Results 61 to 70 of about 225,549 (221)

The O-specific polysaccharide lyase from the phage LKA1 tailspike reduces Pseudomonas virulence [PDF]

Scientific Reports, 2017
AbstractPseudomonas phage LKA1 of the subfamily Autographivirinae encodes a tailspike protein (LKA1gp49) which binds and cleaves B-band LPS (O-specific antigen, OSA) of Pseudomonas aeruginosa PAO1. The crystal structure of LKA1gp49 catalytic domain consists of a beta-helix, an insertion domain and a C-terminal discoidin-like domain.
Olszak, Tomasz, Shneider, Mikhail M., Latka, Agnieszka, Maciejewska, Barbara, Browning, Christopher, Sycheva, Lada V., Cornelissen, Anneleen, Danis - Wlodarczyk, Kasia, Senchenkova, Sofya N., Shashkov, Alexander S., Gula, Grzegorz, Arabski, Michal, Wasik, Slawomir, Miroshnikov, Konstantin A., Lavigne, Rob, Leiman, Petr G., Knirel, Yuriy A., Drulis-Kawa, Zuzanna   +17 more
openaire   +2 more sources

Cell aggregation is associated with enzyme secretion strategies in marine polysaccharide-degrading bacteria

The ISME Journal, 2023
Polysaccharide breakdown by bacteria requires the activity of enzymes that degrade polymers either intra- or extra-cellularly. The latter mechanism generates a localized pool of breakdown products that are accessible to the enzyme producers themselves as
Glen D'souza, A. Ebrahimi, A. Stubbusch, Michael Daniels, J. Keegstra, R. Stocker, O. Cordero, M. Ackermann   +7 more
semanticscholar   +1 more source

A comparative study of the efficacy of alginate lyases in the presence of metal ions elevated in the cystic fibrosis lung milieu

Biochemistry and Biophysics Reports
Pseudomonas aeruginosa, a common cause of morbidity in cystic fibrosis, chronically infects the patient's lungs by forming an alginate-containing biofilm.
Neetu, T.N.C. Ramya
doaj   +1 more source

Capturing single cell genomes of active polysaccharide degraders: an unexpected contribution of Verrucomicrobia. [PDF]

PLoS ONE, 2012
Microbial hydrolysis of polysaccharides is critical to ecosystem functioning and is of great interest in diverse biotechnological applications, such as biofuel production and bioremediation.
Manuel Martinez-Garcia, David M Brazel, Brandon K Swan, Carol Arnosti, Patrick S G Chain, Krista G Reitenga, Gary Xie, Nicole J Poulton, Monica Lluesma Gomez, Dashiell E D Masland, Brian Thompson, Wendy K Bellows, Kai Ziervogel, Chien-Chi Lo, Sanaa Ahmed, Cheryl D Gleasner, Chris J Detter, Ramunas Stepanauskas   +17 more
doaj   +1 more source

Characterization of Multiple Alginate Lyases in a Highly Efficient Alginate-Degrading Vibrio Strain and Its Degradation Strategy

Applied and Environmental Microbiology, 2022
Alginate is an important carbon source in the marine environment, and vibrios are major alginate utilizers. Previous studies focused only on the characteristics of individual alginate lyases in vibrios, but few of them discussed the comprehensive ...
Xinxin He, Yunhui Zhang, Xiaolei Wang, Xiaoyu Zhu, Lei-lei Chen, Weizhi Liu, Qianqian Lyu, Lingman Ran, Haojin Cheng, Xiaohua Zhang   +9 more
semanticscholar   +1 more source

Characterization of a Novel PolyM-Preferred Alginate Lyase from Marine Vibrio splendidus OU02

Marine Drugs, 2018
Alginate lyases are enzymes that degrade alginate into oligosaccharides which possess a variety of biological activities. Discovering and characterizing novel alginate lyases has great significance for industrial and medical applications.
Jingjing Zhuang, Keke Zhang, Xiaohua Liu, Weizhi Liu, Qianqian Lyu, Aiguo Ji   +5 more
doaj   +1 more source

Abstract 2388 Examining a newly identified polysaccharide lyase family involved in glycosaminoglycans degradation [PDF]

Journal of Biological Chemistry
Mahsa Tanha, M.A. Higgins
openalex   +2 more sources

Alginate degrading enzymes: an updated comprehensive review of the structure, catalytic mechanism, modification method and applications of alginate lyases

Critical Reviews in Biotechnology, 2021
Alginate, a kind of linear acidic polysaccharide, consists of α-L-guluronate (G) and β-D-mannuronate (M). Both alginate and its degradation products (alginate oligosaccharides) possess abundant biological activities such as antioxidant activity ...
Qian Li, Ling Zheng, Zilong Guo, Tiancheng Tang, Benwei Zhu   +4 more
semanticscholar   +1 more source

Adaptations of Alteromonas sp. 76-1 to Polysaccharide Degradation: A CAZyme Plasmid for Ulvan Degradation and Two Alginolytic Systems

Frontiers in Microbiology, 2019
Studying the physiology and genomics of cultured hydrolytic bacteria is a valuable approach to decipher the biogeochemical cycling of marine polysaccharides, major nutrients derived from phytoplankton and macroalgae.
Hanna Koch, Heike M. Freese, Richard L. Hahnke, Meinhard Simon, Matthias Wietz   +4 more
doaj   +1 more source

Alginate-modifying enzymes: Biological roles and biotechnological uses

Frontiers in Microbiology, 2015
Alginate denotes a group of industrially important 1-4-linked biopolymers composed of the C-5-epimers β-D-mannuronic acid (M) and α-L-guluronic acid (G).
Helga eErtesvåg
doaj   +1 more source