Results 11 to 20 of about 240,390 (129)

Additional file 2 of RNA-Seq analysis reveals the important co-expressed genes associated with polyphyllin biosynthesis during the developmental stages of Paris polyphylla

, 2022
Additional file 2: This PDF contains all the additional figures (Figure S1-S6) associated with the manuscript. Figure numbers and titles are listed as follows: Figure S1. BUSCO assessment results. Figure S2. KEGG enrichment analysis of DEGs from 27 paired groups. Figure S3. Ten cluster of DEGs in leaf and the relative KEGG enrichments. Figure S4.
Gao, Xiaoyang, Su, Qixuan, Li, Jing, Yang, Wenjing, Yao, Baolin, Guo, Jiawei, Li, Shengying, Liu, Changning   +7 more
openaire   +2 more sources

Compartment-Specific Variation in Bacterial Microbiome and Polyphyllin Profiles in <i>Paris polyphylla</i>. [PDF]

Int J Microbiol
Paris polyphylla (P. polyphylla) is a valuable traditional Chinese medicinal plant, yet the spatial distribution of its compartment‐specific bacterial microbiomes and their correlative relationships with bioactive polyphyllins remain poorly characterized.
Wu X, Deng Y, Li S, Zou K, Duan Z, Ibrahim N, Zhou J, Jiang L, Liu X, Fu S, Liang Y.   +10 more
europepmc   +2 more sources

Transcriptional Regulation of Polyphyllin Biosynthesis of Paris polyphylla in Response to Soil Moisture Stress

Industrial Crops and Products
Qixuan Su, Changning Liu, Xiaoyang Gao
exaly   +2 more sources

Identification of a bZIP Transcription Factor PpTGA3 Regulating Polyphyllin Biosynthesis in Paris polyphylla

Industrial Crops and Products
Yang Tao, Jin-Yan Zhang, Xiu-Lan Pu
exaly   +2 more sources

Effective prediction of biosynthetic pathway genes involved in bioactive polyphyllins in Paris polyphylla

Communications Biology, 2022
Xin Hua, Wei Song, and ZheYong Xue et al. report an effective method to predict key genes involved in polyphyllin biosynthesis in plants. Their results provide further insight into biosynthesis pathways in Paris polyphylla, and the approach may be ...
Xin Hua, Wei Song, Kangzong Wang, Xue Yin, Changqi Hao, Baozhong Duan, Zhichao Xu, Tongbing Su, Zheyong Xue   +8 more
doaj   +1 more source

ElixirSeeker: A Machine Learning Framework Utilizing Fusion Molecular Fingerprints for the Discovery of Lifespan-Extending Compounds. [PDF]

Aging Cell
ElixirSeeker is a machine learning architecture based on a phenotype‐driven drug discovery approach to screen lifespan‐extending compounds. By integrating molecular fingerprints, ElixirSeeker could maximize feature capture of lifespan‐extending compounds.
Pan Y, Cai H, Ye F, Xu W, Huang Z, Zhu J, Gong Y, Li Y, Ezemaduka AN, Gao S, Liu S, Li G, Li H, Yang J, Ning J, Xian B.   +15 more
europepmc   +2 more sources

Phytobioactive compounds as therapeutic agents for human diseases: A review

Food Science &Nutrition, Volume 11, Issue 6, Page 2500-2529, June 2023., 2023
Phytobioactive compounds are plant secondary metabolites and have remarkable therapeutic potential. Polyphenols, alkaloids, terpenes, and polysaccharides isolated from medicinal plants showed remarkable antioxidant, anticancer, cytotoxic, anti‐inflammatory, cardioprotective, hepatoprotective, immunomodulatory, neuroprotective, and antidiabetic ...
Muhammad Riaz, Ramsha Khalid, Muhammad Afzal, Fozia Anjum, Hina Fatima, Saadiya Zia, Ghulam Rasool, Chukwuebuka Egbuna, Andrew G. Mtewa, Chukwuemelie Zedech Uche, Muhammad Aamir Aslam   +10 more
wiley   +1 more source

Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling

Medicinal Research Reviews, Volume 43, Issue 3, Page 614-682, May 2023., 2023
Abstract Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight cancer and overcome drug resistance in antitumor therapy. Understanding the molecular interactions and structural features of ferroptosis‐inducing compounds might ...
Solveigh C. Koeberle, Anna P. Kipp, Hermann Stuppner, Andreas Koeberle   +3 more
wiley   +1 more source

Data_Sheet_1_Endophyte-inoculated rhizomes of Paris polyphylla improve polyphyllin biosynthesis and yield: a transcriptomic analysis of the underlying mechanism.CSV

, 2023
IntroductionPolyphyllin from Paris polyphylla var. yunnanensis exhibits anti-inflammatory, analgesic, antibacterial, and antiviral properties. However, the current production of polyphyllin can barely meet market demand.
Lufeng Liu (16011029), Ying Yang (24175), Qing Zhang (1802), Tao Liu (10785), Yumei Dong (819762), Congfang Xi (17303854), Sheng Chang (649642), Yu Liu (6938), Yunchao He (17303857), Bo Cai (62436)   +9 more
core   +1 more source

Polyphyllin I Effects Candida albicans via Inhibition of Virulence Factors

Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Paris polyphylla is often used in Chinese medicine to treat conditions such as carbuncles, trauma, snake bites, and mosquito bites. In the present study, we investigated the effect and mechanism of the morphological transition and extracellular phospholipase activity of Candida albicans treated with polyphyllin I (PPI).
Ai-Mei Sun, Ying-Xian Wang, Guo-Xian Hu, Li Li, Rui-Rui Wang, Mohd Adnan   +5 more
wiley   +1 more source