Results 61 to 70 of about 7,524 (195)

Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells

Cell Proliferation, EarlyView.
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley   +1 more source

Disease suppression and growth enhancement in colchicine-treated putative polyploid emprit ginger against Ralstonia solanacearum

Jurnal Ilmiah Pertanian
Bacterial wilt caused by Ralstonia solanacearum remains a major constraint in emprit ginger cultivation, while conventional control strategies are often ineffective and limited by the narrow genetic variability of vegetatively propagated planting ...
Andree Wijaya Setiawan, Ruth Meike Jayanti, Yuliana Pratiwi Asti   +2 more
doaj   +1 more source

Induction of Polyploid Tillered Onion using Colchicine and Pendimethalin

Sains Malaysiana, 2018
The shoot tip explants of the tillered onion line Z-018 were used as experimental materials. The effects of colchicine and pendimethalin on the induction of polyploid tillered onion were studied in vitro with different concentrations and treatment time. Treatment with 250 μmol/L colchicine for 4 days caused a variant rate of 42.22% and a mortality rate
Jian Ren, Xiaoxu Wu, Ce Song, Yu Liang, Wenzheng Gao, Yong Wang   +5 more
openaire   +1 more source

Ploidy‐dependent modulation of DNA replication kinetics in Xenopus

The FEBS Journal, EarlyView.
Using an interspecies replication system with Xenopus frog species of different ploidy levels, we investigated how DNA replication adapts to polyploidization. While replication was slower in tetraploid than in diploid nuclei, dodecaploid nuclei unexpectedly replicated faster than tetraploid nuclei. Our findings show that increasing genome size does not
Hemalatha Narassimprakash, Olivier Haccard, Zhen Li, Nicolas Pollet, Kathrin Marheineke   +4 more
wiley   +1 more source

Polyploid induction of Eucalyptus dunnii Maiden to generate variability in breeding programs

Agrociencia, 2020
Eucalyptus dunnii Maiden produces good quality cellulose pulp, showing good frost tolerance. However, in Uruguay, it needs more than six years to reach the reproductive stage.
Alicia Castillo, Valeria López, Elena Tavares, Federico Santiñaque, Marco Dalla Rizza   +4 more
doaj   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Artificial polyploidy as a tool for improving growth and stress resilience in tree species

Frontiers in Forests and Global Change
Woody trees are invaluable to ecosystems and economies, providing essential resources such as timber, fuel, food, and medicine. Trees also play a critical role in carbon sequestration, biodiversity conservation, and soil stabilization, making their ...
Rohit Bharati, Lucie Severová
doaj   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

Polyploid induction of Luculia pinceana Hook. by aseptic germination combined with chemical agents

European Journal of Horticultural Science
Summary To obtain polyploid Luculia pinceana Hook., chemical mutagenesis, tissue culturing and rapid propagation technology were used, and the resulting germplasm may be bred to produce new varieties. The seeds of L.
Lele Wang, Yefang Li, Xiaoyu Lu, Shifeng Li, Jie Song, Wenling Guan   +5 more
doaj   +1 more source

Recent advances in the genomics of sugarcane (Saccharum)

Journal of Integrative Plant Biology, EarlyView.
This review systematically summarizes advances in sugarcane genomics, evolution, classification, and breeding practices. It identifies key research bottlenecks and proposes an integrated research framework to facilitate predictive sugarcane breeding, which provides valuable references for genetic improvement of other complex polyploid crops.
Tianyou Wang, Qin Zhang, Qiutao Xu, Han Zhao, Zhen Li, Jisen Zhang   +5 more
wiley   +1 more source