Results 21 to 30 of about 994 (158)
The ApaH-like phosphatase TbALPH1 is the major mRNA decapping enzyme of trypanosomes. [PDF]
PLoS Pathogens, 2017 5'-3' decay is the major mRNA decay pathway in many eukaryotes, including trypanosomes. After deadenylation, mRNAs are decapped by the nudix hydrolase DCP2 of the decapping complex and finally degraded by the 5'-3' exoribonuclease. Uniquely, trypanosomes
Susanne Kramer
doaj +1 more source
Polyphosphatase Activity of CthTTM, a Bacterial Triphosphate Tunnel Metalloenzyme [PDF]
Journal of Biological Chemistry, 2008 Triphosphate tunnel metalloenzymes (TTMs) are a superfamily of phosphotransferases with a distinctive active site located within an eight-stranded beta barrel. The best understood family members are the eukaryal RNA triphosphatases, which catalyze the initial step in mRNA capping.
Ruchi, Jain, Stewart, Shuman
openaire +2 more sources
Traffic, Volume 24, Issue 6, Page 234-250, June 2023., 2023 Endosomal cargo sorting is an essential process in eukaryotic cells. Here, we review the recently characterized role of the Endosomal SNX‐BAR Sorting Complex for Promoting Exit‐1 (ESCPE‐1) in mediating sequence‐dependent endosomal cargo sorting, its subversion by intracellular pathogens during the infection process, and its restrictive role against a ...
Boris Simonetti +2 more
wiley +1 more source
Adaptive Responses of Cyanobacteria to Phosphate Limitation: A Focus on Marine Diazotrophs. [PDF]
Environ MicrobiolMarine diazotrophic cyanobacteria, which are essential for atmospheric nitrogen fixation in low‐nutrient oceans, have developed various strategies to survive under phosphate (Pi) limitation by using high‐affinity transporters and enzymes that break down dissolved organic phosphorus (DOP).
Caille C +3 more
europepmc +2 more sources
Angewandte Chemie, Volume 137, Issue 11, March 10, 2025.The more the merrier: Oligophosphorimidazolide reagents enable the concomitant conjugation of multiple phosphate units to phosphopeptides, yielding derivatives with monodisperse phosphate chain lengths (up to hexaphosphate). This simple transformation occurs chemoselectively under mild conditions.
Kevin Qian +3 more
wiley +2 more sources
Membrane-bound and soluble polyphosphatases of mitochondria of Saccharomyces cerevisiae: identification and comparative characterization [PDF]
, 1998 Isolated mitochondria of Saccharomyces cerevisiae possess polyphosphatases insensitive to a number of inhibitors of ATPase and pyrophosphatase of the same organelles and differing from the last two by neutral pH optima and molecular masses.
Lichko, Lidia +2 more
core +1 more source
Deciphering interplay between Salmonella invasion effectors. [PDF]
, 2008 Bacterial pathogens have evolved a specialized type III secretion system (T3SS) to translocate virulence effector proteins directly into eukaryotic target cells.
Robert J Cain +15 more
core +2 more sources
Substrate Binding in Protein-tyrosine Phosphatase-like Inositol Polyphosphatases [PDF]
Journal of Biological Chemistry, 2012 Protein-tyrosine phosphatase-like inositol polyphosphatases are microbial enzymes that catalyze the stepwise removal of one or more phosphates from highly phosphorylated myo-inositols via a relatively ordered pathway. To understand the substrate specificity and kinetic mechanism of these enzymes we have determined high resolution, single crystal, x-ray
Robert J, Gruninger +6 more
openaire +2 more sources
, 2022 Inclusion bodies are typically ignored as they are considered unwanted protein waste generated by prokaryotic host cells during recombinant protein production or harmful protein inclusions in human cell biology.
Jozef Nahalka (5711945) +3 more
core +1 more source
, 2013 The rh-TRAP was separated from Sf9 cell culture supernatant by co-precipitation with anti-TRAP antibodies (15A4 and 13B9). Polyphosphatase activity was also measured using [32P]poly(P)40 (0.346 mM) as substrate.
Kazuya Doi (299343) +7 more
core +1 more source