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Bacterial Vaccine Antigen Discovery in the Reverse Vaccinology 2.0 Era: Progress and Challenges
The ongoing, and very serious, threat from antimicrobial resistance necessitates the development and use of preventative measures, predominantly vaccination.
Fadil A. Bidmos+3 more
doaj +1 more source
The association between life events, social support, and antibody status following thymus-dependent and thymus-independent vaccinations in healthy young adults [PDF]
This study determined whether stressful life events and social support were related to antibody status following both thymus-dependent and thymus-independent vaccinations. Life events in the previous year and customary social support were measured in 57
Burns, Victoria E.+4 more
core +1 more source
The remarkable history of pneumococcal vaccination: an ongoing challenge
Although it varies with age and geographical distribution, the global burden of infection with Streptococcus pneumoniae (pneumococcus) remains considerable.
Daniel M. Musher+2 more
doaj +1 more source
Typhoid fever is an acute infectious disease caused by Salmonella enterica subsp. enterica serovar Typhi (S. Typhi), which is still extremely common in endemic low- and middle-income countries of Asia and Africa.
M. V. Abramtseva+3 more
doaj +1 more source
Background. A 23-valent unconjugated pneumococcal polysaccharide vaccine (23vP), routinely administered at the age of 65, has limited effectiveness, and revaccination induces attenuated antibody responses.
E. Clutterbuck+10 more
semanticscholar +1 more source
Current status and challenges of meningococcal vaccines development in China
Vaccination is the most effective and economical way to prevent meningococcal meningitis. In the past few decades, with widespread use of meningococcal vaccines, the incidence of meningococcal meningitis has dropped significantly. There are some vaccines
Ying-hua XU, Ya-nan LI, Qiang YE
doaj +1 more source
Structure analysis of biologically important prokaryotic glycopolymers [PDF]
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria+1 more
core +1 more source
Protein Conjugate Polysaccharide Vaccines: Challenges in Development and Global Implementation
Pneumonia and meningitis caused by Haemophilus influenzae type b, Streptococcus pneumoniae, and Neisseria meningitidis are among the leading causes of under five mortality and morbidity.
M. Nair
semanticscholar +1 more source
Inactivated foot-and-mouth disease (FMD) vaccines generally require adjuvants to enhance the immunogenicity. To test whether the aqueous extracts of Cistanche deserticola (AECD) could be developed into a polysaccharide adjuvant for inactivated FMD ...
Ailian Zhang+6 more
doaj +1 more source
Post vaccinal temporary sensorineural hearing loss [PDF]
In our systematic research we identified four studies concerning the onset of neurological adverse events following vaccination and two excluding this association.
De Cesare, Donato Pompeo+8 more
core +1 more source