Results 121 to 130 of about 257,706 (241)

Green Oil‐in‐Water Nanoemulsions for Delivery of Phytochemicals With Pesticidal Activity for Sustainable Food Production and Safety

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Green oil‐in‐water (O/W) nanoemulsions incorporating essential oils (EOs) and food‐derived compounds are gaining prominence as biopesticidal platforms that address the growing demand for sustainable agriculture, food safety, and reduced chemical inputs.
Anna Paula Azevedo de Carvalho   +2 more
wiley   +1 more source

Cytochrome P450 1A1 influences obesity‐induced pulmonary hypertension

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 1824-1844, May 2026.
Background and Purpose The contribution of obesity to pulmonary arterial hypertension (PAH) pathophysiology remains poorly understood. Adipose tissue synthesises estrogens via cytochrome P450 (CYP) 19A1 (aromatase), whereas circulating estrogens are metabolised in the lung by CYP1A1.
Joshua P. Dignam   +12 more
wiley   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 9, Page 2099-2122, May 2026.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata   +13 more
wiley   +1 more source

Smartphone-based pathogen diagnosis in urinary sepsis patients. [PDF]

open access: yes, 2018
BackgroundThere is an urgent need for rapid, sensitive, and affordable diagnostics for microbial infections at the point-of-care. Although a number of innovative systems have been reported that transform mobile phones into potential diagnostic tools, the
Barnes, Lucien   +10 more
core  

Delayed urticaria during treatment with anti‐CGRP monoclonal antibodies in migraine

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 5, Page 1193-1199, May 2026.
Abstract Objective To characterize clinical presentation and management of urticaria associated with calcitonin gene‐related peptide (CGRP) ‐targeting monoclonal antibodies (mAbs) for migraine prophylaxis. Background CGRP‐targeting mAbs are effective in migraine prophylaxis, but have been associated with hypersensitivity reactions, including urticaria.
Christoph T. Berger   +5 more
wiley   +1 more source

In vitro release of dibucaine hydrochloride from chitosan semisolid vehicles: emulsion and hydrophilic gels [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2017
Context: Chitosan has received attention as a functional, sustainably renewable, nontoxic and biodegradable biopolymer for pharmaceutical applications.
Nilia de la Paz   +6 more
doaj  

Enhanced brain targeting of temozolomide in polysorbate-80 coated polybutylcyanoacrylate nanoparticles

open access: yesInternational Journal of Nanomedicine, 2011
Xin-Hua Tian1, Xiao-Ning Lin1, Feng Wei1, Wei Feng1, Zhi-Chun Huang1, Peng Wang1, Lei Ren2, Yi Diao11Department of Neurosurgery, Zhongshan Hospital of Xiamen University, Xiamen, People's Republic of China; 2Research Center of Biomedical ...
Xin-Hua Tian   +3 more
doaj  

Study on preparation of VIP nanoparticles and its protection on the cell model of Parkinson’s disease [PDF]

open access: yes, 2012
帕金森病是继老年痴呆症之后世界第二大威胁人类健康的神经退行性疾病,已经严重影响1~2%老年人口的生活质量。随着生物医学技术的迅速发展,目前已经发现许多对中枢疾病(如帕金森病、老年痴呆症)具有治疗活性的多肽和蛋白类药物。但血脑屏障的存在,很大程度上限制了这些药物的临床给药和治疗作用的发挥。因此,研究多肽和蛋白类药物的新型给药系统,具有很大的研究价值和社会意义。 血管活性肠肽(Vasoactiveintestinalpolypeptide,VIP)是具有重要调节作用的神经多肽 ...
王吴芳
core  

Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments [PDF]

open access: yes, 2016
Purpose The blood brain barrier compromises glioblastoma chemotherapy. However high blood concentrations of lipophilic, alkylating drugs result in brain uptake, but cause myelosuppression.
Benattayallah, A   +12 more
core  

Strategies to deliver peptide drugs to the brain [PDF]

open access: yes, 2014
Lalatsa, Katerina   +2 more
core   +1 more source

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