Results 71 to 80 of about 30,417 (268)

Purpurin Alleviates Chemotherapy‐Induced Thrombocytopenia Through Estrogen Receptor α Dependent Phosphoinositide 3‐Kinase/Protein Kinase B Signalling

Phytotherapy Research, EarlyView.
Schematic overview of the in vitro and in vivo evaluation of purpurin in promoting MK maturation and platelet production, through ESR1/PI3K/AKT. ABSTRACT Chemotherapy‐induced thrombocytopenia (CIT) increases bleeding risk and compromises chemotherapy delivery.
Xiaolin Gan, Xinle Wang, Lu Hao, Xiaoqin Tang, Zhixuan Liu, Long Wang, Xiang Xie, Xiang Li, Chunling Zhao, Yan Li, Xinwu Huang, Yuanzhi Liu, Jianming Wu   +12 more
wiley   +1 more source

Cytogenotoxic and Molecular Assessment of Pyrethrins on Non‐Target Allium cepa Roots

Environmental Toxicology, EarlyView.
ABSTRACT The pyrethrins, which form a part of naturally occurring insecticidal chemicals derived from chrysanthemum flowers, not only provide rapid knockdown of a broad spectrum of insect pests but are also widely used in integrated pest management due to a generally favorable safety profile, largely attributed to low mammalian toxicity.
Yudum Yeltekin Uğur, Rahsan Ilikci‐Sagkan, Recep Liman   +2 more
wiley   +1 more source

Brassica diversity through the lens of polyploidy: genomic evolution, introgression, and homoeologous exchange

Horticultural Plant Journal
Polyploidy, or whole-genome duplication, is an important evolutionary process that has shaped the genomes and traits of many plants, including numerous important crops.
Tianpeng Wang, Aalt D.J. van Dijk, Xu Cai, Jian Wu, Guusje Bonnema, Xiaowu Wang   +5 more
doaj   +1 more source

Wider geographic distribution and higher diversity of hexaploids than tetraploids in Carassius species complex reveal recurrent polyploidy effects on adaptive evolution

Scientific Reports, 2017
Polyploidy roles on adaptive evolution and ecological novelty have been extensively studied in plants but remained unclear in vertebrates owing to the rare polyploidy incidences.
Xiao-Li Liu, Fang-Fang Jiang, Zhong-Wei Wang, Xi-Yin Li, Zhi Li, Xiao-Juan Zhang, Fan Chen, Jian-Feng Mao, Li Zhou, Jian-Fang Gui   +9 more
doaj   +1 more source

Divergence Linked to Possible Ecological Speciation in Blind Mole Rats: Integration of Thermal Biology and Bite Force in the Upper Galilee Blind Mole Rat (Nannospalax galili)

Integrative Zoology, EarlyView.
Basalt‐dwelling blind mole rats maintain lower body temperatures, show greater post‐digging thermal increases, and dig more efficiently than those from rendzina soils. Although metabolic rates and bite force did not differ between populations, these thermal and physiological shifts align with the greater mechanical resistance and seasonal hypoxia of ...
Matěj Lövy, Jan Okrouhlík, František Vejmělka, Pavlína Schwarzová, Maja Rendulić, Eviatar Nevo, Radim Šumbera   +6 more
wiley   +1 more source

The association between polyploidy and clonal reproduction in the angiosperms. [PDF]

, 2018
Polyploidy, the presence of 3 or more chromosome sets, is widespread throughout the flowering plants (angiosperms). Asexuality through clonal reproduction is predicted to promote polyploid evolution and establishment in natural populations, but there is ...
Van Drunen, Wendy
core   +1 more source

Creating insect neopolyploid lines to study animal polyploid evolution

Evolutionary Applications
Whole‐genome duplication (polyploidy) poses many complications but is an important driver for eukaryotic evolution. To experimentally study how many challenges from the cellular (including gene expression) to the life history levels are overcome in ...
Saminathan Sivaprakasham Murugesan, Leo W. Beukeboom, Eveline C. Verhulst, Kelley Leung   +3 more
doaj   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Comparative Evidence for the Correlated Evolution of Polyploidy and Self-compatibility in Solanaceae [PDF]

, 2012
Whole genome duplication, or polyploidy, is especially common among flowering plants and has numerous phenotypic and genotypic consequences (Ramsey and Schemske, 1998; Otto and Whitton, 2000). Of particular importance is the effect of polyploidy on plant
Kelly A. Robertson (7973822)
core   +2 more sources

A CCNA1 Missense Variant Associated With Chromatid Non‐Disjunction in Abnormal‐Headed Sperm and Male Infertility

Andrology, EarlyView.
ABSTRACT Background Macrozoospermia is a rare form of teratozoospermia characterized by tetraploids, large‐headed spermatozoa with multiple flagella, usually caused by bi‐allelic AURKC mutations. The etiology of atypical phenotypes with a lower proportion of large headed spermatozoa and single flagella however often remains unresolved.
Aurore Perrin, Frédéric Morel, Zeina Wehbe, Cynthia Frapsauce, Nadia Gueganic, Corinne Tous, Séverine Commet, Laura Dijols, Audrey Basinko, Nathalie Douet‐Guilbert, Célia Tebbakh, Zine‐Eddine Kherraf, Pierre F. Ray, Charles Coutton, Guillaume Martinez   +14 more
wiley   +1 more source