The human neurotropic virus JC Polyomavirus, a member of the Polyomaviridae family, is the opportunistic infectious agent causing progressive multifocal leukoencephalopathy, typically in immunocompromised individuals.
Vijay Harypursat +3 more
doaj +1 more source
Implementation and Validation of the Roche Light Cycler 480 96-Well Plate Platform as a Real-Time PCR Assay for the Quantitative Detection of Cytomegalovirus (CMV) in Clinical Specimens Using the Luminex MultiCode ASRs System. [PDF]
Allogenic stem-cell therapies benefit patients in the treatment of multiple diseases; however, the side effects of stem-cell therapies (SCT) derived from the concomitant use of immune suppression agents often include triggering infection diseases.
Li, Shengwen Calvin +2 more
core +1 more source
ICTV Virus Taxonomy Profile: Polyomaviridae
The Polyomaviridae is a family of small, non-enveloped viruses with circular dsDNA genomes of approximately 5 kbp. The family includes four genera whose members have restricted host range, infecting mammals and birds. Polyomavirus genomes have also been detected recently in fish.
Moens, U. +8 more
openaire +5 more sources
The ovarian cancer oncobiome. [PDF]
Humans and other mammals are colonized by microbial agents across the kingdom which can represent a unique microbiome pattern. Dysbiosis of the microbiome has been associated with pathology including cancer.
Alwine, J.C. +7 more
core +2 more sources
Review on the Relationship between Human Polyomaviruses-Associated Tumors and Host Immune System
The polyomaviruses are small DNA viruses that can establish latency in the human host. The name polyomavirus is derived from the Greek roots poly-, which means “many,” and -oma, which means “tumours.” These viruses were originally isolated in mouse (mPyV)
Serena Delbue +2 more
doaj +1 more source
Exploring the Enteric Virome of Cats with Acute Gastroenteritis
Viruses are a major cause of acute gastroenteritis (AGE) in cats, chiefly in younger animals. Enteric specimens collected from 29 cats with acute enteritis and 33 non-diarrhoeic cats were screened in PCRs and reverse transcription (RT) PCR for a large ...
Federica Di Profio +6 more
doaj +1 more source
Urinary virome perturbations in kidney transplantation [PDF]
The human microbiome is important for health and plays a role in essential metabolic functions and protection from certain pathogens. Conversely, dysbiosis of the microbiome is seen in the context of various diseases. Recent studies have highlighted that
Carrie D. Nicora +7 more
core +5 more sources
Insights into Polyomaviridae MicroRNA Function Derived from Study of the Bandicoot Papillomatosis Carcinomatosis Viruses [PDF]
ABSTRACT Several different members of the Polyomaviridae , including some human pathogens, encode microRNAs (miRNAs) that lie antisense with respect to the early gene products, the tumor (T) antigens. These miRNAs negatively regulate T antigen expression by directing small interfering RNA (siRNA)-like ...
Chen, Chun Jung +4 more
openaire +3 more sources
The rapidly expanding family of human polyomaviruses: recent developments in understanding their life cycle and role in human pathology. [PDF]
Since their discovery in 1971, the polyomaviruses JC (JCPyV) and BK (BKPyV), isolated from patients with progressive multifocal leukoencephalopathy and polyomavirus-associated nephropathy, respectively, remained for decades as the only known members of ...
Martyn K White +2 more
doaj +1 more source
Different behaviour of BK-virus infection in liver transplant recipients [PDF]
Polyomavirus BK (BKV) infects up to 90% of the general population. After primary infection, occurring early during childhood, a state of non-replicative infection is established in the reno-urinary tract, without complications for immunocompetent hosts ...
MITTERHOFER, Anna Paola +3 more
core +3 more sources

