Results 121 to 130 of about 1,913 (163)

Interaction of ribosomes and natural polyribonucleotides

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects, 1963
Abstract The tendency of natural polyribonucleotides to associate with ribosomes was exmanied under experimental conditions similar to those employed in a previous study which made use of synthetic polyribonucleotides. Ribosomal RNA and “pulse” RNA prepared from Escherichia coli infected with T 2 -phage were the natural polyribonucleotides used ...
T, OKAMOTO, M, TAKANAMI
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Interaction of ribosomes and synthetic polyribonucleotides

Journal of Molecular Biology, 1963
Studies were carried out on the interaction between E. coli ribosomes and a variety of synthetic polyribonucleotides. Among the synthetic polymers tested, poly-U,† poly-UC (1 : 2, 2 : 1) and NaNO 2 -treated poly-C showed a strong interaction with ribosomes and formed heavy complexes in the sedimentation analysis.
M, TAKANAMI, T, OKAMOTO
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Fluorescent conjugates of biosynthetic polyribonucleotides

Biochimica et Biophysica Acta (BBA) - Biophysics including Photosynthesis, 1965
Abstract The polarization and intensity of fluorescence of acriflavine conjugates of the polyribonucleotides are very dependent upon their physical state and show pronounced changes for the helix → coil transitions which have been identified. The conversion to the helical form always results in an increase of apparent relaxation time. The temperature
D B, Millar, R F, Steiner
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Polyribonucleotides Containing a Phosphorothioate Backbone

European Journal of Biochemistry, 1970
The enzymatic synthesis of two polyribonucleotides, poly r(s̄As̄U) and poly r(s̄U) containing a sugar‐phosphorothioate instead of a sugar‐phosphate backbone, is described. The formation and thermal stability of double‐stranded polymers is not impaired by this modification. They can also serve as templates for RNA‐polymerase.
F, Eckstein, H, Gindl
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Degradation of polyribonucleotides: Biocatalysis and the monitoring of products

Applied Biochemistry and Microbiology, 2014
Macroporous monolithic material containing covalently linked ribonuclease A was used to create high-performance flow heterogeneous biocatalysts (bioreactors). The kinetic parameters of the degradation of polycytidylic acid were identified, and the properties of the obtained systems were compared. A HPLC method has been developed for monitoring products
E G, Vlakh, M V, Volokitina, D O, Vinokhodov, T B, Tennikova   +3 more
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Photosensitized reaction of polyribonucleotides

Journal of Molecular Biology, 1965
It had previously been shown that the primary effect of the photosensitized oxidation of DNA and RNA was the preferential destruction of the guanine residue. With synthetic polyribonucleotides, absorbance changes occur only in those polymers which contain guanine. The capacity of guanine-containing polyribonucleotides to direct either the incorporation
Melvin I. Simon, Lawrence Grossman, Helen Van Vunakis   +2 more
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Polyribonucleotides containing thiopurines: Synthesis and properties

Biochemical and Biophysical Research Communications, 1976
Abstract The synthesis of poly(1-methyl-6-thioinosinic acid) and a comparison of its properties with those of poly(6-thioinosinic acid) and poly(6-methylthiopurinylic acid) are reported. In contrast to 6-thioinosine 5′-diphosphate, 1-methyl-6-thioinosine 5′-diphosphate was found to be a substrate for polynucleotide phosphorylase-catalyzed ...
A D, Broom, V, Amarnath
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Characterization of immune suppression induced by polyribonucleotides

International Journal of Immunopharmacology, 1991
Synthetic polyribonucleotide complexes, which have been shown to be potent adjuvants to the immune response of animals and humans were tested for their capacity to activate cells involved in suppressing antibody synthesis. Poly A:poly U and poly I:poly C inhibited murine antibody forming spleen cells when given 1-6 days before antigenic stimulus.
M J, Odean, G J, Trachte, A G, Johnson
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The adsorption of polyribonucleotides

Biopolymers, 1964
AbstractUsing a chromatographic technique, the adsorption of the polyribonucleotides s‐RNA and poly‐A provided with tri‐n‐butylammonium ions from an aqueous solution on to the surface of polymeric hydrocarbon granules has been demonstrated. The aqueous solution from which adsorption takes place is the aqueous phase which results on agitating together n‐
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Some hydrodynamic and optical properties of polyribonucleotides

Biophysical Chemistry, 1973
Abstract The size and shape of four polyribonucleotides were studied by sedimentation and viscosity measurements. The results were correlated with their conformations based on optical activity studies. Polyriboadenylic acid in acidic solution dimerizes into two double-stranded forms, one with half-protonated bases and the other fully protonated.
G C, Chen, J T, Yang
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