Phylogenetic Analysis of Polyomavirus BK Sequences [PDF]
ABSTRACT Polyomavirus BK (BKV) has emerged as an important pathogen in kidney transplant patients. Existing taxonomic classifications of BKV come from conventional DNA sequence alignments based on limited data derived from the VP1 gene. We have used a phylogenetic whole-genome approach to examine the pattern of diversity and evolutionary ...
Preety M, Sharma +4 more
openaire +3 more sources
Polyomavirus BK with rearranged noncoding control region emerge in vivo in renal transplant patients and increase viral replication and cytopathology [PDF]
Immunosuppression is required for BK viremia and polyomavirus BK-associated nephropathy (PVAN) in kidney transplants (KTs), but the role of viral determinants is unclear.
Hirsch, Hans H. +13 more
core +1 more source
The complete genome sequence BK polyomavirus study in kidney transplanted patients [PDF]
Background: BK polyomavirus is a member of the Polyomaviridae. This virus has spread worldwide and up to 82% of the world populations are serologically positive. BK polyomavirus usually transmits through inhalation or fecal-oral way in childhood, as well
Manoochehr Makvandi +5 more
doaj +1 more source
Characterizing determinants of BK Polyomavirus-specific immune response [PDF]
BK polyomavirus (BKPyV) is one of now 13 human polyomavirus (HPyV) species detected in humans. BKPyV is only known to infect humans and seroprevalence rates of more than 90% have been reported in adult populations around the world.
Cioni, Michela
core +1 more source
Adaptive immune response against BK polyomavirus infection [PDF]
BK polyomavirus is a small non-enveloped virus that is found in a large proportion of the human population. BKPyV infection commonly occurs in early childhood. The virus establishes persistent infection in renal tubular cells and uroepithelial cells.
Rezlerová, Adéla
core +1 more source
Prevalence of cytomegalovirus and BK polyoma virus infection in post-renal transplant patients in a tertiary care centre in South India [PDF]
Background: Viral infections are a significant cause of graft loss and dysfunction in kidney transplant recipients. Cytomegalovirus and BK polyomavirus have often been explained as the most common viral etiological agents.
Kevin Manuel +4 more
doaj +1 more source
JC and BK polyomavirus-like particles as targets of innate and adaptive humoral immunity [PDF]
JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV) were identified as the first of now more than 12 human polyomaviruses (HPyVs). The average JCPyV and BKPyV seroprevalence rates in adults are 70% and 90%, respectively. After asymptomatic infection both
Kardas, Piotr
core +1 more source
In vitro and in vivo characterization of the cytomegalovirus and polyomavirus BK specific immune response [PDF]
During my PhD thesis several aspects of the interaction of Cytomegalovirus and Polyomavirus BK with the host’s immune system were examined (see list of publications).
Egli, Adrian
core +1 more source
Polyomavirus BK-specific cellular immune response in Kidney transplant recipients [PDF]
Polyomavirus BK is an emerging pathogen in KT recipients. New potent immunosuppressive drugs promote reactivation and replication of BKV and progression towards PVAN.
Binggeli, Simone Young
core +1 more source
BKV Agnoprotein Interacts with α-Soluble N-Ethylmaleimide-Sensitive Fusion Attachment Protein, and Negatively Influences Transport of VSVG-EGFP [PDF]
Background: The human polyomavirus BK (BKV) infects humans worldwide and establishes a persistent infection in the kidney. The BK virus genome encodes three regulatory proteins, large and small tumor-antigen and the agnoprotein, as well as the capsid ...
Johannessen, M. +23 more
core +1 more source

