Results 61 to 70 of about 11,904 (209)

In Vitro Evidence for Oral Soft Tissue Regenerative Effects of a Polynucleotide–Hyaluronan Formulation

Clinical and Experimental Dental Research
Objectives We aimed to investigate the effects of a polynucleotide–hyaluronan (PN–HA) formulation on human palatal fibroblasts (HPFs) and oral epithelial cells (OKF6/TERT‐2) to assess its potential application in oral soft tissue reconstructive ...
Ina Mladenova, Xiaoqing Song, Cristina Nica, Anton Sculean, Maria B. Asparuhova   +4 more
doaj   +1 more source

Polynucleotide HPT^TM-Based Hydrogels Exhibit Scavenging Activity Against Reactive Oxygen Species

Antioxidants
This study investigates the scavenger activity of Polynucleotide High Purification Technology (PN HPTTM), alone or in combination with hyaluronic acid (PN HPTTM + HA) against oxidative stress induced by hydrogen peroxide (H2O2). Since oxidative stress is
Maria Teresa Colangelo, Silvana Belletti, Stefano Guizzardi, Carlo Galli   +3 more
doaj   +1 more source

Origin of the Genetic Code Is Found at the Transition between a Thioester World of Peptides and the Phosphoester World of Polynucleotides

Life, 2019
The early metabolism arising in a Thioester world gave rise to amino acids and their simple peptides. The catalytic activity of these early simple peptides became instrumental in the transition from Thioester World to a Phosphate World.
Hyman Hartman, Temple F. Smith
doaj   +1 more source

Sequence specific binding of beta carboline alkaloid harmalol with deoxyribonucleotides: binding heterogeneity, conformational, thermodynamic and cytotoxic aspects. [PDF]

PLoS ONE, 2014
Base dependent binding of the cytotoxic alkaloid harmalol to four synthetic polynucleotides, poly(dA).poly(dT), poly(dA-dT).poly(dA-dT), poly(dG).poly(dC) and poly(dG-dC).poly(dG-dC) was examined by various photophysical and calorimetric studies, and ...
Sarita Sarkar, Prateek Pandya, Kakali Bhadra   +2 more
doaj   +1 more source

Report of Adverse Events Associated With Cutaneous Procedures: Update From the CAPER Registry

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objectives To systematically evaluate submissions to the CAPER database by analyzing procedural context, characteristics of reported adverse events (AEs), and provider involvement in order to identify patterns with potential implications for patient safety.
Sabrina S. Smith, Michael D. Yi, Elizabeth Zhang, Joycie Chang, Thanvi Gullapalli, Doroteja Dragovic, Vanessa J. Lazaro‐Camp, Ashish C. Bhatia, Arisa Ortiz, Murad Alam   +9 more
wiley   +1 more source

QUINACRINE - SPECTROSCOPIC PROPERTIES AND INTERACTIONS WITH POLYNUCLEOTIDES

, 1993
The acridine dye quinacrine and its interactions with calf thymus DNA, poly(dA-dT).poly(dA-dT), and poly(dG-dC).poly(dG-dC) were studied by light absorption, linear dichroism, and fluorescence spectroscopy.
Doglia, S. M., B. Nordén, B. Albinsson, Hiort, Catharina, Hiort, Catharina,, S. M. Doglia, C. Hiort, Nord\ue9n, Bengt, Graslund, A., Albinsson, Bo,, Nordén, Bengt, A. Gräslund, Nordén, Bengt,, Albinsson, Bo   +13 more
core   +1 more source

Human APOBEC3G suppresses homologous recombination and LIG4‐independent end joining in DNA double‐strand break repair

The FEBS Journal, EarlyView.
Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito, Miori Murayama, Usaki Arai, Sekifumi Akatsu, Ami Yamamoto, Misaki Kadoguchi, Noritaka Adachi   +6 more
wiley   +1 more source

ESR of Cu2+ bound to polynucleotides and derivatives [PDF]

, 1971
Binding of Cu2+ to polynucleotides has been found to occur at 1 Cu/5 polymer P and at similar molar ratios of copper to selected nucleic acid derivatives.
Rieber, M., M. Wust, Wust, M., M. Rieber, G. Bemski, Bemski, G.   +5 more
core   +1 more source

Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next‐Generation Biomaterials

Journal of Periodontal Research, EarlyView.
Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia, M. Diba, B. T. Yilmaz, Jae‐Kook Cha, D. T. Wu, D. J. Mooney   +5 more
wiley   +1 more source

Patent landscape analysis of inventions based on plant genetic resources for food and agriculture and related digital sequence information

The Journal of World Intellectual Property, EarlyView.
Abstract This article provides an overview of the patent landscape in relation to PGRFA‐based inventions involving naturally occurring (“native”) traits and related Digital Sequence Information/Genetic Sequence Data (DSI/GSD). In particular, it focuses on the potential of patent claims to limit others' uses of PGRFA and related DSI/GSD on which the ...
Claudio Chiarolla, Michael Andreas Kock, Paul Oldham, Michael Halewood, Isabel López Noriega, Jasmine Kindness   +5 more
wiley   +1 more source