Results 21 to 30 of about 12,049 (265)

Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy [PDF]

International Journal of Organ Transplantation Medicine, 2015
Background: Polyomavirus BK is a major cause of nephropathy in immunosuppressed transplanted patients. Non-invasive diagnostic protocols such as molecular detection of polyomavirus BK replication are a useful strategy to predict BK virus-associated ...
M Pakfetrat, R Yaghobi, Z Salmanpoor, J Roozbeh, S Torabinezhad, S Kadkhodaei   +5 more
doaj   +1 more source

Role of BK Virus CTLs in the Treatment of BK Virus-Associated Nephropathy in Kidney-Transplant and Hematopoietic Cell Transplant Recipients. [PDF]

Transpl Infect Dis
Third‐party, BK virus‐specific cytotoxic T lymphocytes (CTLs) were safe and effective in reducing viremia in kidney and stem cell transplant recipients with BK virus nephropathy. However, they did not improve kidney function. Earlier administration may be more beneficial before nephropathy and irreversible damage occur.
Olson A, Li YE, Basar R, Banerjee P, Kaur I, Abueg G, Sylejmani M, Uprety N, Shrestha R, Silva FR, Page V, Champlin RE, Kontoyiannis DP, Chemaly RF, Shpall EJ, Moore L, Gaber OA, Rezvani K, Abudayyeh A.   +18 more
europepmc   +2 more sources

Late BK Nephropathy 15 years post kidney transplant following chemotherapy: A case report [PDF]

IDCases
BK Polyomavirus (BKPyV) is an important risk factor for premature graft loss following kidney transplant. Current practice guidelines recommend screening for BK virus DNA for 2 years after kidney transplant as the risk of BK Polyomavirus associated ...
Anum Hamiduzzaman, Jean Hou, Tram Higgins, Pryce Gaynor, Abhirami Shankar, Erik L. Lum   +5 more
doaj   +2 more sources

BK Polyomavirus-Associated Nephropathy and Hemorrhagic Cystitis in Transplant Recipients—What We Understand and What Remains Unclear [PDF]

Viruses
The reactivation of BK polyomavirus (BKPyV) during severe immunosuppression plays a crucial role in two significant syndromes observed in transplant recipients: BK polyomavirus-associated nephropathy (BKPyVAN) in kidney transplant patients and BK ...
Tang-Her Jaing, Yi-Lun Wang, Tsung-Yen Chang   +2 more
doaj   +2 more sources

Surveillance of polyomavirus BK in relation to immunosuppressive therapy in kidney transplantation

Microbiologia Medica, 2012
Introduction. Reactivation of polyomavirus BK in kidney transplant recipients has been associated to the development of nephropathy (polyomavirus-associated nephropathy, PVAN), possibly leading to the loss of the transplanted organ.
Cristina Costa, Francesca Sidoti, Cinzia Balloco, Salvatore Simeone, Elsa Piasentin Alessio, Giovanni Antonio Touscoz, Maria Messina, Giuseppe Paolo Segoloni, Rossana Cavallo   +8 more
doaj   +3 more sources

BK Polyomavirus and Transformation [PDF]

American Journal of Transplantation, 2011
The human BK polyomavirus (PyV) (BKV) was isolated from the urine of a kidney transplant patient with the initials B.K. after cells with nuclear atypia were noted in the urine in the diagnostic workup of an alloureter stenosis. Electron microscopy revealed intranuclear inclusions of nonenveloped viral particles of 40–45-nm diameter suggesting infection
Tina Dalianis, Hans H. Hirsch
openaire   +5 more sources

Gut Microbiota Dysbiosis in BK Polyomavirus-Infected Renal Transplant Recipients: A Case-Control Study

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundBK polyomavirus infection results in renal allograft dysfunction, and it is important to find methods of prediction and treatment. As a regulator of host immunity, changes in the gut microbiota are associated with a variety of infections ...
Jian Zhang, Jian Zhang, Hao Qin, Mingyu Chang, Yang Yang, Jun Lin, Jun Lin   +6 more
doaj   +1 more source

Exploring the mechanism of BK polyomavirus-associated nephropathy through consensus gene network approach.

PLoS ONE, 2023
BK polyomavirus-associated nephropathy occurs in kidney transplant recipients under immunosuppressive treatment. BK polyomavirus is implicated in cancer development and invasion, and case reports of renal cell carcinoma and urothelial carcinoma possibly ...
Noriaki Sato, Keita P Mori, Kaoru Sakai, Hitomi Miyata, Shinya Yamamoto, Takashi Kobayashi, Hironori Haga, Motoko Yanagita, Yasushi Okuno   +8 more
doaj   +1 more source

Cytomegalovirus and polyomavirus BK posttransplant [PDF]

Nephrology Dialysis Transplantation, 2007
Virus replication and progression to disease in transplant patients is determined by patient-, graft- and virus-specific factors. This complex interaction is modulated by the net state of immunosuppression and its impact on virus-specific cellular immunity.
Adrian, Egli, Simone, Binggeli, Sohrab, Bodaghi, Alexis, Dumoulin, Georg A, Funk, Nina, Khanna, David, Leuenberger, Rainer, Gosert, Hans H, Hirsch   +8 more
openaire   +3 more sources

BK Polyomavirus in Solid Organ Transplantation [PDF]

American Journal of Transplantation, 2013
The human BK polyomavirus (BKV) is the major cause of polyomavirus-associated nephropathy (PyVAN) putting 1-15% of kidney transplant patients at risk of premature allograft failure, but is less common in other solid organ transplants. Because effective antiviral therapies are lacking, screening kidney transplant patients for BKV replication in urine ...
Hirsch, H. H., Randhawa, P.
openaire   +4 more sources