Results 111 to 120 of about 257,706 (241)

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, Volume 13, Issue 26, 8 May 2026.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1179-1194, May 2026.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Water-shielding electric double layer and stable interphase engineering for durable aqueous zinc-ion batteries

Nature Communications
Aqueous zinc-ion batteries persistently encounter interface issues stemming from the water-rich electrical double layer and unstable solid-electrolyte interphase, drastically compromising reversibility and cyclability.
Zhongyou Peng, Shulong Li, Ling Tang, Jinyang Zheng, Licheng Tan, Yiwang Chen   +5 more
doaj   +1 more source

An ex vivo study of the effects of co-surfactants and conditioning additives on hair colour protection [PDF]

, 2014
This poster was exhibited as part of the Beauty and Life Science section of the Scientific ...
Daniels, Gabriela, Grant-Ross, Peter, Katakami, Kristin, Tamburic, Slobodanka   +3 more
core  

Sustainable Applications of Thymol: Advances in Formulation Technologies, Drug Delivery Systems, and Food Preservation Strategies

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Thymol is a natural monoterpene with antimicrobial, antioxidant, anti‐inflammatory, and anticancer activities relevant to food and biomedical applications. Its poor solubility and instability can be improved through nanodelivery systems. Thymol also supports sustainable food preservation and active packaging, although further clinical validation and ...
Farhang Hameed Awlqadr, Mohammed N. Saeed, Ammar B. Altemimi, Syamand Ahmed Qadir, Aryan Mahmood Faraj, Othman Abdulrahman Mohammed, Tablo H. Salih, Rawaa H. Tlay, Tarek Gamal Abedelmaksoud   +8 more
wiley   +1 more source

The Effect of Iclepertin on Hematological Parameters: An Overview of Nonclinical Studies and Clinical Trials in Healthy Volunteers and Patients with Cognitive Impairment Associated with Schizophrenia

The Journal of Clinical Pharmacology, Volume 66, Issue 5, May 2026.
Abstract There are currently no approved pharmacotherapies to treat cognitive impairment associated with schizophrenia (CIAS). Iclepertin (BI 425809) is a selective glycine transporter‐1 (GlyT1) inhibitor that was investigated for the treatment of CIAS.
Peter Nagy, Justin Corey Fowler, Holger Rosenbrock, Wenbo Tang, Eric Fu, Annie Fraser, Holly Dursema, Julia Schlichtiger, Michael Desch, Fredrik Gruenenfelder   +9 more
wiley   +1 more source

Development of an innovative method for the evaluation of fungal contamination of surfaces [PDF]

, 2008
The objective of this technical report is to compare the ability to capture fungal spores through samples performed with three different methods: Rodac contact plates, cotton pad and a pad prepared with a dusting cloth (DC pads) selected from those ...
D'ALESSANDRO, Daniela, N. Vescia, OSBORN, John Frederick, R. Grillot   +3 more
core  

Discovery of 4‐Quinazolinone‐Containing Phenylalanine Derivatives as Potent, Resistant‐Tolerant HIV Capsid Inhibitors

MedComm, Volume 7, Issue 5, May 2026.
Novel phenylalanine derivatives were identified as HIV‐1 capsid inhibitors. IC‐2i showed significant anti‐HIV‐1 activity at picomolar concentrations. ABSTRACT The HIV‐1 capsid (CA) is a validated antiviral target that plays critical roles in both the early and late stages of the viral life cycle.
Xujie Zhang, Lin Sun, Laura Walsham, Yuexi Ma, Dang Ding, Mei Wang, Fabao Zhao, Jian Zhang, Zhao Wang, Shujing Xu, Xiangyi Jiang, Yang Zhou, Erik De Clercq, Christophe Pannecouque, Chin‐Ho Chen, David C. Goldstone, Xinyong Liu, Alexej Dick, Peng Zhan   +18 more
wiley   +1 more source

Disc‐Toroid Hybrid Lipid Nanoparticles for Efficient Drug Encapsulation and Subcutaneous Delivery

Small, Volume 22, Issue 26, 8 May 2026.
This study demonstrates sub‐50 nm solid‐lipid nanoparticles with long‐term stability, high drug loading, and strong tissue compatibility. Disc‐toroid morphology is confirmed and may play a role in cellular interactions, while low cytotoxicity and minimal systemic permeation confirm depot‐like behavior. These nanoparticles represent a versatile platform
Zanelle van Niekerk, Rima Nuwayhid, Stefaniya Gaydarova, Eva Bittrich, Natalia Makarova, Susanne Boye, Christo Tzachev, Jan C. Simon, Sandra Franz, Albena Lederer   +9 more
wiley   +1 more source

Impact of Polysorbate 80 on the Antimicrobial Activity of Oregano and Thyme

Molecules
Plant-derived essential oils (EOs) possess significant antimicrobial potential against spoilage and pathogenic microorganisms. However, their efficacy can vary depending on the test method, making it difficult to standardise results.
Marta Carvalho, Joana Barbosa, Marcelo Belchior Rosendo da Silva, Helena Albano, Paula Teixeira   +4 more
doaj   +1 more source