Results 31 to 40 of about 994 (158)
, 2014 Enhanced biological phosphorus removal (EBPR) from wastewater relies on the preferential selection of active polyphosphate-accumulating organisms (PAO) in the underlying bacterial community continuum.
Chabrelie, Alexandre +5 more
core +2 more sources
ApaH Diadenosine Polyphosphatase from Legionella pneumophila
The FASEB Journal, 2011 Legionella pneumophila (LP), the causative agent of Legionnaires' disease, is a Gram‐negative bacterium and facultative intracellular parasite. The Nudix diadenosine polyphosphatase, NudA, is a virulence factor in LP, and a related nonNudix diadenosine polyphosphatase, ApaH, is a virulence factor in E. coli and acts additively with the E. coli NudA for
Alejandra Rizo Patron +6 more
openaire +1 more source
Circular Photocaged mRNA for Light‐induced Late‐stage Activation of Translation
Angewandte Chemie International Edition, EarlyView.A clickable photo‐caged 5′ cap (CyCliCap) allows to make Cyclic Click Cap‐containing mRNA (CyCliCap‐mRNA) which is remarkably stable and translationally muted until irradiated, allowing for late‐stage activation of translation in cells by light. ABSTRACT mRNA is a new medical modality as vaccine and raises hopes to become a protein replacement agent ...
Bayram Terzi +6 more
wiley +1 more source
ChemistryEurope, Volume 3, Issue 6, November 11, 2025.Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are useful tools to probe the functions of naturally occurring dinucleoside tetraphosphates and their role in bacteria and mammalian cells.
Cedrik Kühling +5 more
wiley +1 more source
, 2013 A) Confocal fluorescence microscopy of fixed HeLa cells transfected with a vector with: the NoLS-scPPX construct (pIRES-NoLS-scPPX), a scPPX construct (pIRES-scPPX), or an empty vector (pIRES).
Concepción Iglesias (388834) +6 more
core +1 more source
A nucleotide metabolite controls stress-responsive gene expression and plant development.
PLoS ONE, 2011 Abiotic stress, such as drought and high salinity, activates a network of signaling cascades that lead to the expression of many stress-responsive genes in plants. The Arabidopsis FIERY1 (FRY1) protein is a negative regulator of stress and abscisic acid (
Hao Chen +3 more
doaj +1 more source
Environmental Microbiology, Volume 27, Issue 7, July 2025.Genomic analysis, diel gene expression profiling, and physiological monitoring were combined to uncover how the unicellular cyanobacteria Crocosphaera thrive in low‐phosphate environments. Our results indicate that the strategic use of dissolved organic phosphorus (DOP) is central to its adaptation, providing new insights into microbial resilience in ...
Chloé Caille +9 more
wiley +1 more source
Diadenosine Tetraphosphate (Ap4A) Serves as a 5′ RNA Cap in Mammalian Cells
Angewandte Chemie, Volume 136, Issue 6, February 5, 2024.Diadenosine tetraphosphate‐RNA (Ap4A‐RNA) is found in human and rat cell lines. Its amount is not dependent on the intracellular concentration of Ap4A. Ap4A‐RNA is decapped by two enzymes, NUDT2 and DXO. Even though Ap4A‐RNA is present in the same fraction as mRNA, it is not translated. However, it is recognized as self RNA by the innate immune system,
Jiří František Potužník +11 more
wiley +2 more sources
, 1991 The extracellular presence of adenosine polyphosphatase was investigated in a number of rat tissues. The enzyme was demonstrated in basement membranes of epithelial cells of duodenum, urinary bladder, tongue, choroid plexus, submandibular salivary gland,
BAKKER, WW +4 more
core +1 more source
The Mysterious World of Non‐Canonical Caps – What We Know and Why We Need New Sequencing Techniques
ChemBioChem, Volume 26, Issue 3, February 1, 2025.This review describes sophisticated methodologies such as LC–MS that enabled the identification of 5’ non‐canonical RNA caps and also surveys so far developed sequencing methods, evaluating their advantages and disadvantages. It emphasizes the need for developing new, reliable sequencing techniques to identify RNA types with non‐canonical caps enabling
Flaminia Mancini, Hana Cahova
wiley +1 more source