Results 161 to 170 of about 54,552 (286)

Polyploid and Chromosomal Copy Number Gain Cells in Metastatic Colon Cancer: Exploratory Genotype-Phenotype Correlations. [PDF]

Cancers (Basel)
Ottaiano A, Zito Marino F, Ianniello M, Ciappina G, Toscano E, Ieni A, Lucà S, Sirica R, Maiorana E, Berretta S, Di Carluccio N, Caraglia M, Savarese G, Franco R, Berretta M.   +14 more
europepmc   +1 more source

High‐Quality Chromosome‐Level Genomes Reveal the Structure and Evolution of the S and Z Self‐Incompatibility Loci in Leymus chinensis

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3279-3281, May 2026.
Sijie Sun, Jianli Wang, Yu Guan, Hongkui Zhang, Linlin Mu, Xu Zhuang, Dongmei Zhang, Sizhong Li, Mengjie Zhao, Zhelong Lin, Shuaibin Zhang, Xiaofeng Cao, Youfa Cheng, Zhongbao Shen, Yu'e Zhang, Yongbiao Xue   +15 more
wiley   +1 more source

Tn‐seq of Thermus thermophilus Genome Reveals Unexpected Tolerance to Insertions in Bacterial Common Essential Genes

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
Tn‐seq analysis of Thermus thermophilus genome reveals insertions in almost all genes, this is, there is no clear discrimination of essential genes. A similar result has not been reported in other Tn‐seq analysis of bacterial genomes so far. The polyploidy of the Thermus genome could explain the apparent non‐essentiality of key genes.
Cristina L. Gómez‐Campo, Marc Gost, Bruna Fernanda Silva de Sousa, Laura Álvarez, José Berenguer, Modesto Redrejo‐Rodríguez, Mario Mencía   +6 more
wiley   +1 more source

Tetraploids or polyploid giants: who is truly dangerous? [PDF]

Trends Cell Biol
Bloomfield M, Vora S, Epa D, Gabrielli B, Cimini D.   +4 more
europepmc   +1 more source

Dual Targeting of DNA and EGFR by ZYH005 Induces DNA Damage and Mitotic Catastrophe in Glioblastoma

MedComm, Volume 7, Issue 4, April 2026.
ZYH005 exerts potent anti‐glioblastoma activity through a dual mechanism: intercalation‐mediated DNA damage and targeted inhibition of EGFR, leading to cell cycle arrest and mitotic catastrophe. ABSTRACT Glioblastoma multiforme (GBM) is an aggressive, therapy‐resistant brain tumor with limited treatment options.
Jianzheng Huang, Zijun Zhang, Yang Xiao, Ziming Zhao, Zengwei Luo, Junjun Liu, Suitian Lai, Chao Song, Shouchang Feng, Suojun Zhang, Xingjiang Yu, Qingyi Tong, Yonghui Zhang   +12 more
wiley   +1 more source

The role of plant polyploidy in the structure of plant-pollinator communities. [PDF]

Front Plant Sci
Zylberberg I, Halabi K, Ecker N, Streher NS, Pupko T, Ashman TL, Mayrose I.   +6 more
europepmc   +1 more source

Epigenetics—Innovations and Misconceptions

Natural Sciences, Volume 6, Issue 2, April 2026.
ABSTRACT Epigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in the regulation and perpetuation of gene activity states.
Bernhard Horsthemke
wiley   +1 more source

Polyploidy and Mutagenic Germplasm Innovation in Minor Legumes: Paradigm Shift and Challenges from Model Crops to Mung Bean. [PDF]

Plants (Basel)
Guo F, Ma C, Liu Y, Wang L, Li C.
europepmc   +1 more source

CRISPR/Cas Genome Editing and Its Applications in Cereal Crop Improvement

Plant-Environment Interactions, Volume 7, Issue 2, April 2026.
ABSTRACT CRISPR/Cas‐based genome editing has emerged as a transformative tool for precise genetic improvement of cereal crops. Recent advances in CRISPR technologies, including Cas9, Cas12, Cas13, base editing, and prime editing, have enabled targeted modification of genes and regulatory elements controlling yield, stress tolerance, and grain ...
Sirisha Kaniganti, Himanshu Saini, A. K. Chaitanya, Niranjan Hegde, Priya Shah, Nakul D. Magar, Ramesh Rijal, Jeevan Jyoti Kaushik, Deepak Nanda, Sharad Sachan, Anand Kumar, Roopali Bhoite, Harsha Rayudu Jamedar   +12 more
wiley   +1 more source

Polyploid plant genomes complexity and the challenges of sequencing. [PDF]

Planta
Anderson AW, Albertini E, Rosellini D.
europepmc   +1 more source