Results 31 to 40 of about 240,390 (129)
A cycloartenol synthase from the steroidal saponin biosynthesis pathway of Paris polyphylla
, 2020 Steroidal saponins named polyphyllin are the major active components of Paris polyphylla. Cycloartenol synthase (CAS) is a key enzyme that catalyzes the formation of the sterol scaffold. In this study, we cloned a putative CAS gene from Paris polyphylla.
Si-Yuan Guo (8542251) +6 more
core +1 more source
, 2021 Nasopharyngeal carcinoma (NPC) is a malignant tumor in southern China, and nano Traditional Chinese Medicine (TCM) represents great potential to cancer therapy.
Xian-Yu Bai +8 more
core +1 more source
Aspergillus westerdijkiae polyketide synthase gene “aoks1” is involved in the biosynthesis of ochratoxin A [PDF]
, 2009 OchratoxinA (OTA) is a potential nephrotoxic, teratogenic, immunogenic, hepatotoxic and carcinogenic mycotoxin, produced by Aspergillus westerdijkiae NRRL 3174.
Atoui, Ali +4 more
core +1 more source
Polyphyllin VII induces apoptosis in HepG2 cells through ROS-mediated mitochondrial dysfunction and MAPK pathways [PDF]
, 2016 Polyphyllin VI (PP6) inhibited the proliferation of human cancer cells (HepG2, A549, MCF7, SKOV3, Hep3B, Bel7402 and 7721). Cells were treated with increasing concentrations of PP6 for 24 h and cell viability was determined by MTT assay as described in ...
Shenghui Chen +23 more
core +1 more source
Chemical structures of polyphyllin I, II, VI and VII.
, 2014 Chemical structures of polyphyllin I, II, VI and VII.
Tianjun Yuan (524010) +8 more
core +1 more source
Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy
Advanced Science, Volume 13, Issue 21, 13 April 2026.Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu +6 more
wiley +1 more source
, 2023 Additional file 3. Cytotoxicity of resatorvid, EUK-134, disulfiram, polyphyllin,and RS 09 TFA toward PAMs. The effects of resatorvid, EUK-134, disulfiram, polyphyllin, and RS 09 TFA on the cellular viability of PAMs were examined using the cell-counting ...
Zebu Song (16536887) +8 more
core +1 more source
Oxidative Medicine and Cellular Longevity, Volume 2026, Issue 1, 2026.Liver diseases, both acute and chronic, are a major global health burden with limited therapeutic options. Ferroptosis, an iron‐dependent form of regulated cell death driven by lipid peroxidation, has emerged as a key contributor to liver pathology and a potential therapeutic target.
Farshad Niazpour +2 more
wiley +1 more source
The Immune Microenvironment in Liver Cancer: From Analysis to Targeting
Advanced Science, Volume 12, Issue 47, December 18, 2025.This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan +5 more
wiley +1 more source
Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications
Cell Proliferation, Volume 58, Issue 10, October 2025.Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su +5 more
wiley +1 more source