Results 31 to 40 of about 1,013 (157)

Zirkuläre, Photogeschützte mRNA für Lichtinduzierte Aktivierung der Translation zu späten Zeitpunkten

open access: yesAngewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Eine klickbare, photogeschützte 5′‐Kappe (CyCliCap) zur Herstellung von zyklischer, Click‐Cap enthaltender mRNA (Cyclic Click Cap‐mRNA), die bis zur Bestrahlung beachtlich stabil und translational stumm ist, ermöglicht die Aktivierung der Translation in Zellen zu späten Zeitpunkten mittels Lichts. ZUSAMMENFASSUNG mRNA ist eine neue Impfstofftechnologie
Bayram Terzi   +6 more
wiley   +1 more source

Photocaged Dinucleoside Tetraphosphates for Light‐Mediated Activation of 5′ Cap Interactions and Translation In Vitro

open access: yesChemistryEurope, Volume 3, Issue 6, November 11, 2025.
Photocaged dinucleoside tetraphosphates can be incorporated into mRNA by T7 RNA polymerase. Subsequent irradiation with light activates 5′ cap interactions and translation. These 5′ cap analogs are useful tools to probe the functions of naturally occurring dinucleoside tetraphosphates and their role in bacteria and mammalian cells.
Cedrik Kühling   +5 more
wiley   +1 more source

Inorganic polyphosphate controls cyclophilin B‐mediated collagen folding in osteoblast‐like cells

open access: yes, 2020
Evidence is emerging that inorganic polyphosphate (polyP) is a fundamental molecule involved in a wide range of biological processes. In higher eukaryotes, polyP is abundant in osteoblasts but questions remain as to its functions.
Julian A. Tanner   +9 more
core   +1 more source

Unveiling Crocosphaera Responses to Phosphorus Depletion: Insights From Genome Analysis and Functional Characterization

open access: yesEnvironmental Microbiology, Volume 27, Issue 7, July 2025.
Genomic analysis, diel gene expression profiling, and physiological monitoring were combined to uncover how the unicellular cyanobacteria Crocosphaera thrive in low‐phosphate environments. Our results indicate that the strategic use of dissolved organic phosphorus (DOP) is central to its adaptation, providing new insights into microbial resilience in ...
Chloé Caille   +9 more
wiley   +1 more source

Composition of ES in L. sigmodontis adult worms compared to ES products of all lifecycle stages.

open access: yes, 2019
(A) Composition of the sRNA sequencing libraries made in the absence (-) or presence (+) of polyphosphatase (polyP) from male (AM) and gravid adult female (gAF) worms in comparison to the ES of gAFs.
Matthew Taylor (39753)   +10 more
core   +1 more source

Diadenosine Tetraphosphate (Ap4A) Serves as a 5′ RNA Cap in Mammalian Cells

open access: yesAngewandte Chemie, Volume 136, Issue 6, February 5, 2024.
Diadenosine tetraphosphate‐RNA (Ap4A‐RNA) is found in human and rat cell lines. Its amount is not dependent on the intracellular concentration of Ap4A. Ap4A‐RNA is decapped by two enzymes, NUDT2 and DXO. Even though Ap4A‐RNA is present in the same fraction as mRNA, it is not translated. However, it is recognized as self RNA by the innate immune system,
Jiří František Potužník   +11 more
wiley   +2 more sources

Agrobacterium-mediated Soybean Transformation [PDF]

open access: yes, 2015
Soybean is a major crop in The United States. Frost and drought conditions pose serious hazards to the yield and quality of all crops. It is desirable to increase tolerance to drought and cold.
Ballard, Cale
core   +1 more source

ApaH diadenosine polyphosphatase from Legionella pneumophila

open access: yesThe FASEB Journal, 2013
The Nudix diadenosine polyphosphatase, NudA, is a virulence factor in Legionella pneumophila (LP), the causative agent of Legionnaires’ disease. The nonNudix diadenosine polyphosphatase, ApaH, is a virulence factor in E.
Michael Paul Madaio   +7 more
openaire   +1 more source

HISTOCHEMICAL DEMONSTRATION OF ACID TRIMETAPHOSPHATASE AND TETRAMETAPHOSPHATASE

open access: yes, 1960
Trimetaphosphatase is an acid inorganic polyphosphatase whose distribution and properties differ from those of acid and alkaline organic phosphatases. It is the enzyme responsible for previously reported "acid" polyphosphatase" staining.
GEORGE G. BERG
core   +1 more source

SURVEY OF THE OCCURRENCE OF ADENOSINE POLYPHOSPHATASE IN EXTRACELLULAR-MATRIX OF RAT-TISSUES - A CYTOCHEMICAL INVESTIGATION

open access: yes, 1991
The extracellular presence of adenosine polyphosphatase was investigated in a number of rat tissues. The enzyme was demonstrated in basement membranes of epithelial cells of duodenum, urinary bladder, tongue, choroid plexus, submandibular salivary gland,
BAKKER, WW   +4 more
core   +1 more source

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