Results 21 to 30 of about 240,390 (129)

Data_Sheet_2_Endophyte-inoculated rhizomes of Paris polyphylla improve polyphyllin biosynthesis and yield: a transcriptomic analysis of the underlying mechanism.CSV

open access: yes, 2023
IntroductionPolyphyllin from Paris polyphylla var. yunnanensis exhibits anti-inflammatory, analgesic, antibacterial, and antiviral properties. However, the current production of polyphyllin can barely meet market demand.
Lufeng Liu (16011029)   +9 more
core   +1 more source

Traditional Uses, Active Ingredients, and Biological Activities of Paris polyphylla Smith: A Comprehensive Review of an Important Himalayan Medicinal Plant

open access: yesJournal of Chemistry, Volume 2023, Issue 1, 2023., 2023
Paris polyphylla Smith (family: Melanthiaceae), a high‐value medicinal herb endemic to the Himalayan region, has drawn much attention recently due to its immense use in the traditional healthcare system since ancient times. In the present review, an extensive database on P.
Janhvi Mishra Rawat   +8 more
wiley   +1 more source

Presentation_1_Endophyte-inoculated rhizomes of Paris polyphylla improve polyphyllin biosynthesis and yield: a transcriptomic analysis of the underlying mechanism.pdf

open access: yes, 2023
IntroductionPolyphyllin from Paris polyphylla var. yunnanensis exhibits anti-inflammatory, analgesic, antibacterial, and antiviral properties. However, the current production of polyphyllin can barely meet market demand.
Lufeng Liu (16011029)   +9 more
core   +1 more source

Echinacoside Induces Mitochondria‐Mediated Pyroptosis through Raf/MEK/ERK Signaling in Non‐Small Cell Lung Cancer Cells

open access: yesJournal of Immunology Research, Volume 2022, Issue 1, 2022., 2022
Background. Various natural compounds are effective in cancer prevention and treatment with fewer side effects than conventional radiotherapy and chemotherapy. Considering the uncertainty of the antitumor mechanism of Echinacoside (Ech) and the fact that no study on Ech against non‐small cell lung cancer (NSCLC) has been explored previously, this study
Ye Shi   +5 more
wiley   +1 more source

Mitochondrial Dysfunction Pathway Alterations Offer Potential Biomarkers and Therapeutic Targets for Ovarian Cancer

open access: yesOxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
The mitochondrion is a very versatile organelle that participates in some important cancer‐associated biological processes, including energy metabolism, oxidative stress, mitochondrial DNA (mtDNA) mutation, cell apoptosis, mitochondria‐nuclear communication, dynamics, autophagy, calcium overload, immunity, and drug resistance in ovarian cancer ...
Liang Shen   +2 more
wiley   +1 more source

Anthelmintic Agents from African Medicinal Plants: Review and Prospects

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2022, Issue 1, 2022., 2022
Soil‐transmitted helminthiasis affects more than 1.5 billion people globally and largely remains a sanitary problem in Africa. These infections place a huge economic burden on poor countries and affect livestock production, causing substantial economic losses and poor animal health. The emergence of anthelmintic resistance, especially in livestock, and
Jonathan Jato   +10 more
wiley   +1 more source

RSPH14 regulates the proliferation, cell cycle progression, and apoptosis of non‐small cell lung cancer cells

open access: yesFEBS Open Bio, Volume 11, Issue 10, Page 2715-2726, October 2021., 2021
RSPH14 expression was upregulated in NSCLC samples compared with normal samples and was involved in regulating multiple processes, including glucose transmembrane transport and the AMPK signaling pathway. High expression of RSPH14 enhanced proliferation and cell cycle progression and suppressed the apoptosis of NSCLC cells, thereby promoting the ...
Ke Ma   +9 more
wiley   +1 more source

[Retracted] Microbiome‐Metabolomics Reveals Endogenous Alterations of Energy Metabolism by the Dushen Tang to Attenuate D‐Galactose‐Induced Memory Impairment in Rats

open access: yesBioMed Research International, Volume 2021, Issue 1, 2021., 2021
Aging affects the brain function in elderly individuals, and Dushen Tang (DST) is widely used for the treatment of senile diseases. In this study, the protective effect of DST against memory impairment was evaluated through the Morris water maze (MWM) test and transmission electron microscopy (TEM).
Jifeng Wang   +15 more
wiley   +1 more source

Autophagy Paradox of Cancer: Role, Regulation, and Duality

open access: yesOxidative Medicine and Cellular Longevity, Volume 2021, Issue 1, 2021., 2021
Autophagy, a catabolic process, degrades damaged and defective cellular materials through lysosomes, thus working as a recycling mechanism of the cell. It is an evolutionarily conserved and highly regulated process that plays an important role in maintaining cellular homeostasis.
Amit Kumar Verma   +12 more
wiley   +1 more source

Polyphyllin D Shows Anticancer Effect through a Selective Inhibition of Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP2)

open access: yes, 2021
Natural products have continued to offer tremendous opportunities for drug development, as they have long been used in traditional medicinal systems. SHP2 has served as an anticancer target.
Se Jeong Kwon   +4 more
core   +1 more source

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