Results 11 to 20 of about 6,754 (176)
Urothelial Carcinoma of the Bladder Following BK Virus Infection in a Pediatric Kidney Transplant Recipient. [PDF]
Pediatr TransplantABSTRACT Background Urothelial bladder carcinoma is extremely rare in children and its association with BK virus infection remains unclear. Methods We describe the case of an 11‐year‐old girl who developed a urothelial carcinoma of the bladder four years after receiving her first kidney transplant.
Ichas M +7 more
europepmc +2 more sources
BK Polyomavirus and Transformation [PDF]
American Journal of Transplantation, 2011 The human BK polyomavirus (PyV) (BKV) was isolated from the urine of a kidney transplant patient with the initials B.K. after cells with nuclear atypia were noted in the urine in the diagnostic workup of an alloureter stenosis. Electron microscopy revealed intranuclear inclusions of nonenveloped viral particles of 40–45-nm diameter suggesting infection
Tina Dalianis, Hans H. Hirsch
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Cytomegalovirus and polyomavirus BK posttransplant [PDF]
Nephrology Dialysis Transplantation, 2007 Virus replication and progression to disease in transplant patients is determined by patient-, graft- and virus-specific factors. This complex interaction is modulated by the net state of immunosuppression and its impact on virus-specific cellular immunity.
Adrian, Egli +8 more
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Role of BK human polyomavirus in cancer [PDF]
Infectious Agents and Cancer, 2018 Human polyomaviruses (HPyV), which are small DNA viruses classified into the polyomaviridae family, are widely distributed in human populations. Thirteen distinct HPyVs have been described to date. Some of these viruses have been found in human tumors, suggesting an etiological relationship with cancer.
Levican, Jorge +4 more
openaire +8 more sources
BK Polyomavirus in Solid Organ Transplantation [PDF]
American Journal of Transplantation, 2013 The human BK polyomavirus (BKV) is the major cause of polyomavirus-associated nephropathy (PyVAN) putting 1-15% of kidney transplant patients at risk of premature allograft failure, but is less common in other solid organ transplants. Because effective antiviral therapies are lacking, screening kidney transplant patients for BKV replication in urine ...
Hirsch, H. H., Randhawa, P.
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The Agnogene of the Human Polyomavirus BK Is Expressed [PDF]
Journal of Virology, 1998 ABSTRACT Primate polyomavirus genomes all contain an open reading frame at the 5′ end of the late coding region called the agnogene. A simian virus 40 agnoprotein with unknown functions has previously been demonstrated. We now show that a BK virus agnoprotein appears in the perinuclear area and cytoplasm late in the infectious cycle.
C H, Rinaldo, T, Traavik, A, Hey
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Optimized amplification of BK polyomavirus in urine
Journal of Virological Methods, 2022 BK polyomavirus (BKPyV) is a ubiquitous pathogen that typically results in asymptomatic infection. However, in immunocompromised individuals, BKPyV viral shedding in the urine can reach 109 copies per mL. These high viral levels within urine provide ideal samples for next-generation sequencing to accurately determine BKPyV genotype and identify ...
Elizabeth A. Odegard +9 more
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Journal of Medical Case Reports, 2017 Background BK polyomavirus-associated nephropathy is an important cause of post-transplantation renal failure. We present two cases of BK polyomavirus-associated nephropathy who were submitted to contrasting strategies of clinical follow-up to BK ...
Ana Luisa Figueira Gouvêa +10 more
doaj +1 more source
Phylogenetic Analysis of Polyomavirus BK Sequences [PDF]
Journal of Virology, 2006 ABSTRACT Polyomavirus BK (BKV) has emerged as an important pathogen in kidney transplant patients. Existing taxonomic classifications of BKV come from conventional DNA sequence alignments based on limited data derived from the VP1 gene. We have used a phylogenetic whole-genome approach to examine the pattern of diversity and evolutionary ...
Preety M, Sharma +4 more
openaire +3 more sources
The complete genome sequence BK polyomavirus study in kidney transplanted patients [PDF]
Journal of Nephropathology, 2019 Background: BK polyomavirus is a member of the Polyomaviridae. This virus has spread worldwide and up to 82% of the world populations are serologically positive. BK polyomavirus usually transmits through inhalation or fecal-oral way in childhood, as well
Manoochehr Makvandi +5 more
doaj +1 more source