Results 101 to 110 of about 114,322 (384)

Polypharmacy and the occurrence of potential drug–drug interactions among geriatric patients at the outpatient pharmacy department of a regional hospital in Durban, South Africa

Journal of Pharmaceutical Policy and Practice, 2022
Background Polypharmacy is the administration of an excessive number of medicines and a significant irrational medicine use practice. Little is known about this practice in South Africa.
Adetola Olaniyi Bojuwoye, F. Suleman, V. Perumal-Pillay   +2 more
semanticscholar   +1 more source

Trends in drug–drug interaction prevalence and longitudinal associations with health outcomes in the older community‐dwelling population: Findings from The Irish LongituDinal study on Ageing

British Journal of Clinical Pharmacology, EarlyView.
Aims We estimate trends in severe drug–drug interaction (DDI) prevalence and examine longitudinal associations between DDI exposure and health outcomes (emergency department [ED] visits, quality‐of‐life [QoL] and functional decline) over approximately 10‐years in the older community‐dwelling population in Ireland.
John E. Hughes, Caitriona Cahir, Kathleen E. Bennett   +2 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Escalating polypharmacy [PDF]

QJM, 2006
New drug treatments, new indications for older drug treatments, lower thresholds for treating risk factors in preventative medicine, and an ageing population acquiring multiple pathologies all contribute to the development of polypharmacy. Longitudinal studies document the rise in prescribed medications, particularly in the elderly.
openaire   +2 more sources

Prevalence of polypharmacy in community-dwelling older adults from seven centres in five European countries: a cross-sectional study of DO-HEALTH

BMJ Open, 2022
Objective To investigate the prevalence of polypharmacy and characteristics associated with polypharmacy in older adults from seven European cities. Design Cross-sectional study of baseline data from DO-HEALTH. Setting and participants DO-HEALTH enrolled
C. de Godoi Rezende Costa Molino, P. Chocano-Bedoya, A. Sadlon, R. Theiler, J. Orav, B. Vellas, R. Rizzoli, R. Kressig, J. Kanis, S. Guyonnet, W. Lang, A. Egli, H. Bischoff-Ferrari   +12 more
semanticscholar   +1 more source

Trends in opioid prescribing in Scandinavian countries from 2010 to 2023: Insights from multi‐metric evaluation

British Journal of Clinical Pharmacology, EarlyView.
Aims Monitoring opioid prescribing across different healthcare systems is essential to understanding population‐level exposure and informing global health policies. This study examined opioid utilization in Scandinavian countries between 2010 and 2023 using multiple complementary metrics, addressing the limitations of single‐metric comparisons ...
Gabriela Rolová, Svetlana Skurtveit, Marte Handal, Geana Paula Kurita, Torgeir Gilje Lid, Ingvild Odsbu, Mikael Hoffmann   +6 more
wiley   +1 more source

Prevalence of polypharmacy and associated adverse health outcomes in adult patients with chronic kidney disease: protocol for a systematic review and meta-analysis

Systematic Reviews, 2021
Background Polypharmacy, often defined as the concomitant use of ≥ 5 medications, has been identified as a significant global public health threat. Aging and multimorbidity are key drivers of polypharmacy and have been linked to a broad range of adverse ...
Ikechi G. Okpechi, Mohammed M. Tinwala, Shezel Muneer, Deenaz Zaidi, Feng Ye, Laura N. Hamonic, Maryam Khan, Naima Sultana, Scott Brimble, Allan Grill, Scott Klarenbach, Cliff Lindeman, Amber Molnar, Dorothea Nitsch, Paul Ronksley, Soroush Shojai, Boglarka Soos, Navdeep Tangri, Stephanie Thompson, Delphine Tuot, Neil Drummond, Dee Mangin, Aminu K. Bello   +22 more
doaj   +1 more source

Health-related preferences of older patients with multimorbidity: the protocol for an evidence map [PDF]

, 2019
Introduction: Interaction of conditions and treatments, complicated care needs and substantial treatment burden make patient–physician encounters involving multimorbid older patients highly complex.
Blom, Jeanet, Gerlach, Ferdinand M, González-González, Ana Isabel, Hoffmann, Tammy, Meerpohl, Joerg J, Muth, Christiane, Nguyen, Truc Sophia, Nothacker, Julia, Röttger, Kristian, Schmucker, Christine, Straus, Sharon E, van den Akker, Marjan, Wegwarth, Odette   +12 more
core   +1 more source

Deprescribing drugs with anticholinergic effects in older patients with increased risk of dementia in the multicomponent intervention study AgeWell.de

British Journal of Clinical Pharmacology, EarlyView.
Aim Drugs with anticholinergic effects are often considered as potentially inappropriate medications, especially for older patients, and deprescribing such drugs may improve cognitive function. The aim was to investigate the effectiveness of counselling on drug risks as part of a multimodal intervention to prevent cognitive decline. Methods The AgeWell.
Laura K. Lepenies, Hanna M. Seidling, Alexander Pabst, Melanie Luppa, Juliane Döhring, Martin Williamson, Thomas Frese, Jochen Gensichen, Wolfgang Hoffmann, Hanna Kaduszkiewicz, Hans‐Helmut König, Jochen René Thyrian, Birgitt Wiese, Steffi G. Riedel‐Heller, David Czock   +14 more
wiley   +1 more source

The Prevalence of Polypharmacy and Potentially Inappropriate Medications and Its Relationship with Cognitive Status in Portuguese Institutionalized Older Adults: A Cross-Sectional Study

International Journal of Environmental Research and Public Health, 2022
The aim of this study was to evaluate the prevalence of polypharmacy and potentially inappropriate medications (PIMs) in a population of older adults living in nursing homes.
C. Caçador, Edite Teixeira-Lemos, Jorge Oliveira, J. Pinheiro, Luís Teixeira-Lemos, F. Ramos   +5 more
semanticscholar   +1 more source