Results 31 to 40 of about 114,322 (384)

Modeling polypharmacy side effects with graph convolutional networks [PDF]

open access: yesbioRxiv, 2018
Motivation: The use of drug combinations, termed polypharmacy, is common to treat patients with complex diseases or co-existing conditions. However, a major consequence of polypharmacy is a much higher risk of adverse side effects for the patient ...
M. Zitnik, Monica Agrawal, J. Leskovec
semanticscholar   +1 more source

Risk of Polypharmacy and Its Outcome in Terms of Drug Interaction in an Elderly Population: A Retrospective Cross-Sectional Study

open access: yesJournal of Clinical Medicine, 2023
The simultaneous use of multiple drugs—termed ‘polypharmacy’—is often required to manage multiple physiological and biological changes and the interplay between chronic disorders that are expected to increase in association with ageing.
Reham M. Alhumaidi   +7 more
semanticscholar   +1 more source

Are there socioeconomic inequalities in polypharmacy among older people? A systematic review and meta-analysis

open access: yesBMC Geriatrics, 2023
Background Socioeconomic status (SES) may influence prescribing, concordance and adherence to medication regimens. This review set out to investigate the association between polypharmacy and an individual’s socioeconomic status.
A. Iqbal   +6 more
semanticscholar   +1 more source

Adverse drug reactions, multimorbidity and polypharmacy: a prospective analysis of 1 month of medical admissions

open access: yesBMJ Open, 2022
Objective To ascertain the burden and associated cost of adverse drug reactions (ADRs), polypharmacy and multimorbidity through a prospective analysis of all medical admissions to a large university teaching hospital over a 1-month period.
R. Osanlou   +4 more
semanticscholar   +1 more source

Prevalence and impact of polypharmacy in older patients with type 2 diabetes

open access: yesAging Clinical and Experimental Research, 2022
Polypharmacy is a prevalent condition in older adults, especially those with multiple chronic diseases, and has been largely associated with adverse outcomes, including disability, hospitalizations, and death.
Francesca Remelli   +4 more
semanticscholar   +1 more source

Polypharmacy and potentially inappropriate medication use in geriatric oncology. [PDF]

open access: yes, 2016
Polypharmacy is a highly prevalent problem in older persons, and is challenging to assess and improve due to variations in definitions of the problem and the heterogeneous methods of medication review and reduction.
Aparicio   +65 more
core   +2 more sources

El reto del envejecimiento y la complejidad farmacoterapéutica en el paciente VIH+ [PDF]

open access: yes, 2018
Objective: To describe the current knowledge and management of aging and pharmacotherapeutic complexity in HIV + patients. Method: A review of literature was carried out, including articles, originals or reviews, published in English or Spanish, from ...
Abdel Kader Martín, Laila   +3 more
core   +3 more sources

Evaluation of a pharmacist-led medication assessment used to identify prevalence of and associations with polypharmacy and potentially inappropriate medication use among ambulatory senior adults with cancer. [PDF]

open access: yes, 2015
PURPOSE: The use of multiple and/or inappropriate medications in seniors is a significant public health problem, and cancer treatment escalates its prevalence and complexity.
Andrel-Sendecki, Jocelyn   +4 more
core   +2 more sources

Coping with complexity: working beyond the guidelines for patients with multimorbidities [PDF]

open access: yes, 2015
Primary care physicians believe they are delivering evidence-based care, understanding that adherence to evidence-based clinical guidelines results in tangible benefits in the populations for which they were developed.
Treadwell, Julian
core   +6 more sources

Factors related to polypharmacy and hyper‐polypharmacy for the elderly: A nationwide cohort study using National Health Insurance data in South Korea

open access: yesClinical and Translational Science, 2023
Polypharmacy may cause adverse health outcomes in the elderly. This study examined the prevalence of continuous polypharmacy and hyper‐polypharmacy, factors associated with polypharmacy, and the most frequently prescribed medications among older adults ...
Ho Jin Cho   +3 more
doaj   +1 more source

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