Results 101 to 110 of about 17,878 (213)

Ablation of keratan sulfate accelerates early phase pathogenesis of ALS.

open access: yesPLoS ONE, 2013
Biopolymers consist of three major classes, i.e., polynucleotides (DNA, RNA), polypeptides (proteins) and polysaccharides (sugar chains). It is widely accepted that polynucleotides and polypeptides play fundamental roles in the pathogenesis of ...
Kenichi Hirano   +15 more
doaj   +1 more source

Concentration and isolation of DNA from biological fluids by agarose gel isotachophoresis

open access: yesBioTechniques, 2005
Isotachophoresis is an electrophoretic method of separation of charged substances. The method is characterized by a discontinuous buffer system, constant velocity of separated molecules, and the distribution of separated components in the form of narrow ...
Valentina N. Kondratova   +3 more
doaj   +1 more source

Stereoselective formation of a 2 prime (3 prime)- aminoacyl ester of a nucleotide [PDF]

open access: yes
Reaction of DL-series and adenosine-5-phosphorimidazolide in the presence of adenosine-5'-(0-methylphosphate) and imidazole resulted in the stereoselective synthesis of the aminoacyl nucleotide ester, 2'(3')-0-seryl-adenosine-5'-(0-methylphosphate).
Weber, A. L.
core   +1 more source

Method for creating polynucleotide and polypeptide sequences [PDF]

open access: yes, 2003
The invention provides methods for evolving a polynucleotide toward acquisition of a desired property. Such methods entail incubating a population of parental polynucleotide variants under conditions to generate annealed polynucleotides comprising ...
Arnold, Frances   +2 more
core   +1 more source

The origin of biological macromolecules on the earth. The hypothesis of inorganic template [PDF]

open access: yes
Studies about the origin of life are reviewed. The nonrandom organization of organelles is discussed from a structural and functional point of view. After postulating that the origin of biomacromolecules was not a random event, the paper develops the ...
Lu, T. S.
core   +1 more source

Molecular evolution research Annual report [PDF]

open access: yes
Amino acid syntheses by heating formaldehyde and ammonia mixtures in molecular evolution ...

core   +1 more source

Structure of non-viral vectors based on cholesteric liquid-crystal polymers by SAXS [PDF]

open access: yes, 2016
Cationic polymers, at physiological pH, are used to condense anionic nucleic acids, as healing agent, into nano-sized particle-like complexes called “polyplexes”, through self-assembly driven by electrostatic interactions. By compressing DNA molecules to
Fayos, José   +2 more
core  

Mesoscopic irreversible thermodynamics of aging kinetics of alpha polypeptides [DNA] under various constraints: Special reference to the simple spring mechanics

open access: yesAIP Advances
The mesoscopic irreversible thermodynamic treatment of α-polypeptides and the helical polynucleotides (DNA) furnishes two sets of analytical expressions, which allow us not only to analyze the reversible force–extension experiments performed by atomic ...
Tarik Omer Ogurtani
doaj   +1 more source

The Origins of Life: What One Needs to Know

open access: yesZygon, 1997
Many solar systems in the universe may be expected to contain rocky planets that have accreted organic compounds. These compounds are likely to be universally found. In addition, the chemistry of sulfur, phosphorus, and iron is likely to dominate energy
doaj   +2 more sources

A Histological Assessment of Bone Augmentation of a Knife-Edge Alveolar Ridge by the Umbrella-Screw Tent Technique Using a Xenograft Compound with Polynucleotide-Hyaluronic Acid—A Case Report

open access: yesApplied Sciences
Objectives: Horizontal ridge augmentation remains a clinical challenge due to limitations in terms of spatial maintenance, graft stability and predictability of new bone formation.
Julia Lubauer   +4 more
doaj   +1 more source

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