Results 61 to 70 of about 240,390 (129)

Flavonoids: Biosynthesis, Biological functions and Biotechnological applications [PDF]

open access: yes, 2012
Flavonoids are widely distributed secondary metabolites with different metabolic functions in plants. The elucidation of the biosynthetic pathways, as well as their regulation by MYB, bHLH and WD40-type transcription factors, has allowed metabolic ...
Paula eCasati   +14 more
core   +1 more source

Diversity and Evolution of the Phenazine Biosynthesis Pathway [PDF]

open access: yes, 2010
Phenazines are versatile secondary metabolites of bacterial origin that function in biological control of plant pathogens and contribute to the ecological fitness and pathogenicity of the producing strains.
Blankenfeldt, Wulf   +37 more
core   +1 more source

Structure and biosynthesis of fungal secondary metabolites [PDF]

open access: yes, 2013
The root rot pathogen Heterobasidion annosum s.l., i.e. H. abietinum, H. parviporum, H. annosum s.s., H. irregulare and H. occidentale, and the biocontrol fungus Phlebiopsis gigantea were investigated regarding their secondary metabolites.
Hansson, David
core   +1 more source

Exploration of the mechanism of Polyphyllin I against hepatocellular carcinoma based on network pharmacology, molecular docking and experimental validation

open access: yes
Purpose Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Targeted therapies hold promise for HCC treatment, and understanding the molecular mechanisms of action is crucial for developing novel therapeutic strategies ...
Jie Xiong   +5 more
core   +1 more source

Biosynthesis of fucoxanthin and diadinoxanthin and function of initial pathway genes in Phaeodactylum tricornutum [PDF]

open access: yes, 2012
The biosynthesis pathway to diadinoxanthin and fucoxanthin was elucidated in Phaeodactylum tricornutum by a combined approach involving metabolite analysis identification of gene function.
Sandmann, Gerhard   +5 more
core   +1 more source

The biosynthesis of the tropane alkaloid hyoscyamine in datura stramonium [PDF]

open access: yes, 1999
This thesis investigates the biosynthesis of the tropane alkaloid hyoscyamine in Datura stramonium. The biosynthesis of the medicinally important tropane alkaloid hyoscyamine has been investigated for many years.
Wong, Chi W.
core  

Effects of polyphyllin D on the induction of apoptosis in human hepatocellular carcinoma HepG2 cells and its multidrug resistant derivative RHepG2 cells. [PDF]

open access: yes, 2004
Ong Chik Ying Rose.Thesis (M.Phil.)--Chinese University of Hong Kong, 2004.Includes bibliographical references (leaves 181-195).Abstracts in English and Chinese.Acknoledgements --- p.iList of Abbreviations --- p.iiAbstract --- p.iiiAbstract in Chinese

core  

Recent advances in combinatorial biosynthesis for drug discovery [PDF]

open access: yes, 2015
Huihua Sun,1,* Zihe Liu,1,* Huimin Zhao,1,2 Ee Lui Ang1 1Metabolic Engineering Research Laboratory, Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research, Singapore; 2Department of Chemical and Biomolecular ...
Liu Z, Ang EL, Sun H, Zhao H
core  

The biosynthesis of nojirimycins [PDF]

open access: yes
Streptomyces subrutilus ATCC 27467, when grown on a glucosecontaining soyabean medium, produces both 1-deoxymannonojirimycin (DMJ) and 1-deoxynojirimycin (DNJ) in its culture medium.
Hardick, David James
core  

Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice

open access: yes
Objective Smoking was a major risk factor for chronic obstructive pulmonary disease (COPD). This study plan to explore the mechanism of Polyphyllin B in lung injury induced by cigarette smoke (CSE) in COPD.
Hongzhong Yang   +5 more
core   +1 more source

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