CdsA is involved in biosynthesis of glycolipid MPIase essential for membrane protein integration in vivo [PDF]
MPIase is a glycolipid that is involved in membrane protein integration. Despite evaluation of its functions in vitro, the lack of information on MPIase biosynthesis hampered verification of its involvement in vivo. In this study, we found that depletion
IIMURA, Naoki +12 more
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Polyphyllin VII (PP7) inhibited the proliferation of human cancer cells. Cells were treated with increasing concentrations of PP7 for 24 h and cell viability was determined by MTT assay as described in Methods sections. Each IC50 value represents means ±
Yulin Zhang (510822) +11 more
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Fluorophore-appended steroidal saponin (dioscin and polyphyllin D) derivatives
(Chemical Equation Presented) The synthesis of three fluorophore-appended derivatives of dioscin and polyphyllin D is reported herein. Starting from trillin, dansyl derivatives A-C were prepared in overall yields of 7-12% over 7-10 steps.
Wong, ELM +4 more
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Biosynthesis and regulation of cyclic lipopeptides in Pseudomonas fluorescens [PDF]
Cyclic lipopeptides (CLPs) are surfactant and antibiotic metabolites produced by a variety of bacterial genera. For the genus Pseudomonas, many structurally different CLPs have been identified.
Bruijn, I., de
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The average contents of polyphyllin I, II, VII and total steroid saponins in Paris from different geographical regions: (1) Central Yunnan; (2) Northwestern Yunnan; (3) Southwestern Yunnan; (4) Southeastern Yunnan; (5) Guizhou; (6) Guangxi.
Tianjun Yuan (524010) +8 more
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Biosynthesis of Largimycins in Streptomyces argillaceus Involves Transient β‑Alkylation and Cryptic Halogenation Steps Unprecedented in the Leinamycin Family [PDF]
Largimycins A1 and A2 are key members of a recently identified family of hybrid nonribosomal peptide polyketides belonging to the scarcely represented group of antitumor leinamycins.
Becerril García, Adriana +5 more
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Plant sterol metabolism with emphasis on glycoalkaloid biosynthesis in potato [PDF]
Glycoalkaloids are secondary metabolites present within species of the family Solanaceae. They are toxic to humans and animals, and it is important to keep the levels in potato (Solanum tuberosum L.) tubers below the safe limit for consumption ...
Arnqvist, Lisa
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<i>5.9. HPLC method for detecting steroid saponins in P. polyphylla roots</i> <p>For HPLC, an aliquot of the same fresh plant root material that was used for expression analysis was freeze-dried at −50 ̊C for 8 h, and then ...
Gao, Linhui +3 more
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Optimization of ultrasound-assisted extraction of two saponins from Paris polyphylla var. yunnanensis leaves using response surface methodology [PDF]
Paris polyphylla var. yunnanensis is one of the famous Chinese herbs, in which two saponins (polyphyllin II and polyphyllin VII) have anticancer effects. The endangerment of Paris polyphylla var.
Huaxiong Lei +8 more
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The lytB gene of Escherichia coli is essential and specifies a product needed for isoprenoid biosynthesis [PDF]
LytB and GcpE, because they are codistributed with other pathway enzymes, have been predicted to catalyze unknown steps in the nonmevalonate pathway for isoprenoid biosynthesis.
McLennan, Neil +3 more
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