Results 101 to 110 of about 7,524 (195)

Association of HRD Score With Efficacy of Neoadjuvant Short‐Course Radiotherapy Plus Sequential Chemoimmunotherapy in pMMR Locally Advanced Rectal Cancer

open access: yesCancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Homologous recombination deficiency (HRD) has been reported to be associated with increased sensitivity to platinum‐based treatment and radiotherapy in some solid tumors. Aim This study investigated the correlation between HRD score and treatment response to neoadjuvant short‐course radiotherapy combined with sequential chemotherapy
Xin Ran   +15 more
wiley   +1 more source

Graft Biology in the CRISPR Era: From Tissue Fusion to Genome Compatibility [PDF]

open access: yesPlant Environ Interact
ABSTRACT Plant lineage has traditionally constrained grafting compatibility, with monocots generally considered incompatible because of their dispersed vascular bundles and limited secondary growth. Recent studies have shown that embryonic grafting can establish successful graft unions in selected monocot systems by exploiting early developmental ...
Sahaja M   +5 more
europepmc   +2 more sources

Polyploid induction of Eucalyptus dunnii Maiden to generate waviability in breeding programs. [Polyploid induction of Eucalyptus dunnii Maiden to generate variability in breeding programs].

open access: yes, 2022
Eucalyptus dunnii Maiden produces good quality cellulose pulp, showing good frost tolerance. However, in Uru-guay, it needs more than six years to reach the reproductive stage. Genome duplication was proposed as a strategy to obtain useful variability. The application of mitosis inhibitors for chromosomal duplication, in explants growing in vitro, was ...
CASTILLO, A.   +4 more
openaire   +1 more source

Wheat Wild Relatives and Modern Cultivars Differ for Salt Resistance in Terms of Morpho‐Physiological Traits

open access: yesJournal of Plant Nutrition and Soil Science, Volume 189, Issue 5, Page 721-734, October 2026.
Wheat wild relatives are untapped genetic resources from salinity and drought hit areas. This study presents differential comparative morphophysiological responses of these species and modern wheat cultivars under saline conditions. Salt resistant species produce more shoot and root biomass under saline conditions through salt exclusion and/or tissue ...
Muhammad Saqib, Riya Raj, Michael Frei
wiley   +1 more source

Colchicine-Induced Polyploidy in Edible Cactus [Opuntia ficus-indica (L.) Mill.]: Impact on Biological Traits and Bioactive Compound Accumulation

open access: yesHorticulturae
Opuntia ficus-indica (OFI) is a cactus species of considerable economic importance in agriculture and various nutritional applications. We aimed to establish a feasible method for polyploid induction in OFI using colchicine treatment, as well as to ...
Natthakitti Boonnak   +3 more
doaj   +1 more source

Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment

open access: yesMedComm, Volume 7, Issue 10, October 2026.
This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen   +9 more
wiley   +1 more source

Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Yao Wang   +9 more
wiley   +1 more source

In vitro induction and regeneration of tetraploids and mixoploids of two cassava cultivars

open access: yesCrop Breeding and Applied Biotechnology, 2018
We report the in vitro induction of polyploids from two cassava cultivars by colchicine treatment. Shoot nodal segments, collected from in vitro cultivated plants of Porquinho and Vassourinha cultivars, were used as explants.
Mateus Mondin   +3 more
doaj  

A Trp574–Leu substitution confers resistance to three classes of acetolactate synthase inhibitors in Australian brome grass (Bromus diandrus)

open access: yesPest Management Science, Volume 82, Issue 10, Page 9437-9443, October 2026.
Target‐site based imidazolinone resistance in brome grass was found to be conferred by a mutation at position 574 in the ALS gene and to severely impact the efficacy of the herbicide Intervix®, a co‐formulation of imazamox and imazapyr. Abstract BACKGROUND Brome grass (Bromus diandrus) is a prevalent weed in southern Australian cropping regions which ...
Roberto Busi   +5 more
wiley   +1 more source

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