...
Kenichi Hirano, Tomohiro Ohgomori, Kazuyoshi Kobayashi, Fumiaki Tanaka, Tomohiro Matsumoto, Takamitsu Natori, Yukihiro Matsuyama, Kenji Uchimura, Kazuma Sakamoto, Hideyuki Takeuchi, Akihiro Hirakawa, Akio Suzumura, Gen Sobue, Naoki Ishiguro, Shiro Imagama, Kenji Kadomatsu   +15 more
doaj   +1 more source

Mesoscopic irreversible thermodynamics of aging kinetics of alpha polypeptides [DNA] under various constraints: Special reference to the simple spring mechanics

AIP Advances
The mesoscopic irreversible thermodynamic treatment of α-polypeptides and the helical polynucleotides (DNA) furnishes two sets of analytical expressions, which allow us not only to analyze the reversible force–extension experiments performed by atomic ...
Tarik Omer Ogurtani
doaj   +1 more source

A Histological Assessment of Bone Augmentation of a Knife-Edge Alveolar Ridge by the Umbrella-Screw Tent Technique Using a Xenograft Compound with Polynucleotide-Hyaluronic Acid—A Case Report

Applied Sciences
Objectives: Horizontal ridge augmentation remains a clinical challenge due to limitations in terms of spatial maintenance, graft stability and predictability of new bone formation.
Julia Lubauer, Algirdas Puišys, Robert Sader, Florian Rathe, Markus Schlee   +4 more
doaj   +1 more source