Results 111 to 120 of about 28,869 (295)

TriPoly: haplotype estimation for polyploids using sequencing data of related individuals

Bioinform., 2018
Motivation Knowledge of haplotypes, i.e. phased and ordered marker alleles on a chromosome, is essential to answer many questions in genetics and genomics.
E. Motazedi, D. Ridder, R. Finkers, Samantha J. Baldwin, Susan J. Thomson, Katrina S. Monaghan, C. Maliepaard   +6 more
semanticscholar   +1 more source

PTEN homozygous deletion is a negative prognostic factor in tumor treating fields‐treated glioblastoma, IDH wildtype patients

Brain Pathology, EarlyView.
In a molecularly confirmed cohort of 64 newly diagnosed, TTFields‐treated glioblastomas, IDH‐wildtype, homozygous PTEN deletion was associated with markedly shorter overall survival (368 vs. 603 days) and remained an independent adverse prognostic factor.
Jakob Nückles, Claudius Jelgersma, Christin Siewert, Brendan Osberg, Simone Schmid, Arend Koch, Eilís Perez, Daniel Teichmann, Martin Misch, Anna‐Gila Karbe, Susanne Ukrow, Patrick N. Harter, Ruth M. Stassart, Peter Vajkoczy, Julia Onken, David Capper   +15 more
wiley   +1 more source

Ecological and evolutionary implications of hybridization, polyploidy and apomixis in angiosperms

Botan‪ical Sciences
Hybridization, polyploidy, and apomixis are related to the diversification of angiosperms, generating complex taxonomic relationships between species. Despite the differences in the frequencies of these phenomena, apomixis, the asexual seed production ...
Cinthya I. Cervantes-Díaz, Ken Oyama, Eduardo Cuevas   +2 more
doaj   +1 more source

Evolution of Gene Expression Balance Among Homeologs of Natural Polyploids

G3: Genes, Genomes, Genetics, 2017
Polyploidy is a major evolutionary process in eukaryotes, yet the expression balance of homeologs in natural polyploids is largely unknown. To study this expression balance, the expression patterns of 2180 structurally well-characterized genes of wheat ...
Jasdeep S. Mutti, Ramanjot K. Bhullar, K. Gill   +2 more
semanticscholar   +1 more source

Evolutionary framework and tribal circumscription of Amaranthaceae sensu stricto based on a comprehensive phylogenomic analysis

Cladistics, EarlyView.
Abstract The evolutionary history of Amaranthaceae sensu stricto (s.s.) has been shaped by multiple whole‐genome duplications and rapid radiations, producing an ecologically diverse lineage whose internal relationships have long remained unresolved.
Tina Kiedaisch, Anže Žerdoner Čalasan, Ross A. McCauley, Gudrun Kadereit   +3 more
wiley   +1 more source

Evolution of population size of polyploids and non-polyploids with respect to food energy availability in four individual experiments under a scenario of fixed food reduction.

, 2019
30% (A and B) or 90% (C and D), respectively, of the food was removed at time step 300. Simulations start with a population of 200 non-polyploid DOs, which evolve under a WGD rate set at 40%.
Yves Van de Peer (3785), Yao Yao (335996), Lorenzo Carretero-Paulet (106414)   +2 more
core   +1 more source

Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells

Cell Proliferation, EarlyView.
Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley   +1 more source

Reproductive pathways in Hieracium s.s. (Asteraceae): strict sexuality in diploids and apomixis in polyploids

Annals of Botany, 2018
Background and Aims Apomixis or asexual seed reproduction is a key evolutionary mechanism in certain angiosperms providing them with reproductive assurance and isolation.
P. Mráz, P. Zdvořák
semanticscholar   +1 more source

1175. Madeirina macrorhiza (Lowe ex Hooker) D. J. Crawford, M. Seq., Mort & J. K. Kelly, gen. nov. et comb. nov.

Curtis's Botanical Magazine, EarlyView.
Summary Tolpis Adanson is a genus of some 15 species distributed primarily in the Macaronesian archipelagos of the Azores, Canary Islands, Madeira, and Cape Verde Islands. A phylogenomic study resolved Tolpis as monophyletic with the Madeiran endemic species Tolpis macrorhiza sister to the remainder of the genus.
Daniel J. Crawford, Miguel Menezes de Sequeira, Mark E. Mort, Benjamin Kerbs, John K. Kelly, Christine Battle   +5 more
wiley   +1 more source

Exploiting Next Generation Sequencing to solve the Haplotyping puzzle in Polyploids

, 2016
Evaluation of single genome haplotyping methods in polyploids through a simulation ...
Ehsan Motazedi (2637544)
core   +1 more source