Results 71 to 80 of about 411,494 (340)

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

UDP‐glucose dehydrogenase variants cause dystroglycanopathy

Annals of Clinical and Translational Neurology, EarlyView.
Abstract UDP‐glucose dehydrogenase (UGDH) variants have been associated with hypotonia, developmental delay, and epilepsy. We report the first pathologic evidence of dystroglycanopathy in siblings with UGDH variants. Both presented around 6 months with developmental delay and elevated creatinine kinase.
Anna M. Reelfs, Carrie M. Stephan, Theresa M. Czech, Mary O. Cox, Soumya Joseph, Benjamin W. Darbro, Steven A. Moore, Kevin P. Campbell, Katherine D. Mathews   +8 more
wiley   +1 more source

Glucomannan promotes Bacteroides ovatus to improve intestinal barrier function and ameliorate insulin resistance

iMeta
Bioactive dietary fiber has been proven to confer numerous health benefits against metabolic diseases based on the modification of gut microbiota. The metabolic protective effects of glucomannan have been previously reported in animal experiments and ...
Qixing Nie, Yonggan Sun, Wenbing Hu, Chunhua Chen, Qiongni Lin, Shaoping Nie   +5 more
doaj   +1 more source

Labeling of Polysaccharides with Biotin and Fluorescent Dyes

Polysaccharides, 2023
Examples of labeling polysaccharides at hydroxyl groups are described in this paper, which are especially in demand for molecules with a blocked reducing end.
Alexander Tuzikov, Nadezhda Shilova, Tatiana Ovchinnikova, Alexey Nokel, Olga Patova, Yuriy Knirel, Tatiana Chernova, Tatiana Gorshkova, Nicolai Bovin   +8 more
doaj   +1 more source

Glucans monomer-exchange dynamics as an open chemical network [PDF]

J. Chem. Phys. 143, 244903 (2015), 2015
We describe the oligosaccharides-exchange dynamics performed by so-called D-enzymes on polysaccharides. To mimic physiological conditions, we treat this process as an open chemical network by assuming some of the polymer concentrations fixed (chemostatting).
arxiv   +1 more source

Coacervates Composed of Low‐Molecular‐Weight Compounds– Molecular Design, Stimuli Responsiveness, Confined Reaction

Advanced Biology, EarlyView.
Coacervation driven by liquid‐liquid phase separation (LLPS) of biopolymers has garnered increasing attention in biology since this leads to the formation of membraneless organelles capable of performing essential yet largely unknown functions. This review highlights recent advances in coacervates (artificial condensates) composed of low‐molecular ...
Sayuri L. Higashi, Masato Ikeda
wiley   +1 more source

Algal Polysaccharides-Based Nanomaterials: General Aspects and Potential Applications in Food and Biomedical Fields

Polysaccharides, 2023
The use of natural polymers has increased due to concern about environmental pollution caused by plastics and emerging pollutants from fossil fuels. In this context, polysaccharides from macroalgae and microalgae arise as natural and abundant resources ...
Juliana Botelho Moreira, Thaisa Duarte Santos, Camila Gonzales Cruz, Jéssica Teixeira da Silveira, Lisiane Fernandes de Carvalho, Michele Greque de Morais, Jorge Alberto Vieira Costa   +6 more
doaj   +1 more source

Cellulose-Based Light-Management Films with Improved Properties Directly Fabricated from Green Tea

Polysaccharides, 2022
Tea polyphenols are a phenolic bioactive compound extracted from tea leaves and have been widely used as additives to prepare functional materials used in packaging, adsorption and energy fields.
Jianfeng Peng, Xiaoqian Ji, Xinqun Xia, Cuiyue Li, Zhaoning Wei, Chen Chu, Zhen Xu, Jun Zhang, Guangmei Xia   +8 more
doaj   +1 more source

Design and Evaluation of 3D‐Printed Polylactic Acid Composites Reinforced with Biodegradable Bamboo Powder and Jute Powder

Advanced Engineering Materials, EarlyView.
The study investigates 3D‐printed polylactic acid (PLA) composites with biodegradable bamboo and jute powder fillers. Mechanical, thermal, structural properties, and rheological behavior are discussed to evaluate composite performance. Morphological characterization indicates uniform dispersion and adhesion of the fillers in the PLA matrix with the ...
Vimukthi Dananjaya, Yongqi Wang, Yashi Zheng, Prasad Potluri, Chamil Abeykoon   +4 more
wiley   +1 more source

Bacteroides uniformis degrades β-glucan to promote Lactobacillus johnsonii improving indole-3-lactic acid levels in alleviating colitis

Microbiome
Background Intake of dietary fiber is associated with a reduced risk of inflammatory bowel disease. β-Glucan (BG), a bioactive dietary fiber, has potential health-promoting effects on intestinal functions; however, the underlying mechanism remains ...
Shanshan Zhang, Qixing Nie, Yonggan Sun, Sheng Zuo, Chunhua Chen, Song Li, Jingrui Yang, Jielun Hu, Xingtao Zhou, Yongkang Yu, Ping Huang, Lu Lian, Mingyong Xie, Shaoping Nie   +13 more
doaj   +1 more source