Results 61 to 70 of about 1,013 (157)

Optimization of a high throughput screening platform to identify inhibitors of asymmetric diadenosine polyphosphatases

Analytical Biochemistry
When stressed, cells synthesize di-adenosine polyphosphates (ApnA), and cellular organisms also express proteins that degrade these compounds to release ATP. Most of these proteins are members of the nudix hydrolase superfamily, and several are involved in bacterial pathogenesis, neurodevelopment, and cancer.
David N. Frick, Mujidat Shittu, Chase R. Bock, Zoe P. Wardle, Abdullah A. Rauf, Julian N. Ramos, Joshua G. Thomson, Daniel J. Sheibley, Suzanne F. O'Handley   +8 more
openaire   +2 more sources

Recent developments in the biochemistry and ecology of enhanced biological phosphorus removal

, 2000
Most of the genes encoding the enzymes involved in polyP synthesis and degradation and in phosphate transport have been studied in various Gram-negative bacteria.
Bonting, C.F.C., Appeldoorn, K.J., Kortstee, G.J.J., Niel, E.W.J., van, Veen, H.W., van   +4 more
core   +2 more sources

New Strategies for the Isolation of Microorganisms Responsible for Phosphate Accumulation

, 1985
Several strategies were used to isolate organisms involved in the uptake and subsequent release of inorganic phosphate from waste water sludge. These included direct staining for polyphosphates (polyP), growing in 32P inorganic phosphate followed by ...
M. Coccia, J. Wells, N. Suresh, M. F. Roberts, M. Timmerman, R. Warburg, H. O. Halvorson   +6 more
core   +1 more source

Association study of the INPP1, 5HTT, BDNF, AP-2β and GSK-3β GENE variants and restrospectively scored response to lithium prophylaxis in bipolar disorder

, 2006
In the present study we investigated the influence of a series variants in genes (the serotonin transporter, glycogen synthase kinase-3 beta, inositol polyphosphatase 1-phosphate, brain-derived neurotrophic factor and activator protein 2 beta) related to
Meira-Lima, I, Cordeiro, Q, Miguita, K., Cordeiro, Q., Michelon, L., Collier, D, Michelon, L, Breen, G.; id_orcid, Vallada, H,, Breen, G, Collier, D., Meira-Lima, I., Miguita, K, Vallada, H.   +13 more
core   +1 more source

Accumulation and degradation of polyphosphate in Acinetobacter sp. [PDF]

, 1988
Biological phosphate removal from waste water is a biotechnological alternative to chemical phosphorus precipitation. This process is obtained by recycling the sludge through anaerobic and aerobic zones.
Groenestijn, J.W., van
core  

Membrane-bound and soluble polyphosphatases of mitochondria of Saccharomyces cerevisiae: identification and comparative characterization

, 2002
Isolated mitochondria of Saccharomyces cerevisiae possess polyphosphatases insensitive to a number of inhibitors of ATPase and pyrophosphatase of the same organelles and differing from the last two by neutral pH optima and molecular masses.
Igor Kulaev, Lidia Lichko, Tatyana Kulakovskaya   +2 more
core   +1 more source

Polyphosphate: a fundamental regulator of protein folding in human osteoblasts

, 2018
Polyphosphate (polyP) is structurally simple as a linear chain of phosphate residues linked by ATPlike bonds. Yet, polyP critically affects a range of fundamental biological processes with vague understanding of its mechanistic action in higher ...
Khong, ML, Pavlov, E, Li, L, Solesio, MET, Tanner, JA   +4 more
core  

De novo synthesis and functional analysis of the phosphatase-encoding gene acI-B of uncultured Actinobacteria from Lake Stechlin (NE Germany) [PDF]

, 2016
The National Center for Biotechnology Information [http://www.ncbi.nlm.nih.gov/guide/taxonomy/] database enlists more than 15,500 bacterial species. But this also includes a plethora of uncultured bacterial representations.
Grossart, Hans-Peter, D McMahon, Katherine, Srivastava, Abhishek, Stepanauskas, Ramunas   +3 more
core  

Arabidopsis thaliana NudiXes have RNA-decapping activity. [PDF]

RSC Chem Biol, 2023
Mititelu MB, Hudeček O, Gozdek A, Benoni R, Nešuta O, Krasnodębski S, Kufel J, Cahová H.   +7 more
europepmc   +1 more source

Inorganic Polyphosphate in Hematolymphoid Malignancies: Biological Rationale and Emerging Research Gaps. [PDF]

Biomolecules
García-Domínguez F, Fernandez-Ponce C, Salb-Pernas C, Santisteban-Espejo A, Ruiz FA.   +4 more
europepmc   +1 more source