Ppn2 Polyphosphatase Improves the Ability of S. cerevisiae to Grow in Mild Alkaline Medium [PDF]
Journal of FungiInorganic polyphosphates and respective metabolic pathways and enzymes are important factors for yeast active growth in unfavorable conditions. However, particular proteins of polyphosphate metabolism remain poorly explored in this context.
Irina A. Eliseeva +10 more
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PLoS ONE, 2015 The polyphosphatase PPN1 of Saccharomyces cerevisiae shows an exopolyphosphatase activity splitting phosphate from chain end and an endopolyphosphatase activity fragmenting high molecular inorganic polyphosphates into shorter polymers.
Tatiana Kulakovskaya +1 more
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The Extracellular Vesicles Containing Inorganic Polyphosphate of Candida Yeast upon Growth on Hexadecane [PDF]
Journal of Xenobiotics, 2023 The cell wall of Candida yeast grown on presence of hexadecane as a sole carbon source undergoes structural and functional changes including the formation of specific supramolecular complexes—canals.
Anton N. Zvonarev +6 more
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Activities and genetic interactions of fission yeast Aps1, a Nudix-type inositol pyrophosphatase and inorganic polyphosphatase [PDF]
MBioInositol pyrophosphate 1,5-IP8 regulates expression of a fission yeast phosphate homeostasis regulon, comprising phosphate acquisition genes pho1, pho84, and tgp1, via its action as an agonist of precocious termination of transcription of the upstream ...
Stewart Shuman +2 more
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Polyphosphatases have a polyphosphate-independent influence on the virulence of Cryptococcus neoformans [PDF]
Infection and ImmunityCryptococcus neoformans, an invasive basidiomycete fungal pathogen, causes one of the most prevalent, life-threatening diseases in immunocompromised individuals and accounts for ~19% of AIDS-associated deaths. Therefore, understanding the pathogenesis of
Kabir Bhalla +11 more
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Pull-Down Into Active Inclusion Bodies and Their Application in the Detection of (Poly)-Phosphates and Metal-Ions [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Inclusion bodies are typically ignored as they are considered unwanted protein waste generated by prokaryotic host cells during recombinant protein production or harmful protein inclusions in human cell biology.
Eva Hrabarova +7 more
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Polyphosphate from Lactic Acid Bacteria: A Functional Molecule for Food and Health Applications [PDF]
FoodsThe linear polymer polyphosphate (polyP) is found across all three domains of life and fulfills diverse physiological functions, including phosphorus storage, chaperone activity, and stress tolerance.
Daniela Corrales +3 more
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A Dual-Bacterial Coupled Fermentation Strategy for Nicotinamide Mononucleotide Synthesis [PDF]
Shipin Kexue, 2023 In this study, a dual-bacterial coupled fermentation system containing nicotinamide nucleoside kinase (NRK) and polyphosphatase (PPK) was constructed, and the application of PPK-based ATP regeneration system in NMN production was achieved.
SUN Ting, ZHANG Hongtao, YANG Feng, CHAI Wengang, XUE Haoyang, TAN Shuyin
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Pharmacological inhibition of host pathways enhances macrophage killing of intracellular bacterial pathogens [PDF]
Microbiology SpectrumAfter ingestion into macrophage phagosomes, some bacterial pathogens such as Mycobacterium tuberculosis (Mtb) evade killing by preventing phagosome acidification and fusion of the phagosome with a lysosome.
Ramesh Rijal, Richard H. Gomer
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A systematic study of regulating inorganic polyphosphates production in Saccharomyces cerevisiae [PDF]
Synthetic and Systems BiotechnologyInorganic polyphosphate (polyP), a linear polymer of orthophosphate residues, plays critical roles in diverse biological processes spanning blood coagulation, immunomodulation, and post-translational protein modifications in eukaryotes.
Zipeng Chen +7 more
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