Results 41 to 50 of about 994 (158)

Pathogenicity of Salmonella: SopE-mediated membrane ruffling is independent of inositol phosphate signals [PDF]

, 2006
Studies [Zhou, D. Chen, L.-M. Hernandez, L. Shears, S.B. and Galán, J.E. (2001) A Salmonella inositol polyphosphatase acts in conjunction with other bacterial effectors to promote host-cell actin cytoskeleton rearrangements and bacterial internalization.
Deleu, Sandrine, Shears, Stephen B., Reece, Jeff M., Shears, Stephen B, Choi, Kuicheon   +4 more
core   +1 more source

Platelets and Their Role in Immunity: Formation, Activation and Activity, and Biologically Active Substances in Their Granules and Extracellular Vesicles

International Journal of Inflammation, Volume 2025, Issue 1, 2025.
When presenting the role of platelets in immunity, the organelles and processes occurring within them are listed, and due to their lack of a cell nucleus, their specific transcriptional activity is discussed. Their formation, activation, and functional activity are also described, along with the characterization of elements important for shaping their ...
Beata Tokarz-Deptuła, Łukasz Baraniecki, Joanna Palma, Michał Stosik, Anhelli Syrenicz, Roman Kołacz, Wiesław Deptuła, Mariusz Sikora   +7 more
wiley   +1 more source

Advances in the Understanding of the Pathogenesis of Triple‐Negative Breast Cancer

Cancer Medicine, Volume 13, Issue 22, November 2024.
ABSTRACT Background Triple‐negative breast cancer (TNBC) is a heterogeneous disease characterized by high aggressiveness, high malignancy, and poor prognosis compared to other breast cancer subtypes. Objective This review aims to explore recent advances in understanding TNBC and to provide new insights and potential references for clinical treatment ...
Yuhan Liu, Yuhan Zou, Yangli Ye, Yong Chen   +3 more
wiley   +1 more source

Inorganic polyphosphate controls cyclophilin B‐mediated collagen folding in osteoblast‐like cells

, 2020
Evidence is emerging that inorganic polyphosphate (polyP) is a fundamental molecule involved in a wide range of biological processes. In higher eukaryotes, polyP is abundant in osteoblasts but questions remain as to its functions.
Julian A. Tanner, Li, L, Evgeny V. Pavlov, Pavlov, EV, KHONG, ML, Mei Li Khong, Lina Li, Solesio, ME, Maria E. Solesio, Tanner, JA   +9 more
core   +1 more source

Rapid Fluorescence Assay for Polyphosphate in Yeast Extracts Using JC‐D7

Yeast, Volume 41, Issue 10, Page 593-604, October 2024.
Evaluation and application of the fluorescent dye JC‐D7 for polyphosphate detection in yeast extracts. ABSTRACT Polyphosphate (polyP) is an intriguing molecule that is found in almost any organism, covering a multitude of cellular functions. In industry, polyP is used due to its unique physiochemical properties, including pH buffering, water binding ...
Alexander Deitert, Jana Fees, Anna Mertens, Duc Nguyen Van, Maria Maares, Hajo Haase, Lars Mathias Blank, Claudia Keil   +7 more
wiley   +1 more source

Composition of ES in L. sigmodontis adult worms compared to ES products of all lifecycle stages.

, 2019
(A) Composition of the sRNA sequencing libraries made in the absence (-) or presence (+) of polyphosphatase (polyP) from male (AM) and gravid adult female (gAF) worms in comparison to the ES of gAFs.
Matthew Taylor (39753), Simon A. Babayan (8044505), Alison Fulton (8044502), Paul Dickinson (185518), Coralie Martin (171733), Juan F. Quintana (8044493), Franklin W. N. Chow (8044496), Sujai Kumar (3250173), Anna M. Hoy (8044499), Amy H. Buck (525371), Alasdair Ivens (33327)   +10 more
core   +1 more source

Inpp5d haplodeficiency alleviates tau pathology in the PS19 mouse model of Tauopathy

Alzheimer's &Dementia, Volume 20, Issue 7, Page 4985-4998, July 2024.
Abstract INTRODUCTION A noncoding variant (rs35349669) within INPP5D, a lipid and protein phosphatase restricted to microglia in the brain, is linked to increased susceptibility to Alzheimer's disease (AD). While Inpp5d is well‐studied in amyloid pathology, its role in tau pathology remains unclear.
Disha M. Soni, Peter Bor‐Chian Lin, Audrey Lee‐Gosselin, Christopher D. Lloyd, Emily Mason, Cynthia M. Ingraham, Abigail Perkins, Miguel Moutinho, Bruce T. Lamb, Shaoyou Chu, Adrian L. Oblak   +10 more
wiley   +1 more source

An improved method of sncRNA cDNA library construction

四川大学学报. 自然科学版, 2017
With the increasing recognization of sncRNA, especially miRNA and piRNA, it has been proved that small noncoding RNA (sncRNA，
DU Guang-Shi, LUO Fa-Tao, XIAO Yan, CHEN Hong-Jun, WU Chuan-Fang   +4 more
doaj  

Protein purification via consecutive histidine–polyphosphate interaction

Protein Science, Volume 33, Issue 6, June 2024.
Abstract While nickel‐nitrilotriacetic acid (Ni‐NTA) has greatly advanced recombinant protein purification, its limitations, including nonspecific binding and partial purification for certain proteins, highlight the necessity for additional purification such as size exclusion and ion exchange chromatography.
Zihao Zhou, Jin Jin, Xu Deng, Zongchao Jia   +3 more
wiley   +1 more source

InflammamiRs in focus: Delivery strategies and therapeutic approaches

The FASEB Journal, Volume 38, Issue 5, 15 March 2024.
microRNAs (miRNAs) are non‐coding RNAs which regulate gene expression at the post‐transcriptional level. Dysregulated expression of miRNAs has been linked to the pathogenesis of inflammatory diseases. miRNAs that play a role in inflammatory pathways have been termed inflammamiRs.
Yeliz Z. Akkaya‐Ulum, Basak Sen, Tayfun Hilmi Akbaba, Banu Balci‐Peynircioglu   +3 more
wiley   +1 more source