Results 41 to 50 of about 3,251 (110)

The role of circRNA polyribonucleotide nucleoside transferase 1 on Gestational Diabetes Mellitus.

Cellular and Molecular Biology, 2022
This study aimed to focus on the mechanism of circRNA polyribonucleotide nucleoside transferase 1 (circ-PNPT1)-mediated miR-889-3p/PAK1 on gestational diabetes mellitus (GDM).
Xiaolu Chen, Jiaou Huang, Yangying Peng, Yu Han, Xiaoyan Wang, C. Tu   +5 more
semanticscholar   +1 more source

AGO1x prevents dsRNA-induced interferon signaling to promote breast cancer cell proliferation

bioRxiv, 2019
Initially reported for viral RNA, elongation of polypeptide chains beyond the stop codon (translational readthrough (TR)) also occurs on eukaryotic transcripts. TR diversifies the proteome and can modulate protein levels 1-6. Here we report that AGO1x, a
Souvik Ghosh, Joao C. Guimaraes, Manuela Lanzafame, A. Schmidt, Afzal P. Syed, Beatrice Dimitriades, Anastasiya Börsch, Shreemoyee Ghosh, A. L. Correia, Johannes Danner, G. Meister, L. Terracciano, S. Piscuoglio, M. Zavolan   +13 more
semanticscholar   +1 more source

Identification of a novel aminoglycoside O-nucleotidyltransferase AadA33 in Providencia vermicola

Frontiers in Microbiology, 2022
A novel chromosome-encoded aminoglycoside O-nucleotidyltransferase AadA33 was identified in Providencia vermicola strain P13. The AadA33 shares the highest amino acid identity of 51.28% with the function characterized AadA31.
Chunling Feng, Mengdi Gao, Wei-Ming Jiang, Weina Shi, Anqi Li, Shuang Liu, Lei Zhang, Xueya Zhang, Qiaoling Li, Hailong Lin, Junwan Lu, Kewei Li, Hailin Zhang, Yunliang Hu, Qiyu Bao, Xi Lin   +15 more
semanticscholar   +1 more source

Pnpt1 mediates NLRP3 inflammasome activation by MAVS and metabolic reprogramming in macrophages

bioRxiv, 2022
C. Hsu, Wenjia Li, M. Sowden, Camila Lage Chávez, B. Berk   +4 more
semanticscholar   +1 more source

Nucleotidyltransferase toxin MenT extends aminoacyl acceptor ends of serine tRNAs to control Mycobacterium tuberculosis growth

Nature Communications
Toxins of toxin-antitoxin systems use diverse mechanisms to inhibit bacterial growth. In this study, we characterize the translation inhibitor toxin MenT3 of Mycobacterium tuberculosis, the bacterium responsible for tuberculosis in humans.
Xibing Xu, Roland Barriot, Bertille Voisin, Tom J. Arrowsmith, B. Usher, Claude Gutierrez, Xue Han, Carine Pagès, Peter Redder, T. R. Blower, O. Neyrolles, P. Genevaux   +11 more
semanticscholar   +1 more source

Substrate specificity of Mycobacterium tuberculosis tRNA terminal nucleotidyltransferase toxin MenT3

Nucleic Acids Research
Mycobacterium tuberculosis transfer RNA (tRNA) terminal nucleotidyltransferase toxin, MenT3, incorporates nucleotides at the 3′-CCA end of tRNAs, blocking their aminoacylation and inhibiting protein synthesis.
Jun Liu, Y. Yashiro, Y. Sakaguchi, Tsutomu Suzuki, Kozo Tomita   +4 more
semanticscholar   +1 more source

Inducible auto-phosphorylation regulates a widespread family of nucleotidyltransferase toxins

Nature Communications
Nucleotidyltransferases (NTases) control diverse physiological processes, including RNA modification, DNA replication and repair, and antibiotic resistance.
Tom J. Arrowsmith, Xibing Xu, Shangze Xu, B. Usher, Peter Stokes, Megan Guest, Agnieszka K. Bronowska, P. Genevaux, T. R. Blower   +8 more
semanticscholar   +1 more source

Depletion of tRNA CCA-adding enzyme in Mycobacterium tuberculosis leads to polyadenylation of transcripts and precursor tRNAs. [PDF]

Sci Rep, 2023
Błaszczyk E, Płociński P, Lechowicz E, Brzostek A, Dziadek B, Korycka-Machała M, Słomka M, Dziadek J.   +7 more
europepmc   +1 more source

Draft Genome Sequence of Enterococcus dispar CoE-457-22, Isolated from Traditionally Produced Montenegrin Dry Sausage. [PDF]

Microbiol Resour Announc, 2023
Daza Prieto B, Raicevic N, Ladstätter J, Hyden P, Jovanovic A, Stöger A, Cabal Rosel A, Mach RL, Ruppitsch W, Martinovic A.   +9 more
europepmc   +1 more source

Molecular events confirming antimutagenicity to abscisic acid derived from a floral honey establishing its functional relevance. [PDF]

Heliyon, 2022
Saxena S, Gautam S.
europepmc   +1 more source