Results 91 to 100 of about 9,001 (206)

Synthesis and Properties of Potentially Antiviral Polynucleotides.

, 2018
Synthetic polynucleotides have been shown to exhibit antiviral properties in a variety of biological systems. This thesis describes the synthesis and properties of some novel and potentially active compounds.
Bell, L. D.
core  

Synthesis and Properties of Potentially Antiviral Polynucleotides.

, 1978
Synthetic polynucleotides have been shown to exhibit antiviral properties in a variety of biological systems. This thesis describes the synthesis and properties of some novel and potentially active compounds.
Bell, L. D.
core  

Ablation of keratan sulfate accelerates early phase pathogenesis of ALS.

PLoS ONE, 2013
Biopolymers consist of three major classes, i.e., polynucleotides (DNA, RNA), polypeptides (proteins) and polysaccharides (sugar chains). It is widely accepted that polynucleotides and polypeptides play fundamental roles in the pathogenesis of ...
Kenichi Hirano, Tomohiro Ohgomori, Kazuyoshi Kobayashi, Fumiaki Tanaka, Tomohiro Matsumoto, Takamitsu Natori, Yukihiro Matsuyama, Kenji Uchimura, Kazuma Sakamoto, Hideyuki Takeuchi, Akihiro Hirakawa, Akio Suzumura, Gen Sobue, Naoki Ishiguro, Shiro Imagama, Kenji Kadomatsu   +15 more
doaj   +1 more source

New polynucleotides, having diagnostic and therapeutic applications - include one or more phosphoro-di:thioate inter-nucleotide linkages

, 1998
Polynucleotides, in which all the internucleotide linkages between individual nucleotide groups in the polynucleotide are phosphorodithioate internucleotide linkages, are new.
Nielsen, John, Yau, E, CARUTHERS, M H,, Brill, W, MA, M   +4 more
core  

ESR of Cu2+ bound to polynucleotides and derivatives

, 1971
Binding of Cu2+ to polynucleotides has been found to occur at 1 Cu/5 polymer P and at similar molar ratios of copper to selected nucleic acid derivatives.
Rieber, M., M. Wust, Wust, M., M. Rieber, G. Bemski, Bemski, G.   +5 more
core   +1 more source

Concentration and isolation of DNA from biological fluids by agarose gel isotachophoresis

BioTechniques, 2005
Isotachophoresis is an electrophoretic method of separation of charged substances. The method is characterized by a discontinuous buffer system, constant velocity of separated molecules, and the distribution of separated components in the form of narrow ...
Valentina N. Kondratova, Ol'ga I. Serd'uk, Valery P. Shelepov, Anatoly V. Lichtenstein   +3 more
doaj   +1 more source

Mesoscopic irreversible thermodynamics of aging kinetics of alpha polypeptides [DNA] under various constraints: Special reference to the simple spring mechanics

AIP Advances
The mesoscopic irreversible thermodynamic treatment of α-polypeptides and the helical polynucleotides (DNA) furnishes two sets of analytical expressions, which allow us not only to analyze the reversible force–extension experiments performed by atomic ...
Tarik Omer Ogurtani
doaj   +1 more source

Spontaneous Entrapment of Polynucleotides upon Electrostatic Interaction with Ethanol-Destabilized Cationic Liposomes

, 2001
This study describes the effect of ethanol and the presence of poly(ethylene) glycol (PEG) lipids on the interaction of nucleotide-based polyelectrolytes with cationic liposomes.
Deirdre Mcintosh, McIntosh, D., Scherrer, P., Holger Stark, Peter Scherrer, Wong, Kim F., Scherrer, Peter, Semple, S. C., McIntosh, Deirdre, Wong, K. F., Louie, L., Semple, Sean C., Cullis, Pieter R., Sean C. Semple, Pieter R. Cullis, Semple, S., Stark, H., Maurer, Norbert, Wong, K., Norbert Maurer, Stark, Holger, Louie, Lenore, Lenore Louie, Wong, T., Maurer, N., Cullis, P. R., Wong, Tabitha, Tabitha Wong, Cullis, P., Kim F. Wong   +29 more
core   +1 more source

STUDIES ON POLYNUCLEOTIDES SYNTHESIZED BY POLYNUCLEOTIDE PHOSPHORYLASE

Journal of Biological Chemistry, 1957
Leon A. Heppel, Priscilla J. Ortiz, Severo Ochoa   +2 more
openaire   +2 more sources

The Origins of Life: What One Needs to Know

Zygon, 1997
Many solar systems in the universe may be expected to contain rocky planets that have accreted organic compounds. These compounds are likely to be universally found. In addition, the chemistry of sulfur, phosphorus, and iron is likely to dominate energy
doaj   +2 more sources